An 18-mer Peptide Derived from Prosaposin Ameliorates the Effects of Aβ1–42 Neurotoxicity on Hippocampal Neurogenesis and Memory Deficit in Mice

Altering Presenilin Gene Activity in Zebrafish Embryos Causes Changes in Expression of Genes with Potential Involvement in Alzheimer's Disease Pathogenesis

(2017) Morgan Newman et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglial dysfunction connects depression and Alzheimer’s disease

(2016) Luís Eduardo Santos et al.   BRAIN BEHAVIOR AND IMMUNITY

Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease

(2016) Mudasir Maqbool et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Influences of prenatal and postnatal stress on adult hippocampal neurogenesis: The double neurogenic niche hypothesis

(2015) Sylvia Ortega-Martínez   BEHAVIOURAL BRAIN RESEARCH

PARP-1 involvement in neurodegeneration: A focus on Alzheimer’s and Parkinson’s diseases

(2015) Sara Martire et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

A Prosaposin-Derived Peptide Alleviates Kainic Acid-Induced Brain Injury

(2015) Hiroaki Nabeka et al.   PLoS One

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

(2015) Tahir Ali et al.   Scientific Reports

Lentiviral silencing of GSK-3β in adult dentate gyrus impairs contextual fear memory and synaptic plasticity

(2015) Benjamin Chew et al.   Frontiers in Behavioral Neuroscience

Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting

(2015) Suk-yu Yau et al.   NEURAL PLASTICITY

Ser9-phosphorylated GSK3β induced by 14-3-3ζ actively antagonizes cell apoptosis in a NF-κB dependent manner

(2014) Xuejuan Gao et al.   Biochemistry and Cell Biology

The protective role of prosaposin and its receptors in the nervous system

(2014) Rebecca C. Meyer et al.   BRAIN RESEARCH

Differential expression of the alternatively spliced forms of prosaposin mRNAs in rat choroid plexus

(2014) Shouichiro Saito et al.   CELL AND TISSUE RESEARCH

How to make a hippocampal dentate gyrus granule neuron

(2014) D. X. Yu et al.   DEVELOPMENT

mTOR regulates brain morphogenesis by mediating GSK3 signaling

(2014) M. Ka et al.   DEVELOPMENT

Xanthoceraside Ameliorates Mitochondrial Dysfunction Contributing to the Improvement of Learning and Memory Impairment in Mice with Intracerebroventricular Injection of Aβ1-42

(2014) Xue-Fei Ji et al.   Evidence-based Complementary and Alternative Medicine

GSK-3 - at the crossroads of cell death and survival

(2014) U. Maurer et al.   JOURNAL OF CELL SCIENCE

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

(2014) Shichun Tu et al.   Molecular Neurodegeneration

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling

(2014) Claudia Fuchs et al.   NEUROBIOLOGY OF DISEASE

Astrogliosis

(2014) Michael V. Sofroniew   Cold Spring Harbor Perspectives in Biology

Dietary regulation of PI3K/AKT/GSK-3β pathway in Alzheimer’s disease

(2014) Yasuko Kitagishi et al.   Alzheimers Research & Therapy

Attenuation of MPTP/MPP+ toxicity in vivo and in vitro by an 18-mer peptide derived from prosaposin

(2013) H.L. Gao et al.   NEUROSCIENCE

Decrease in Prosaposin in the Dystrophic mdx Mouse Brain

(2013) Hui-ling Gao et al.   PLoS One

Autophagy and apoptosis dysfunction in neurodegenerative disorders

(2013) Saeid Ghavami et al.   PROGRESS IN NEUROBIOLOGY

β-Amyloid oligomers in aging and Alzheimer’s disease

(2013) Kathleen R. Zahs et al.   Frontiers in Aging Neuroscience

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

3,6′-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit

(2012) Isabella Russo et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer’s Disease

(2012) Barbara Biscaro et al.   Neurodegenerative Diseases

Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease

(2011) L.M. Bekris et al.   NEUROBIOLOGY OF AGING

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APP processing in Alzheimer's disease

(2011) Yun-wu Zhang et al.   Molecular Brain

Plasma biomarkers for mild cognitive impairment and Alzheimer's disease

(2009) Fei Song et al.   BRAIN RESEARCH REVIEWS

Involvement of Akt in neurite outgrowth

(2009) Danielle E. Read et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Soluble oligomeric forms of beta-amyloid (Aβ) peptide stimulate Aβ production via astrogliosis in the rat brain

(2009) J.L. Perez et al.   EXPERIMENTAL NEUROLOGY

Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Cognitive Impairment Associated With Recovery of Neurovascular Coupling

(2009) Shuko Takeda et al.   HYPERTENSION

Prosaposin in the secretome of marrow stroma-derived neural progenitor cells protects neural cells from apoptotic death

(2009) Na Li et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of PI3K-Akt Signaling Blocks Exercise-Mediated Enhancement of Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus

(2009) Elodie Bruel-Jungerman et al.   PLoS One

Tripartite synapses: astrocytes process and control synaptic information

(2009) Gertrudis Perea et al.   TRENDS IN NEUROSCIENCES

The secretion and maturation of prosaposin and procathepsin D are blocked in embryonic neural progenitor cells

(2008) Rosa Salvioli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis

(2008) Hyo-Jung Lee et al.   CANCER LETTERS