Casiopeinas of Third Generations: Synthesis, Characterization, Cytotoxic Activity and Structure–Activity Relationships of Mixed Chelate Compounds with Bioactive Secondary Ligands

DNA, a target of mixed chelate copper(II) compounds (Casiopeinas®) studied by electrophoresis, UV–vis and circular dichroism techniques.

(2022) Yeshenia Figueroa-DePaz et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Intermediate Detection in the Casiopeina–Cysteine Interaction Ending in the Disulfide Bond Formation and Copper Reduction

(2021) Lillian G. Ramírez-Palma et al.   MOLECULES

Second generation of Casiopeinas®: A joint experimental and theoretical study

(2020) Miguel Reina et al.   INORGANICA CHIMICA ACTA

Synthesis, characterization, electrochemical behavior and antioxidant activity of new copper(II) coordination compounds with curcumin derivatives

(2019) Mirela Călinescu et al.   Journal of Saudi Chemical Society

A New Family of Homoleptic Copper Complexes of Curcuminoids: Synthesis, Characterization and Biological Properties

(2019) William Meza-Morales et al.   MOLECULES

Full Structural Characterization of Homoleptic Complexes of Diacetylcurcumin with Mg, Zn, Cu, and Mn: Cisplatin-level Cytotoxicity in Vitro with Minimal Acute Toxicity in Vivo

(2019) William Meza-Morales et al.   MOLECULES

Coumarin Derivative Directly Coordinated to Lanthanides Acts as an Excellent Antenna for UV–Vis and Near-IR Emission

(2018) Óscar Guzmán-Méndez et al.   INORGANIC CHEMISTRY

Metal chelating ability and antioxidant properties of Curcumin-metal complexes – A DFT approach

(2018) C. Pitchumani Violet Mary et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

New curcumin-derived ligands and their affinity towards Ga3+, Fe3+ and Cu2+: spectroscopic studies on complex formation and stability in solution

(2018) Luca Rigamonti et al.   NEW JOURNAL OF CHEMISTRY

Synergistic effects between a copper-based metal Casiopeína III-ia and cisplatin

(2017) Silvia Graciela Davila-Manzanilla et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Essential Medicinal Chemistry of Curcumin

(2017) Kathryn M. Nelson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and biological studies of copper(II) complexes with 2-aminobenzimidazole derivatives

(2017) J. Joseph et al.   JOURNAL OF MOLECULAR STRUCTURE

Secondary Ligand Effects on the Cytotoxicity of Several Casiopeína’s Group II Compounds

(2017) María Elena Bravo-Gómez et al.   Journal of the Mexican Chemical Society

Potential roles of chemical degradation in the biological activities of curcumin

(2017) Julia Zhu et al.   Food & Function

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

(2016) Ajaikumar B Kunnumakkara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metal complexes of curcumin and curcumin derivatives for molecular imaging and anticancer therapy

(2016) Michael Pröhl et al.   COORDINATION CHEMISTRY REVIEWS

Ni(ii)/Cu(ii)/Zn(ii) 5,5-diethylbarbiturate complexes with 1,10-phenanthroline and 2,2′-dipyridylamine: synthesis, structures, DNA/BSA binding, nuclease activity, molecular docking, cellular uptake, cytotoxicity and the mode of cell death

(2016) Veysel T. Yilmaz et al.   DALTON TRANSACTIONS

Synthesis, DNA-binding, and cytotoxic studies on three copper(II) complexes of unsymmetrical synthetic analogues of curcumin

(2016) T. V. Deepthi et al.   JOURNAL OF COORDINATION CHEMISTRY

Curcumin, a Compound from Natural Sources, a True Scientific Challenge – A Review

(2016) Zorka Stanić   PLANT FOODS FOR HUMAN NUTRITION

Synthesis, DNA-binding properties and cytotoxicity evaluation of two copper(II) complexes based on curcumin

(2016) Xuan Xue et al.   TRANSITION METAL CHEMISTRY

Metal Complexes of Curcumin for Cellular Imaging, Targeting, and Photoinduced Anticancer Activity

(2015) Samya Banerjee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Metal complexes of curcumin – synthetic strategies, structures and medicinal applications

(2015) Simon Wanninger et al.   CHEMICAL SOCIETY REVIEWS

Degradation of Curcumin: From Mechanism to Biological Implications

(2015) Claus Schneider et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A curcumin-based TPA four-branched copper(II) complex probe for in vivo early tumor detection

(2015) Zongxin Pi et al.   Materials Science & Engineering C-Materials for Biological Applications

Inhibitory Effect of Curcumin-Cu(II) and Curcumin-Zn(II) Complexes on Amyloid-Beta Peptide Fibrillation

(2014) Rona Banerjee   BIOINORGANIC CHEMISTRY AND APPLICATIONS

Nano-niosomes as nanoscale drug delivery systems: An illustrated review

(2014) Saeid Moghassemi et al.   JOURNAL OF CONTROLLED RELEASE

Two copper(II) complexes of curcumin derivatives: synthesis, crystal structure and in vitro antitumor activity

(2014) Jiafeng Wang et al.   TRANSITION METAL CHEMISTRY

Drug-like chelating agents: a potential lead for Alzheimer's disease

(2014) Wenhai Huang et al.   RSC Advances

Advances in Copper Complexes as Anticancer Agents

(2013) Carlo Santini et al.   CHEMICAL REVIEWS

Delivery of Curcumin and Medicinal Effects of the Copper(II)-Curcumin Complexes

(2013) Mandy H. M. Leung et al.   CURRENT PHARMACEUTICAL DESIGN

Characteristics of curcumin using cyclic voltammetry, UV–vis, fluorescence and thermogravimetric analysis

(2013) Anna Masek et al.   ELECTROCHIMICA ACTA

Photocytotoxicity of copper(II) complexes of curcumin and N-ferrocenylmethyl-l-amino acids

(2013) Tridib K. Goswami et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Copper(II) mixed chelate compounds induce apoptosis through reactive oxygen species in neuroblastoma cell line CHP-212

(2013) Anllely Grizett Gutiérrez et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

DNA interaction studies of a novel Cu(II) complex as an intercalator containing curcumin and bathophenanthroline ligands

(2013) Nahid Shahabadi et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Synthesis and characterization of ligational behavior of curcumin drug towards some transition metal ions: Chelation effect on their thermal stability and biological activity

(2012) Moamen S. Refat   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

DNA binding and cytotoxicity of fluorescent curcumin-based Zn(ii) complexes

(2012) Daniela Pucci et al.   MedChemComm

Interaction of a Curcumin Analogue Dimethoxycurcumin with DNA

(2011) Amit Kunwar et al.   Chemical Biology & Drug Design

Metal complexes of a novel bis-β-diketone-type ligand and its copper(II) complexes of two-photon biological imaging

(2011) ShuangSheng Zhou et al.   Science China-Chemistry

Genotoxicity of the copper antineoplastic coordination complexes casiopeinas®

(2011) J. Serment-Guerrero et al.   TOXICOLOGY IN VITRO

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

(2010) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Copper Curcuminoids Containing Anthracene Groups: Fluorescent Molecules with Cytotoxic Activity

(2010) Núria Aliaga-Alcalde et al.   INORGANIC CHEMISTRY

Lanthanide(III) Complexes with 4,5-Bis(diphenylphosphinoyl)-1,2,3-triazolate and the Use of 1,10-Phenanthroline As Auxiliary Ligand

(2010) Marisol Correa-Ascencio et al.   INORGANIC CHEMISTRY

Synthesis, characterization, DNA interaction and antimicrobial screening of isatin-based polypyridyl mixed ligand Cu(II) and Zn(II) complexes

(2010) Natarajan Raman et al.   JOURNAL OF THE SERBIAN CHEMICAL SOCIETY

Evaluation ofAzadirachta indicaLeaf Fractions for in Vitro Antioxidant Potential and Protective Effects against H2O2-Induced Oxidative Damage to pBR322 DNA and Red Blood Cells

(2009) P. Manikandan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Diamagnetic Corrections and Pascal's Constants

(2009) Gordon A. Bain et al.   JOURNAL OF CHEMICAL EDUCATION

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl)benzenesulfonamide and 1,10-phenantroline. Antitumor activity in human Caco-2 cells and Jurkat T lymphocytes. Evaluation of p53 and Bcl-2 proteins in the apoptotic mechanism

(2009) José Luis García-Giménez et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Casiopeína IIgly-induced oxidative stress and mitochondrial dysfunction in human lung cancer A549 and H157 cells

(2009) Remy Kachadourian et al.   TOXICOLOGY

Antiproliferative activity and QSAR study of copper(II) mixed chelate [Cu(N–N)(acetylacetonato)]NO3 and [Cu(N–N)(glycinato)]NO3 complexes, (Casiopeínas®)

(2008) María Elena Bravo-Gómez et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Site-Specific Interactions of Cu(II) with α and β-Synuclein: Bridging the Molecular Gap between Metal Binding and Aggregation

(2008) Andrés Binolfi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY