A randomized controlled trial of 3,4-methylenedioxymethamphetamine (MDMA) and fear extinction retention in healthy adults

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

(2021) Jennifer M. Mitchell et al.   NATURE MEDICINE

Psychedelics and Psychedelic-Assisted Psychotherapy

(2020) Collin M. Reiff et al.   AMERICAN JOURNAL OF PSYCHIATRY

Long-term follow-up outcomes of MDMA-assisted psychotherapy for treatment of PTSD: a longitudinal pooled analysis of six phase 2 trials

(2020) Lisa Jerome et al.   PSYCHOPHARMACOLOGY

MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized controlled trials

(2019) Michael C. Mithoefer et al.   PSYCHOPHARMACOLOGY

Breakthrough for Trauma Treatment: Safety and Efficacy of MDMA-Assisted Psychotherapy Compared to Paroxetine and Sertraline

(2019) Allison A. Feduccia et al.   Frontiers in Psychiatry

Distinct acute effects of LSD, MDMA, and d-amphetamine in healthy subjects

(2019) Friederike Holze et al.   NEUROPSYCHOPHARMACOLOGY

Data-driven criteria to assess fear remission and phenotypic variability of extinction in rats

(2018) Jason Shumake et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

MDMA-assisted psychotherapy for PTSD: Are memory reconsolidation and fear extinction underlying mechanisms?

(2018) Allison A. Feduccia et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

3,4-methylenedioxymethamphetamine (MDMA) impairs the extinction and reconsolidation of fear memory in rats

(2018) Holly S. Hake et al.   PHYSIOLOGY & BEHAVIOR

Safety pharmacology of acute MDMA administration in healthy subjects

(2017) Patrick Vizeli et al.   JOURNAL OF PSYCHOPHARMACOLOGY

MDMA and PTSD treatment

(2017) Ben Sessa   NEUROSCIENCE LETTERS

Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3,4-methylenedioxymethamphetamine (MDMA)

(2017) Matthew B. Young et al.   PSYCHOPHARMACOLOGY

The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants?

(2016) Anya K Bershad et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The Effects of Acutely Administered 3,4-Methylenedioxymethamphetamine on Spontaneous Brain Function in Healthy Volunteers Measured with Arterial Spin Labeling and Blood Oxygen Level–Dependent Resting State Functional Connectivity

(2015) Robin L. Carhart-Harris et al.   BIOLOGICAL PSYCHIATRY

Estrogen and Extinction of Fear Memories:Implications for Posttraumatic Stress Disorder Treatment

(2015) Ebony M. Glover et al.   BIOLOGICAL PSYCHIATRY

3,4-Methylenedioxymethamphetamine facilitates fear extinction learning

(2015) M B Young et al.   Translational Psychiatry

A Randomized, Double-Blind Evaluation ofd-Cycloserine or Alprazolam Combined With Virtual Reality Exposure Therapy for Posttraumatic Stress Disorder in Iraq and Afghanistan War Veterans

(2014) Barbara Olasov Rothbaum et al.   AMERICAN JOURNAL OF PSYCHIATRY

Differential effects of MDMA and methylphenidate on social cognition

(2014) Yasmin Schmid et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Conditioned Fear Associated Phenotypes as Robust, Translational Indices of Trauma-, Stressor-, and Anxiety-Related Behaviors

(2014) Maria Anne Briscione et al.   Frontiers in Psychiatry

Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination

(2013) Cédric M. Hysek et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Human fear extinction and return of fear using reconsolidation update mechanisms: The contribution of on-line expectancy ratings

(2013) Victor Taylor Warren et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

MDMA enhances emotional empathy and prosocial behavior

(2013) Cédric M. Hysek et al.   Social Cognitive and Affective Neuroscience

A randomized, controlled pilot study of MDMA (±3,4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic Stress Disorder (PTSD)

(2012) Peter Oehen et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Impaired safety signal learning may be a biomarker of PTSD

(2011) Tanja Jovanovic et al.   NEUROPHARMACOLOGY

Neural Mechanisms of Impaired Fear Inhibition in Posttraumatic Stress Disorder

(2011) Tanja Jovanovic et al.   Frontiers in Behavioral Neuroscience

Is Ecstasy an “Empathogen”? Effects of ±3,4-Methylenedioxymethamphetamine on Prosocial Feelings and Identification of Emotional States in Others

(2010) Gillinder Bedi et al.   BIOLOGICAL PSYCHIATRY

Fear Extinction in Traumatized Civilians with Posttraumatic Stress Disorder: Relation to Symptom Severity

(2010) Seth D. Norrholm et al.   BIOLOGICAL PSYCHIATRY

Posttraumatic stress disorder may be associated with impaired fear inhibition: Relation to symptom severity

(2009) Tanja Jovanovic et al.   PSYCHIATRY RESEARCH

Timing of extinction relative to acquisition: A parametric analysis of fear extinction in humans.

(2008) Seth D. Norrholm et al.   BEHAVIORAL NEUROSCIENCE

d-Cycloserine facilitates context-specific fear extinction learning

(2008) Mark E. Bouton et al.   NEUROBIOLOGY OF LEARNING AND MEMORY