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Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation

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Targeting KRAS(G12C): From Inhibitory Mechanism to Modulation of Antitumor Effects in Patients

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Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies

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Real‐World Toxicity Experience with BRAF/MEK Inhibitors in Patients with Erdheim‐Chester Disease

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Targeting Dependency on the GPX4 Lipid Peroxide Repair Pathway for Cancer Therapy

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Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion

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SHP2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple Cancer Models

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Drugging RAS: Know the enemy

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A universal fluorogenic switch for Fe(ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic tumor cells

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A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents

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A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models

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A Feasibility Study Showing [68Ga]Citrate PET Detects Prostate Cancer

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In Vitro Skin Models and Their Predictability in Defining Normal and Disease Biology, Pharmacology, and Toxicity

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Generating Primary Fibroblast Cultures from Mouse Ear and Tail Tissues

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Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells

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A Multicenter, Open-Label Phase II Clinical Trial of Combined MEK plus EGFR Inhibition for Chemotherapy-Refractory Advanced Pancreatic Adenocarcinoma

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Efficient and Stereocontrolled Synthesis of 1,2,4-Trioxolanes Useful for Ferrous Iron-Dependent Drug Delivery

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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

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Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism

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A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma

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An Iron Regulatory Gene Signature Predicts Outcome in Breast Cancer

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Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis

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Selective Role for Mek1 but not Mek2 in the Induction of Epidermal Neoplasia

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