PPP1R26 drives hepatocellular carcinoma progression by controlling glycolysis and epithelial-mesenchymal transition

Sec62 promotes stemness and chemoresistance of human colorectal cancer through activating Wnt/β-catenin pathway

(2021) Xiaofeng Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63

(2021) Yingjie Liu et al.   Nature Communications

PGC1α suppresses metastasis of HCC by inhibiting Warburg effect via PPARγ‐dependent WNT/β‐catenin/PDK1 axis

(2020) Qiaozhu Zuo et al.   HEPATOLOGY

Lowly expressed lncRNA PVT1 suppresses proliferation and advances apoptosis of glioma cells through up-regulating microRNA-128-1-5p and inhibiting PTBP1

(2020) Zheng Dahai et al.   BRAIN RESEARCH BULLETIN

The miR-30a-5p/CLCF1 axis regulates sorafenib resistance and aerobic glycolysis in hepatocellular carcinoma

(2020) Zhongqiang Zhang et al.   Cell Death & Disease

Polypyrimidine tract binding protein 1 promotes lymphatic metastasis and proliferation of bladder cancer via alternative splicing of MEIS2 and PKM

(2019) Ruihui Xie et al.   CANCER LETTERS

PKM2, function and expression and regulation

(2019) Ze Zhang et al.   Cell and Bioscience

CRAF methylation by PRMT6 regulates aerobic glycolysis driven hepatocarcinogenesis via ERK‐dependent PKM2 nuclear relocalization and activation

(2019) Tin‐Lok Wong et al.   HEPATOLOGY

A global view of hepatocellular carcinoma: trends, risk, prevention and management

(2019) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

(2019) Stefano Angiari et al.   Cell Metabolism

Circular RNA FOXP1 promotes tumor progression and Warburg effect in gallbladder cancer by regulating PKLR expression

(2019) Shouhua Wang et al.   Molecular Cancer

Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches

(2019) Karen G. de la Cruz-López et al.   Frontiers in Oncology

Proteomic investigation on bio-corona of Au, Ag and Fe nanoparticles for the discovery of triple negative breast cancer serum protein biomarkers

(2019) María del Pilar Chantada-Vázquez et al.   Journal of Proteomics

Post-Translational Modifications in Polypyrimidine Tract Binding Proteins PTBP1 and PTBP2

(2018) Jeffrey M. Pina et al.   BIOCHEMISTRY

Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16INK4a inactivation

(2018) Xiangrui Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma

(2018) Peter R. Galle et al.   JOURNAL OF HEPATOLOGY

Deacetylation of NAT10 by Sirt1 promotes the transition from rRNA biogenesis to autophagy upon energy stress

(2018) Xiaofeng Liu et al.   NUCLEIC ACIDS RESEARCH

Targeting the Ras/Raf/MEK/ERK pathway in hepatocellular carcinoma

(2017) Sufang Yang et al.   Oncology Letters

PKM1 is involved in resistance to anti-cancer drugs

(2016) Kohei Taniguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer

(2015) Weijie Guo et al.   HEPATOLOGY

Mitochondrial dysfunction induces EMT through the TGF-β/Smad/Snail signaling pathway in Hep3B hepatocellular carcinoma cells

(2015) EUI-YEUN YI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

A Novel Retinoblastoma Protein (RB) E3 Ubiquitin Ligase (NRBE3) Promotes RB Degradation and Is Transcriptionally Regulated by E2F1 Transcription Factor

(2015) Yingshuang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Epithelial to Mesenchymal Transition by E-cadherin Up-regulation via Repression of Slug Transcription and Inhibition of E-cadherin Degradation

(2014) Arghya Adhikary et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial-mesenchymal transition

(2014) A. Hamabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear PKM2 regulates the Warburg effect

(2013) Weiwei Yang et al.   CELL CYCLE

Tissue metabolomics of hepatocellular carcinoma: Tumor energy metabolism and the role of transcriptomic classification

(2013) Diren Beyoğlu et al.   HEPATOLOGY

Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells

(2012) M. Tamada et al.   CLINICAL CANCER RESEARCH

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Docking Motif-Guided Mapping of the Interactome of Protein Phosphatase-1

(2009) Annick Hendrickx et al.   CHEMISTRY & BIOLOGY

18F-FDG PET and PET/CT in the Evaluation of Cancer Treatment Response

(2009) S. Ben-Haim et al.   JOURNAL OF NUCLEAR MEDICINE

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

(2009) Charles J. David et al.   NATURE

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE