Cerebrospinal fluid amino acids glycine, serine, and threonine in nonketotic hyperglycinemia

Genomic analyses of glycine decarboxylase neurogenic mutations yield a large-scale prediction model for prenatal disease

(2021) Joseph Farris et al.   PLoS Genetics

Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia

(2020) Kit‐Yi Leung et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Brain imaging in classic nonketotic hyperglycinemia: Quantitative analysis and relation to phenotype

(2019) Nicholas V. Stence et al.   JOURNAL OF INHERITED METABOLIC DISEASE

The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle

(2019) Samah Neame et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel SLC1A4 homozygous mutation causing congenital microcephaly, epileptic encephalopathy and spastic tetraparesis: a video-EEG and tractography – case study

(2018) Erica Pironti et al.   JOURNAL OF NEUROGENETICS

Serine Catabolism by SHMT2 Is Required for Proper Mitochondrial Translation Initiation and Maintenance of Formylmethionyl-tRNAs

(2018) Denise R. Minton et al.   MOLECULAR CELL

Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal

(2018) Haruna Tani et al.   Scientific Reports

Potential and Challenges for the Clinical Use of d-Serine As a Cognitive Enhancer

(2018) Gerson D. Guercio et al.   Frontiers in Psychiatry

Mitochondrial translation requires folate-dependent tRNA methylation

(2018) Raphael J. Morscher et al.   NATURE

ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment

(2018) Eitan Kaplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

(2018) Nora Kory et al.   SCIENCE

Computing theZScore and Centiles for Cross-sectional Analysis: A Practical Approach

(2017) Greggory R. DeVore   JOURNAL OF ULTRASOUND IN MEDICINE

Partitioning of One-Carbon Units in Folate and Methionine Metabolism Is Essential for Neural Tube Closure

(2017) Kit-Yi Leung et al.   Cell Reports

Improvement in mismatch negativity generation during d-serine treatment in schizophrenia: Correlation with symptoms

(2017) Joshua T. Kantrowitz et al.   SCHIZOPHRENIA RESEARCH

The genetic basis of classic nonketotic hyperglycinemia due to mutations in GLDC and AMT

(2016) Curtis R. Coughlin et al.   GENETICS IN MEDICINE

Characterization of Human and Yeast Mitochondrial Glycine Carriers with Implications for Heme Biosynthesis and Anemia

(2016) Paola Lunetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel European SLC1A4 variant: infantile spasms and population ancestry analysis

(2016) Judith Conroy et al.   JOURNAL OF HUMAN GENETICS

Neurodevelopmental Outcome and Treatment Efficacy of Benzoate and Dextromethorphan in Siblings with Attenuated Nonketotic Hyperglycinemia

(2016) Kendra J. Bjoraker et al.   JOURNAL OF PEDIATRICS

Serine biosynthesis and transport defects

(2016) Ayman W. El-Hattab   MOLECULAR GENETICS AND METABOLISM

Biochemical and molecular predictors for prognosis in nonketotic hyperglycinemia

(2015) Michael A. Swanson et al.   ANNALS OF NEUROLOGY

A homozygous mutation inSLC1A4in siblings with severe intellectual disability and microcephaly

(2015) M. Srour et al.   CLINICAL GENETICS

SLC1A4mutations cause a novel disorder of intellectual disability, progressive microcephaly, spasticity and thin corpus callosum

(2015) G. Heimer et al.   CLINICAL GENETICS

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

(2015) Dohoon Kim et al.   NATURE

Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

(2015) Yun Jin Pai et al.   Nature Communications

The serine shuttle between glia and neurons: implications for neurotransmission and neurodegeneration: Figure 1

(2015) Herman Wolosker et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Analysis of 953 Human Proteins from a Mitochondrial HEK293 Fraction by Complexome Profiling

(2013) Hans J. C. T. Wessels et al.   PLoS One

Serine racemase: an unconventional enzyme for an unconventional transmitter

(2012) Herman Wolosker et al.   AMINO ACIDS

Resurgence of Serine: An Often Neglected but Indispensable Amino Acid

(2012) Satish C. Kalhan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serine racemase and the serine shuttle between neurons and astrocytes

(2011) Herman Wolosker   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

d-Serine: The right or wrong isoform?

(2011) Sabine A. Fuchs et al.   BRAIN RESEARCH

Prediction of long-term outcome in glycine encephalopathy: a clinical survey

(2011) Julia B. Hennermann et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria

(2011) D. D. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalization of Mammalian Folate-Mediated One-Carbon Metabolism

(2010) Anne S. Tibbetts et al.   Annual Review of Nutrition

Multicentre age-related reference intervals for cerebrospinal fluid serine concentrations: Implications for the diagnosis and follow-up of serine biosynthesis disorders

(2010) Stuart Moat et al.   MOLECULAR GENETICS AND METABOLISM

Long-term potentiation depends on release of d-serine from astrocytes

(2010) Christian Henneberger et al.   NATURE

Two Mass-Spectrometric Techniques for Quantifying Serine Enantiomers and Glycine in Cerebrospinal Fluid: Potential Confounders and Age-Dependent Ranges

(2008) S. A. Fuchs et al.   CLINICAL CHEMISTRY

Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia

(2008) Goro KIKUCHI et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Roles of l-serine and sphingolipid synthesis in brain development and neuronal survival

(2008) Yoshio Hirabayashi et al.   PROGRESS IN LIPID RESEARCH