A single-cell atlas of human and mouse white adipose tissue

The Emerging Physiological Role of AGMO 10 Years after Its Gene Identification

(2021) Sabrina Sailer et al.   Life-Basel

Progenitor-like characteristics in a subgroup of UCP1+ cells within white adipose tissue

(2021) Jooman Park et al.   DEVELOPMENTAL CELL

Single-cell sequencing of human white adipose tissue identifies new cell states in health and obesity

(2021) Andrew D. Hildreth et al.   NATURE IMMUNOLOGY

Integrated analysis of multimodal single-cell data

(2021) Yuhan Hao et al.   CELL

Spatial mapping reveals human adipocyte subpopulations with distinct sensitivities to insulin

(2021) Jesper Bäckdahl et al.   Cell Metabolism

Visualization and Analysis of Whole Depot Adipose Tissue Neural Innervation

(2021) Jake W. Willows et al.   iScience

scCODA is a Bayesian model for compositional single-cell data analysis

(2021) M. Büttner et al.   Nature Communications

CellPhoneDB: inferring cell–cell communication from combined expression of multi-subunit ligand–receptor complexes

(2020) Mirjana Efremova et al.   Nature Protocols

A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

(2020) Michal Slyper et al.   NATURE MEDICINE

The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions

(2020) Thomas J. Littlejohns et al.   Nature Communications

RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro

(2020) Nellie Y. Loh et al.   Nature Communications

An atlas of cell types in the mouse epididymis and vas deferens

(2020) Vera D Rinaldi et al.   eLife

The Human and Mouse Enteric Nervous System at Single-Cell Resolution

(2020) Eugene Drokhlyansky et al.   CELL

Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity

(2020) Radiana Ferrero et al.   TRENDS IN CELL BIOLOGY

Genetic mapping of etiologic brain cell types for obesity

(2020) Pascal N Timshel et al.   eLife

Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution

(2020) Anitta Kinga Sárvári et al.   Cell Metabolism

Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling

(2020) Hyun Cheol Roh et al.   Molecular Metabolism

Bulk tissue cell type deconvolution with multi-subject single-cell expression reference

(2019) Xuran Wang et al.   Nature Communications

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Innate Immune Control of Adipose Tissue Homeostasis

(2019) Harry Kane et al.   TRENDS IN IMMUNOLOGY

Adipose Tissue Gene Expression Associations Reveal Hundreds of Candidate Genes for Cardiometabolic Traits

(2019) Chelsea K. Raulerson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

(2019) Prashant Rajbhandari et al.   eLife

Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling

(2018) Rayanne B. Burl et al.   Cell Metabolism

Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density

(2018) Jingyi Chi et al.   Cell Metabolism

Mixed-model association for biobank-scale datasets

(2018) Po-Ru Loh et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

(2018) Sara L Pulit et al.   HUMAN MOLECULAR GENETICS

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice

(2018) Chelsea Hepler et al.   eLife

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

(2018) Gleb Kichaev et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

(2018) Anubha Mahajan et al.   NATURE GENETICS

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Adapting to obesity with adipose tissue inflammation

(2017) Shannon M. Reilly et al.   Nature Reviews Endocrinology

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

What We Talk About When We Talk About Fat

(2014) Evan D. Rosen et al.   CELL

Angiogenesis and Vascular Functions in Modulation of Obesity, Adipose Metabolism, and Insulin Sensitivity

(2013) Yihai Cao   Cell Metabolism

EBF2 Determines and Maintains Brown Adipocyte Identity

(2013) Sona Rajakumari et al.   Cell Metabolism

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Different Roles of Mast Cells in Obesity and Diabetes: Lessons from Experimental Animals and Humans

(2012) Michael A. Shi et al.   Frontiers in Immunology

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci

(2011) Jonathan P. Bradfield et al.   PLoS Genetics

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

Adipose tissue macrophages: their role in adipose tissue remodeling

(2010) Takayoshi Suganami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Circulating Palmitoleate Strongly and Independently Predicts Insulin Sensitivity in Humans

(2009) N. Stefan et al.   DIABETES CARE

Human obesity as a heritable disorder of the central control of energy balance

(2009) S O'Rahilly et al.   INTERNATIONAL JOURNAL OF OBESITY