Human Truncated Tau Induces Mature Neurofibrillary Pathology in a Mouse Model of Human Tauopathy

Immunotherapy Targeting Pathological Tau Protein in Alzheimer's Disease and Related Tauopathies

(2017) Einar M. Sigurdsson   JOURNAL OF ALZHEIMERS DISEASE

Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss

(2016) J. Di et al.   Scientific Reports

Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers

(2014) Christiane Reitz et al.   BIOCHEMICAL PHARMACOLOGY

Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer‘s disease

(2014) Ludovic Collin et al.   BRAIN

Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies

(2014) Chun-ling Dai et al.   JOURNAL OF NEURAL TRANSMISSION

Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles

(2014) D. L. Castillo-Carranza et al.   JOURNAL OF NEUROSCIENCE

p-Tau immunotherapy reduces soluble and insoluble tau in aged 3xTg-AD mice

(2014) Ken C. Walls et al.   NEUROSCIENCE LETTERS

Identification of structural determinants on tau protein essential for its pathological function: novel therapeutic target for tau immunotherapy in Alzheimer’s disease

(2014) Eva Kontsekova et al.   Alzheimers Research & Therapy

Open questions for Alzheimer’s disease immunotherapy

(2014) Todd E Golde   Alzheimers Research & Therapy

Comprehensive analysis of neurobehavior associated with histomorphological alterations in a chronic constrictive nerve injury model through use of the CatWalk XT system

(2013) Chien-Yi Chiang et al.   JOURNAL OF NEUROSURGERY

Protein Truncation as a Common Denominator of Human Neurodegenerative Foldopathies

(2013) Santosh Jadhav et al.   MOLECULAR NEUROBIOLOGY

Modeling Alzheimer’s disease in transgenic rats

(2013) Sonia Do Carmo et al.   Molecular Neurodegeneration

Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach

(2012) Nadege Zommer et al.   Current Alzheimer Research

Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models

(2011) Xiyun Chai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

First transgenic rat model developing progressive cortical neurofibrillary tangles

(2011) Peter Filipcik et al.   NEUROBIOLOGY OF AGING

P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating

(2011) Hiroki Takeuchi et al.   PLoS One

Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice

(2011) Mian Bi et al.   PLoS One

Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model

(2010) A. Boutajangout et al.   JOURNAL OF NEUROSCIENCE

Tests to assess motor phenotype in mice: a user's guide

(2009) Simon P. Brooks et al.   NATURE REVIEWS NEUROSCIENCE

Truncated tau expression levels determine life span of a rat model of tauopathy without causing neuronal loss or correlating with terminal neurofibrillary tangle load

(2008) Peter Koson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Using the CatWalk method to assess weight-bearing and pain behaviour in walking rats with ankle joint monoarthritis induced by carrageenan: Effects of morphine and rofecoxib

(2008) Kristina Ängeby Möller et al.   JOURNAL OF NEUROSCIENCE METHODS