The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The bone marrow niche regulates redox and energy balance in MLL::AF9 leukemia stem cells
Authors
Keywords
-
Journal
LEUKEMIA
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-05-26
DOI
10.1038/s41375-022-01601-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Characterization of freshly isolated mesenchymal stromal cells from healthy and multiple myeloma bone marrow: transcriptional modulation of the microenvironment.
- (2020) Daniel Alameda et al. HAEMATOLOGICA
- Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers
- (2020) Rushdia Yusuf et al. BLOOD
- Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance
- (2020) Nick van Gastel et al. Cell Metabolism
- Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells
- (2020) Zhigang Cai et al. Cell Reports
- Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
- (2020) Dorian Forte et al. Cell Metabolism
- Targeting CXCR4 in AML and ALL
- (2020) Daniel Cancilla et al. Frontiers in Oncology
- BL‐8040 CXCR4 antagonist is safe and demonstrates antileukemic activity in combination with cytarabine for the treatment of relapsed/refractory acute myelogenous leukemia: An open‐label safety and efficacy phase 2a study
- (2020) Gautam Borthakur et al. CANCER
- Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells
- (2019) Puneet Agarwal et al. Cell Stem Cell
- Antibodies targeting chemokine receptors CXCR4 and ACKR3
- (2019) Vladimir Bobkov et al. MOLECULAR PHARMACOLOGY
- Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia
- (2019) Juan Bautista Menendez-Gonzalez et al. Stem Cell Reports
- Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells
- (2019) Juan Bautista Menendez-Gonzalez et al. Scientific Reports
- Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML
- (2018) Delfim Duarte et al. Cell Stem Cell
- VDAC1 as a Player in Mitochondria-Mediated Apoptosis and Tar get for Modulating Apoptosis
- (2018) Varda Shoshan-Barmatz et al. CURRENT MEDICINAL CHEMISTRY
- Role of CXCL12 and CXCR4 in the pathogenesis of hematological malignancies
- (2018) Amnon Peled et al. CYTOKINE
- Claspin - checkpoint adaptor and DNA replication factor
- (2018) Veronique A. J. Smits et al. FEBS Journal
- VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis
- (2018) Andrea Magrì et al. Frontiers in Chemistry
- Acute myeloid leukaemia
- (2018) Nicholas J Short et al. LANCET
- Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia
- (2018) Prajwal Boddu et al. Frontiers in Oncology
- Defining the in vivo characteristics of acute myeloid leukemia cells behavior by intravital imaging
- (2018) Delfim Duarte et al. IMMUNOLOGY AND CELL BIOLOGY
- Functional genomic landscape of acute myeloid leukaemia
- (2018) Jeffrey W. Tyner et al. NATURE
- The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression
- (2017) M Abraham et al. LEUKEMIA
- Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib–dexamethasone in relapsed/refractory multiple myeloma: a Phase IIa Study
- (2017) H Ludwig et al. LEUKEMIA
- Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
- (2017) Noemí Esteras et al. Redox Biology
- Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
- (2016) Jason E. Farrar et al. CANCER RESEARCH
- Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML
- (2016) Rishi V. Puram et al. CELL
- Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia
- (2016) Noemi A. Zambetti et al. Cell Stem Cell
- Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy
- (2015) B.-S. Cho et al. BLOOD
- Knockdown of homeobox A5 by small hairpin RNA inhibits proliferation and enhances cytarabine chemosensitivity of acute myeloid leukemia cells
- (2015) NA LI et al. Molecular Medicine Reports
- Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning
- (2014) B. Saez et al. BLOOD
- Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner
- (2014) Lin Wang et al. Cell Stem Cell
- Cytokines secreted by bone marrow stromal cells protect c-KIT mutant AML cells from c-KIT inhibitor-induced apoptosis
- (2014) P M Gordon et al. LEUKEMIA
- Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
- (2014) Lorena Arranz et al. NATURE
- In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
- (2013) Peter G. Miller et al. CANCER CELL
- BCL-2 Inhibition Targets Oxidative Phosphorylation and Selectively Eradicates Quiescent Human Leukemia Stem Cells
- (2013) Eleni D. Lagadinou et al. Cell Stem Cell
- CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
- (2013) Adam Greenbaum et al. NATURE
- Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
- (2013) Lei Ding et al. NATURE
- The Prognostic Value of CXCR4 in Acute Myeloid Leukemia
- (2012) Jeong Yeal Ahn et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- The role of nuclear lamin B1 in cell proliferation and senescence
- (2011) T. Shimi et al. GENES & DEVELOPMENT
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Regulation of Cdc45 in the cell cycle and after DNA damage
- (2009) Ronan Broderick et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Kit Inhibitor APcK110 Induces Apoptosis and Inhibits Proliferation of Acute Myeloid Leukemia Cells
- (2009) S. Faderl et al. CANCER RESEARCH
- Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML
- (2008) Z. Zeng et al. BLOOD
- Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
- (2008) Gohta Goshima et al. JOURNAL OF CELL BIOLOGY
- Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest
- (2008) Wan Seok Yang et al. GENOME BIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started