Generation of 3D lacrimal gland organoids from human pluripotent stem cells

Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs

(2021) Kimihito Nomi et al.   Cell Reports

Exploring the human lacrimal gland using organoids and single-cell sequencing

(2021) Marie Bannier-Hélaouët et al.   Cell Stem Cell

Establishment of functional epithelial organoids from human lacrimal glands

(2021) Sang Yun Jeong et al.   Stem Cell Research & Therapy

An organoid model to assay the role of CFTR in the human epididymis epithelium

(2020) Shih-Hsing Leir et al.   CELL AND TISSUE RESEARCH

Origin and Lineage Plasticity of Endogenous Lacrimal Gland Epithelial Stem/Progenitor Cells

(2020) Liana Basova et al.   iScience

Inhibition of Alk signaling promotes the induction of human salivary-gland-derived organoids

(2020) Shohei Yoshimoto et al.   Disease Models & Mechanisms

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Three Dimensional Culture of Potential Epithelial Progenitor Cells in Human Lacrimal Gland

(2019) Hui Lin et al.   Translational Vision Science & Technology

CD200 facilitates the isolation of corneal epithelial cells derived from human pluripotent stem cells

(2018) Ryuhei Hayashi et al.   Scientific Reports

Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages

(2018) Shun Shibata et al.   Cell Reports

Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells

(2017) Ryuhei Hayashi et al.   Nature Protocols

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Cytokeratin expression in mouse lacrimal gland germ epithelium

(2016) Masatoshi Hirayama et al.   EXPERIMENTAL EYE RESEARCH

Co-ordinated ocular development from human iPS cells and recovery of corneal function

(2016) Ryuhei Hayashi et al.   NATURE

Histatin-1 Expression in Human Lacrimal Epithelium

(2016) Dhara Shah et al.   PLoS One

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis

(2015) Toshiro Moroishi et al.   GENES & DEVELOPMENT

FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands

(2014) Z. Chen et al.   DEVELOPMENT

Improvement of Radiotherapy-Induced Lacrimal Gland Injury by Induced Pluripotent Stem Cell-Derived Conditioned Medium via MDK and Inhibition of the p38/JNK Pathway

(2014) Yanqing Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells

(2014) Masato Nakagawa et al.   Scientific Reports

Efficacy of Topical Mesenchymal Stem Cell Therapy in the Treatment of Experimental Dry Eye Syndrome Model

(2014) Emrullah Beyazyıldız et al.   Stem Cells International

Restoration of Human Lacrimal Function Following Platelet-Rich Plasma Injection

(2013) Marcel Y. Avila   CORNEA

Functional lacrimal gland regeneration by transplantation of a bioengineered organ germ

(2013) Masatoshi Hirayama et al.   Nature Communications

Mesenchymal Stromal Cells Treatment Attenuates Dry Eye in Patients With Chronic Graft-versus-host Disease

(2012) Jianyu Weng et al.   MOLECULAR THERAPY

Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling

(2011) C. Tsau et al.   DEVELOPMENT

Treatment of Primary Sjögren Syndrome

(2010) Manuel Ramos-Casals et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Localization of the low-affinity nerve growth factor receptor p75 in human limbal epithelial cells

(2008) Nick Di Girolamo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE