Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation

标题
Inhibiting WEE1 Selectively Kills Histone H3K36me3-Deficient Cancers by dNTP Starvation
作者
关键词
cancer, synthetic lethality, epigenetic target, histone modification, SETD2, H3K36me3, WEE1 inhibitor, AZD1775, ATR inhibitor, CHK1 inhibitor, DNA replication, RRM2, CDK, KDM4A, H3.3K36M, iPOND, ChIP
出版物
CANCER CELL
Volume 28, Issue 5, Pages 557-568
出版商
Elsevier BV
发表日期
2015-10-25
DOI
10.1016/j.ccell.2015.09.015

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