Defining the in vivo characteristics of acute myeloid leukemia cells behavior by intravital imaging

The interplay of leukemia cells and the bone marrow microenvironment

(2018) Delfim Duarte et al.   BLOOD

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

(2018) Delfim Duarte et al.   Cell Stem Cell

Role of CXCL12 and CXCR4 in the pathogenesis of hematological malignancies

(2018) Amnon Peled et al.   CYTOKINE

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia

(2017) M Waibel et al.   LEUKEMIA

The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression

(2017) M Abraham et al.   LEUKEMIA

A phase 1/2 study of chemosensitization with plerixafor plus G-CSF in relapsed or refractory acute myeloid leukemia

(2017) G L Uy et al.   Blood Cancer Journal

Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside

(2017) Byung-Sik Cho et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments

(2016) Edwin D. Hawkins et al.   NATURE

Antileukemia activity of the novel peptidic CXCR4 antagonist LY2510924 as monotherapy and in combination with chemotherapy

(2015) B.-S. Cho et al.   BLOOD

CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia

(2015) Diana Passaro et al.   CANCER CELL

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance

(2015) Lauren A. Pitt et al.   CANCER CELL

Acute Myeloid Leukemia

(2015) Hartmut Döhner et al.   NEW ENGLAND JOURNAL OF MEDICINE

In vivo time-lapse imaging shows diverse niche engagement by quiescent and naturally activated hematopoietic stem cells

(2014) N. M. Rashidi et al.   BLOOD

AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model

(2013) M. Wunderlich et al.   BLOOD

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

(2012) Tajie H. Harris et al.   NATURE

The leukemic stem cell niche: current concepts and therapeutic opportunities

(2009) S. W. Lane et al.   BLOOD

A Phase II Study of Plerixafor (AMD3100) plus G-CSF for Autologous Hematopoietic Progenitor Cell Mobilization in Patients with Hodgkin Lymphoma

(2008) Amanda Cashen et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

(2008) Z. Zeng et al.   BLOOD

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100

(2008) B. Nervi et al.   BLOOD

Sampling the Cell with Anomalous Diffusion—The Discovery of Slowness

(2007) Gernot Guigas et al.   BIOPHYSICAL JOURNAL