Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease

MRI‐assessed locus coeruleus integrity is heritable and associated with multiple cognitive domains, mild cognitive impairment, and daytime dysfunction

(2021) Jeremy A. Elman et al.   Alzheimers & Dementia

Comorbid neuropathological diagnoses in early versus late-onset Alzheimer’s disease

(2021) Salvatore Spina et al.   BRAIN

Prospective longitudinal atrophy in Alzheimer’s disease correlates with the intensity and topography of baseline tau-PET

(2020) Renaud La Joie et al.   Science Translational Medicine

Noradrenergic Responsiveness Supports Selective Attention across the Adult Lifespan

(2020) Martin J. Dahl et al.   JOURNAL OF NEUROSCIENCE

Noradrenergic-dependent functions are associated with age-related locus coeruleus signal intensity differences

(2020) Kathy Y. Liu et al.   Nature Communications

Locus coeruleus: a new look at the blue spot

(2020) Gina R. Poe et al.   NATURE REVIEWS NEUROSCIENCE

An in vivo Probabilistic Atlas of the Human Locus Coeruleus at Ultra-high Field

(2020) Rong Ye et al.   NEUROIMAGE

A probabilistic atlas of locus coeruleus pathways to transentorhinal cortex for connectome imaging in Alzheimer's disease

(2020) Wei Sun et al.   NEUROIMAGE

Homozygosity for the A431E mutation in PSEN1 presenting with a relatively aggressive phenotype

(2019) John Parker et al.   NEUROSCIENCE LETTERS

Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases

(2019) Matthew J Betts et al.   BRAIN

An experimental model of Braak’s pretangle proposal for the origin of Alzheimer’s disease: the role of locus coeruleus in early symptom development

(2019) Abhinaba Ghosh et al.   Alzheimers Research & Therapy

Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease

(2019) Bernard J. Hanseeuw et al.   JAMA Neurology

Rostral locus coeruleus integrity is associated with better memory performance in older adults

(2019) Martin J. Dahl et al.   Nature Human Behaviour

Memory quality modulates the effect of aging on memory consolidation during sleep: Reduced maintenance but intact gain

(2019) Beate E. Muehlroth et al.   NEUROIMAGE

The developing human connectome project: A minimal processing pipeline for neonatal cortical surface reconstruction

(2018) Antonios Makropoulos et al.   NEUROIMAGE

Locus coeruleus integrity in old age is selectively related to memories linked with salient negative events

(2018) Dorothea Hämmerer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease

(2018) David Weinshenker   TRENDS IN NEUROSCIENCES

Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE)

(2018) Frank Jessen et al.   Alzheimers Research & Therapy

Imaging the evolution and pathophysiology of Alzheimer disease

(2018) William Jagust   NATURE REVIEWS NEUROSCIENCE

Novelty and Dopaminergic Modulation of Memory Persistence: A Tale of Two Systems

(2018) Adrian J. Duszkiewicz et al.   TRENDS IN NEUROSCIENCES

In vivo visualization of age-related differences in the locus coeruleus

(2018) Kathy Y. Liu et al.   NEUROBIOLOGY OF AGING

Locus coeruleus ablation exacerbates cognitive deficits, neuropathology, and lethality in P301S tau transgenic mice

(2017) Termpanit Chalermpalanupap et al.   JOURNAL OF NEUROSCIENCE

Modular organization of the brainstem noradrenaline system coordinates opposing learning states

(2017) Akira Uematsu et al.   NATURE NEUROSCIENCE

In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults

(2017) Matthew J. Betts et al.   NEUROIMAGE

Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease

(2017) A. J. Ehrenberg et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Neuropsychological Measures that Predict Progression from Mild Cognitive Impairment to Alzheimer's type dementia in Older Adults: a Systematic Review and Meta-Analysis

(2017) Sylvie Belleville et al.   NEUROPSYCHOLOGY REVIEW

Magnetic resonance imaging of the human locus coeruleus: A systematic review

(2017) Kathy Y. Liu et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Hippocampal maturity promotes memory distinctiveness in childhood and adolescence

(2017) Attila Keresztes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus

(2017) Termpanit Chalermpalanupap et al.   NEURAL PLASTICITY

Rey's Auditory Verbal Learning Test scores can be predicted from whole brain MRI in Alzheimer's disease

(2017) Elaheh Moradi et al.   NeuroImage-Clinical

Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease

(2017) Sarah C. Kelly et al.   Acta Neuropathologica Communications

Roles of tau pathology in the locus coeruleus (LC) in age-associated pathophysiology and Alzheimer’s disease pathogenesis: Potential strategies to protect the LC against aging

(2017) Akiko Satoh et al.   BRAIN RESEARCH

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

(2016) Seonjoo Lee et al.   ANNALS OF NEUROLOGY

Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database

(2016) John M. Ringman et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Locus coeruleus and dopaminergic consolidation of everyday memory

(2016) Tomonori Takeuchi et al.   NATURE

Different partial volume correction methods lead to different conclusions: An 18 F-FDG-PET study of aging

(2016) Douglas N. Greve et al.   NEUROIMAGE

The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain

(2016) Mara Mather et al.   TRENDS IN COGNITIVE SCIENCES

Potential Pathways of Abnormal Tau and α-Synuclein Dissemination in Sporadic Alzheimer's and Parkinson's Diseases

(2016) Heiko Braak et al.   Cold Spring Harbor Perspectives in Biology

Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory

(2015) Mara Mather et al.   BEHAVIORAL AND BRAIN SCIENCES

Precortical Phase of Alzheimer's Disease (AD)-Related Tau Cytoskeletal Pathology

(2015) Katharina Stratmann et al.   BRAIN PATHOLOGY

Histologic validation of locus coeruleus MRI contrast in post-mortem tissue

(2015) Noam I. Keren et al.   NEUROIMAGE

Early neurone loss in Alzheimer’s disease: cortical or subcortical?

(2015) Thomas Arendt et al.   Acta Neuropathologica Communications

Primary age-related tauopathy (PART): a common pathology associated with human aging

(2014) John F. Crary et al.   ACTA NEUROPATHOLOGICA

Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer's disease: High-resolution fast spin-echo T1-weighted imaging

(2014) Junko Takahashi et al.   Geriatrics & Gerontology International

Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis

(2014) D. C. Ryman et al.   NEUROLOGY

Evaluation of Parkinson Disease and Alzheimer Disease with the Use of Neuromelanin MR Imaging and123I-Metaiodobenzylguanidine Scintigraphy

(2013) F. Miyoshi et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Cortical surface-based analysis reduces bias and variance in kinetic modeling of brain PET data

(2013) Douglas N. Greve et al.   NEUROIMAGE

Multi-Atlas Segmentation with Joint Label Fusion

(2012) Hongzhi Wang et al.   IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

The human locus coeruleus 3-D stereotactic anatomy

(2012) P. Fernandes et al.   SURGICAL AND RADIOLOGIC ANATOMY

National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach

(2011) Thomas J. Montine et al.   ACTA NEUROPATHOLOGICA

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A Generative Model for Image Segmentation Based on Label Fusion

(2010) Mert R Sabuncu et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Partial Least Squares (PLS) methods for neuroimaging: A tutorial and review

(2010) Anjali Krishnan et al.   NEUROIMAGE

A reproducible evaluation of ANTs similarity metric performance in brain image registration

(2010) Brian B. Avants et al.   NEUROIMAGE

The Genetics of Alzheimer Disease: Back to the Future

(2010) Lars Bertram et al.   NEURON

Distinct neuroanatomical substrates and cognitive mechanisms of figure copy performance in Alzheimer's disease and behavioral variant frontotemporal dementia

(2010) Katherine L. Possin et al.   NEUROPSYCHOLOGIA

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

(2010) M. T. Heneka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comment on "Modafinil Shifts Human Locus Coeruleus to Low-Tonic, High-Phasic Activity During Functional MRI" and "Homeostatic Sleep Pressure and Responses to Sustained Attention in the Suprachiasmatic Area"

(2010) S. V. Astafiev et al.   SCIENCE

The locus coeruleus and noradrenergic modulation of cognition

(2009) Susan J. Sara   NATURE REVIEWS NEUROSCIENCE

Evaluation of 14 nonlinear deformation algorithms applied to human brain MRI registration

(2009) Arno Klein et al.   NEUROIMAGE

In vivo mapping of the human locus coeruleus

(2009) Noam I. Keren et al.   NEUROIMAGE

Staging Dementia Using Clinical Dementia Rating Scale Sum of Boxes Scores

(2008) Sid E. O’Bryant   ARCHIVES OF NEUROLOGY

The Reorienting System of the Human Brain: From Environment to Theory of Mind

(2008) Maurizio Corbetta et al.   NEURON

Visualization of Neuromelanin in the Substantia Nigra and Locus Ceruleus at 1.5T Using a 3D-gradient Echo Sequence with Magnetization Transfer Contrast

(2008) Toshiki NAKANE et al.   Magnetic Resonance in Medical Sciences