FSH blockade improves cognition in mice with Alzheimer’s disease

A novel follicle-stimulating hormone vaccine for controlling fat accumulation

(2020) Xingfa Han et al.   THERIOGENOLOGY

Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer’s disease pathologies

(2019) Jie Xiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing face validity of mouse models of Alzheimer’s disease with natural genetic variation

(2019) Kristen D. Onos et al.   PLoS Genetics

Accelerated Ovarian Failure as a Unique Model to Study Peri-Menopause Influence on Alzheimer’s Disease

(2019) Roberta Marongiu   Frontiers in Aging Neuroscience

Actions of pituitary hormones beyond traditional targets

(2018) Mone Zaidi et al.   JOURNAL OF ENDOCRINOLOGY

Sexual dimorphism in predisposition to Alzheimer's disease

(2018) Daniel W. Fisher et al.   NEUROBIOLOGY OF AGING

Epitope-specific monoclonal antibodies to FSHβ increase bone mass

(2018) Yaoting Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol

(2018) Yanjing Guo et al.   CELL RESEARCH

Delta-Secretase Phosphorylation by SRPK2 Enhances Its Enzymatic Activity, Provoking Pathogenesis in Alzheimer’s Disease

(2017) Zhi-Hao Wang et al.   MOLECULAR CELL

Blocking FSH induces thermogenic adipose tissue and reduces body fat

(2017) Peng Liu et al.   NATURE

Cellular selectivity of AAV serotypes for gene delivery in neurons and astrocytes by neonatal intracerebroventricular injection

(2017) Sean L. Hammond et al.   PLoS One

Replication Study: The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

(2017) Stephen K Horrigan et al.   eLife

Replication Study: Melanoma genome sequencing reveals frequent PREX2 mutations

(2017) Stephen K Horrigan et al.   eLife

Recombinant Human Myelin-Associated Glycoprotein Promoter Drives Selective AAV-Mediated Transgene Expression in Oligodendrocytes

(2016) Georg von Jonquieres et al.   Frontiers in Molecular Neuroscience

Policy: NIH plans to enhance reproducibility

(2014) Francis S. Collins et al.   NATURE

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease

(2014) Zhentao Zhang et al.   NATURE MEDICINE

Reproducibility

(2014) M. McNutt   SCIENCE

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Immunization with FSHβ fusion protein antigen prevents bone loss in a rat ovariectomy-induced osteoporosis model

(2013) Wenxin Geng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Postmenopausal Hormone Therapy Is Not Associated With Risk of All-Cause Dementia and Alzheimer's Disease

(2013) J. O'Brien et al.   EPIDEMIOLOGIC REVIEWS

Menopause Effects on Verbal Memory: Findings From a Longitudinal Community Cohort

(2013) C. Neill Epperson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

7,8-Dihydroxyflavone Prevents Synaptic Loss and Memory Deficits in a Mouse Model of Alzheimer’s Disease

(2013) Zhentao Zhang et al.   NEUROPSYCHOPHARMACOLOGY

Blocking antibody to the  -subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis

(2012) L.-L. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocrinology of the aging male

(2011) Andre B. Araujo et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β

(2011) Marco Straccia et al.   Journal of Neuroinflammation

Change in Follicle-Stimulating Hormone and Estradiol Across the Menopausal Transition: Effect of Age at the Final Menstrual Period

(2010) John F. Randolph et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Probing the Biology of Alzheimer's Disease in Mice

(2010) Karen H. Ashe et al.   NEURON

Amyloid  -Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

(2009) R. Minkeviciene et al.   JOURNAL OF NEUROSCIENCE

Effects of the menopause transition and hormone use on cognitive performance in midlife women

(2009) G. A. Greendale et al.   NEUROLOGY

Human chorionic gonadotropin (a luteinizing hormone homologue) decreases spatial memory and increases brain amyloid-β levels in female rats

(2008) Anne Berry et al.   HORMONES AND BEHAVIOR

Age-related decrease in stimulated glutamate release and vesicular glutamate transporters in APP/PS1 transgenic and wild-type mice

(2008) R. Minkeviciene et al.   JOURNAL OF NEUROCHEMISTRY

Episodic memory deficits are not related to altered glutamatergic synaptic transmission and plasticity in the CA1 hippocampus of the APPswe/PS1ΔE9-deleted transgenic mice model of β-amyloidosis

(2008) Arturas Volianskis et al.   NEUROBIOLOGY OF AGING