Antitumor Activity of Rutaecarpine in Human Colorectal Cancer Cells by Suppression of Wnt/β-Catenin Signaling

Cancer statistics, 2022

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Antitumor Activity of Asperphenin B by Induction of Apoptosis and Regulation of Glyceraldehyde-3-phosphate Dehydrogenase in Human Colorectal Cancer Cells

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Natural products in drug discovery: advances and opportunities

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Synthesis and biological activity of selenopsammaplin A and its analogues as antitumor agents with DOT1L inhibitory activity

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Antitumor Activity of Pulvomycin via Targeting Activated-STAT3 Signaling in Docetaxel-Resistant Triple-Negative Breast Cancer Cells

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Cell cycle control in cancer

(2021) Helen K. Matthews et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex

(2020) Youn-Sang Jung et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Antitumor Activity of Ohmyungsamycin A through the Regulation of the Skp2-p27 Axis and MCM4 in Human Colorectal Cancer Cells

(2020) Woong Sub Byun et al.   JOURNAL OF NATURAL PRODUCTS

A novel small molecule STAT3 inhibitor SLSI-1216 suppresses proliferation and tumor growth of triple-negative breast cancer cells through apoptotic induction

(2020) Soo Kyung Park et al.   BIOCHEMICAL PHARMACOLOGY

Anti-Proliferative Activity of Nodosin, a Diterpenoid from Isodon serra, via Regulation of Wnt/β-Catenin Signaling Pathways in Human Colon Cancer Cells

(2020) Eun Seo Bae et al.   Biomolecules & Therapeutics

Antiproliferative and Antimigration Activities of Fluoro-Neplanocin A via Inhibition of Histone H3 Methylation in Triple-Negative Breast Cancer

(2020) Woong Sub Byun et al.   Biomolecules

β-catenin S45F mutation results in apoptotic resistance

(2020) Danielle Braggio et al.   ONCOGENE

Targeting the Wnt/β-catenin signaling pathway in cancer

(2020) Ya Zhang et al.   Journal of Hematology & Oncology

Cardamonin Exerts Antitumor Effect on Human Hepatocellular Carcinoma Xenografts in Athymic Nude Mice through Inhibiting NF-κβ Pathway

(2020) Nassrin Badroon et al.   Biomedicines

Inhibition of DOT1L by Half-Selenopsammaplin A Analogs Suppresses Tumor Growth and EMT-Mediated Metastasis in Triple-Negative Breast Cancer

(2020) Woong Sub Byun et al.   Pharmaceuticals

Rutaecarpine: A Promising Cardiovascular Protective Alkaloid from Evodia Rutaecarpa (Wu Zhu Yu)

(2019) Kun-ming Tian et al.   PHARMACOLOGICAL RESEARCH

Camporidines A and B: Antimetastatic and Anti-inflammatory Polyketide Alkaloids from a Gut Bacterium of Camponotus kiusiuensis

(2019) Seong-Heon Hong et al.   JOURNAL OF NATURAL PRODUCTS

Five-Year Overall Survival for Patients With Advanced Non‒Small-Cell Lung Cancer Treated With Pembrolizumab: Results From the Phase I KEYNOTE-001 Study

(2019) Edward B. Garon et al.   JOURNAL OF CLINICAL ONCOLOGY

Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A population‐based analysis

(2019) Jiwei Wang et al.   Cancer Medicine

Targeting Histone Methyltransferase DOT1L by a Novel Psammaplin A Analog Inhibits Growth and Metastasis of Triple-Negative Breast Cancer

(2019) Woong Sub Byun et al.   Molecular Therapy-Oncolytics

Esculetin suppresses tumor growth and metastasis by targeting Axin2/E-cadherin axis in colorectal cancer

(2018) Won Kyung Kim et al.   BIOCHEMICAL PHARMACOLOGY

Oxaliplatin resistance in colorectal cancer cells is mediated via activation of ABCG2 to alleviate ER stress induced apoptosis

(2018) Hsi-Hsien Hsu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Association of BRCA1/2 mutations with ovarian cancer prognosis

(2018) Yong-Wen Huang   MEDICINE

A novel selenonucleoside suppresses tumor growth by targeting Skp2 degradation in paclitaxel-resistant prostate cancer

(2018) Woong Sub Byun et al.   BIOCHEMICAL PHARMACOLOGY

Spinal bone metastases in colorectal cancer: a retrospective analysis of stability, prognostic factors and survival after palliative radiotherapy

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Causes of death among cancer patients

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Five-Year Survival in EGFR -Mutant Metastatic Lung Adenocarcinoma Treated with EGFR-TKIs

(2016) Jessica J. Lin et al.   Journal of Thoracic Oncology

Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells

(2016) Zhongyuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdk12 is essential for embryonic development and the maintenance of genomic stability

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Antitumor Activity of Phenanthroindolizidine Alkaloids Is Associated with Negative Regulation of Met Endosomal Signaling in Renal Cancer Cells

(2015) Jayoung Song et al.   CHEMISTRY & BIOLOGY

New Wnt/β-catenin target genes promote experimental metastasis and migration of colorectal cancer cells through different signals

(2015) Jingjing Qi et al.   GUT

Metastatic pattern in colorectal cancer is strongly influenced by histological subtype

(2014) N. Hugen et al.   ANNALS OF ONCOLOGY

Alkaloids as drug leads – A predictive structural and biodiversity-based analysis

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Future Directions for the Early Detection of Colorectal Cancer Recurrence

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Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis

(2013) Mijung Kwon et al.   INTERNATIONAL JOURNAL OF CANCER

6″-Debromohamacanthin A, a Bis (Indole) Alkaloid, Inhibits Angiogenesis by Targeting the VEGFR2-Mediated PI3K/AKT/mTOR Signaling Pathways

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Control of cell cycle transcription during G1 and S phases

(2013) Cosetta Bertoli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell cycle control of Wnt/β-catenin signalling by conductin/axin2 through CDC20

(2012) Michel V Hadjihannas et al.   EMBO REPORTS

Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression

(2012) Z.-Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

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Natural products in drug discovery

(2008) A HARVEY   DRUG DISCOVERY TODAY