Safety, pharmacokinetic, and pharmacodynamic study of sibofimloc, a novel FimH blocker in patients with active Crohn's disease

The potential of FimH as a novel therapeutic target for the treatment of Crohn’s disease

(2017) Adeline Sivignon et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

(2017) Caitlin N. Spaulding et al.   NATURE

High-avidity IgA protects the intestine by enchaining growing bacteria

(2017) Kathrin Moor et al.   NATURE

Genetic Diversity and Virulence Determinants of Escherichia coli Strains Isolated from Patients with Crohn's Disease in Spain and Chile

(2017) Sandra Céspedes et al.   Frontiers in Microbiology

Macrophages Versus Escherichia coli

(2016) Anthony Buisson et al.   INFLAMMATORY BOWEL DISEASES

Molecular mechanism of bacterial type 1 and P pili assembly

(2015) A. Busch et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Cutting Edge: FimH Adhesin of Type 1 Fimbriae Is a Novel TLR4 Ligand

(2014) K. L. Mossman et al.   JOURNAL OF IMMUNOLOGY

Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

(2013) Nicolas Dreux et al.   PLoS Pathogens

Genome sequence of adherent-invasive Escherichia coli and comparative genomic analysis with other E. coli pathotypes

(2010) John HE Nash et al.   BMC GENOMICS

Biofilm formation as a novel phenotypic feature of adherent-invasive Escherichia coli (AIEC)

(2009) Margarita Martinez-Medina et al.   BMC MICROBIOLOGY

Similarity and Divergence among Adherent-Invasive Escherichia coli and Extraintestinal Pathogenic E. coli Strains

(2009) M. Martinez-Medina et al.   JOURNAL OF CLINICAL MICROBIOLOGY

FimH Adhesin of Type 1 Fimbriae Is a Potent Inducer of Innate Antimicrobial Responses Which Requires TLR4 and Type 1 Interferon Signalling

(2008) Ali A. Ashkar et al.   PLoS Pathogens

Escherichia coli isolated from a Crohn's disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells

(2007) Tonyia Eaves-Pyles et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY