Ca 2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters

Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon

(2021) Salah A Baker et al.   eLife

Colonic Motility is Improved by the Activation of 5-HT2B Receptors on Interstitial Cells of Cajal in Diabetic Mice

(2021) Byungchang Jin et al.   GASTROENTEROLOGY

Ca2+ transients in ICC-MY define the basis for the dominance of the corpus in gastric pacemaking

(2021) Salah A. Baker et al.   CELL CALCIUM

Excitatory cholinergic responses in mouse colon intramuscular interstitial cells of Cajal are due to enhanced Ca 2+ release via M 3 receptor activation

(2020) Bernard T. Drumm et al.   FASEB JOURNAL

A novel intramuscular Interstitial Cell of Cajal is a candidate for generating pacemaker activity in the mouse internal anal sphincter

(2020) Karen I. Hannigan et al.   Scientific Reports

Ca 2+ signaling behaviours of intramuscular interstitial cells of Cajal in the murine colon

(2019) Bernard T. Drumm et al.   JOURNAL OF PHYSIOLOGY-LONDON

Endothelial TRPV4 channels modulate vascular tone by Ca 2+ ‐induced Ca 2+ release at inositol 1,4,5‐trisphosphate receptors

(2019) Helen R. Heathcote et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pacemaker function and neural responsiveness of subserosal interstitial cells of Cajal in the mouse colon

(2019) Bernard T. Drumm et al.   JOURNAL OF PHYSIOLOGY-LONDON

The effects of mitochondrial inhibitors on Ca 2+ signalling and electrical conductances required for pacemaking in interstitial cells of Cajal in the mouse small intestine

(2018) Bernard T. Drumm et al.   CELL CALCIUM

Ca2+ signalling in mouse urethral smooth muscle in situ : role of Ca2+ stores and Ca2+ influx mechanisms

(2018) Bernard T. Drumm et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mechanism-specific assay design facilitates the discovery of Nav1.7-selective inhibitors

(2018) Tania Chernov-Rogan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract

(2018) Haifeng Zheng et al.   Science Signaling

SOCE mediated by STIM and Orai is essential for pacemaker activity in the interstitial cells of Cajal in the gastrointestinal tract

(2018) Haifeng Zheng et al.   Science Signaling

Comparison of inhibitory neuromuscular transmission in the Cynomolgus monkey IAS and rectum: special emphasis on differences in purinergic transmission

(2018) CA Cobine et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy

(2018) Harry A. T. Pritchard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clustering of Ca 2+ transients in interstitial cells of Cajal defines slow wave duration

(2017) Bernard T. Drumm et al.   JOURNAL OF GENERAL PHYSIOLOGY

ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter

(2017) C. A. Cobine et al.   JOURNAL OF PHYSIOLOGY-LONDON

Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures

(2017) Moon Young Lee et al.   PLoS One

Na+-K+-Cl− cotransporter (NKCC) maintains the chloride gradient to sustain pacemaker activity in interstitial cells of Cajal

(2016) Mei Hong Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The relative contributions of store-operated and voltage-gated Ca2+ channels to the control of Ca2+ oscillations in airway smooth muscle

(2016) Sebastian Boie et al.   JOURNAL OF PHYSIOLOGY-LONDON

Store-operated calcium entry is required for sustained contraction and Ca2+ oscillations of airway smooth muscle

(2016) Jun Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Spontaneous Ca2+transients in interstitial cells of Cajal located within the deep muscular plexus of the murine small intestine

(2016) Salah A. Baker et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2

(2016) Yohan Seo et al.   PLoS One

Intracellular Ca2+ release from endoplasmic reticulum regulates slow wave currents and pacemaker activity of interstitial cells of Cajal

(2015) Mei Hong Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Principles and standards for reporting animal experiments inThe Journal of PhysiologyandExperimental Physiology

(2015) David Grundy   EXPERIMENTAL PHYSIOLOGY

Smooth Muscle Cell Genome Browser: Enabling the Identification of Novel Serum Response Factor Target Genes

(2015) Moon Young Lee et al.   PLoS One

Nitrergic neuromuscular transmission in the mouse internal anal sphincter is accomplished by multiple pathways and postjunctional effector cells

(2014) C. A. Cobine et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interactions of antagonists with subtypes of inositol 1,4,5-trisphosphate (IP3) receptor

(2014) Huma Saleem et al.   BRITISH JOURNAL OF PHARMACOLOGY

Murine genetic deficiency of neuronal nitric oxide synthase (nNOS-/-) and interstitial cells of Cajal (W/Wv): Implications for achalasia?

(2014) Michaela Müller et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Interstitial cells in the primate gastrointestinal tract

(2012) Peter J. Blair et al.   CELL AND TISSUE RESEARCH

Platelet-derived growth factor receptor α-positive cells in thetunica muscularisof human colon

(2012) Masaaki Kurahashi et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regional functional specialization and inhibitory nitrergic and nonnitrergic coneurotransmission in the human esophagus

(2011) B. Lecea et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Three independent mechanisms contribute to tetracaine inhibition of cardiac calcium release channels

(2011) Derek R. Laver et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A functional role for the ‘fibroblast-like cells’ in gastrointestinal smooth muscles

(2010) Masaaki Kurahashi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract

(2009) Pedro J. Gomez-Pinilla et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Neurotransmission in lower esophageal sphincter of W/Wv mutant mice

(2009) Y. Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The contribution of inositol 1,4,5-trisphosphate and ryanodine receptors to agonist-induced Ca2+ signaling of airway smooth muscle cells

(2009) Yan Bai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Assessment of Sarcoplasmic Reticulum Ca2+ Depletion During Spontaneous Ca2+ Waves in Isolated Permeabilized Rabbit Ventricular Cardiomyocytes

(2009) N. MacQuaide et al.   BIOPHYSICAL JOURNAL

A Model to Study the Phenotypic Changes of Interstitial Cells of Cajal in Gastrointestinal Diseases

(2009) Seungil Ro et al.   GASTROENTEROLOGY

Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass

(2009) Fredrick A. Hilliard et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

(2009) Sung Jin Hwang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Physiology of Normal Esophageal Motility

(2008) Raj K. Goyal et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter. Relevance to drug discovery for oesophageal disorders

(2007) R Farré et al.   BRITISH JOURNAL OF PHARMACOLOGY