Cyclocarya paliurus triterpenoids attenuate glomerular endothelial injury in the diabetic rats via ROCK pathway

Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway

(2020) Yanyan Song et al.   Journal of Diabetes Research

Recent Advances in Drug Discovery for Diabetic Kidney Disease

(2020) Chhanda Charan Danta et al.   Expert Opinion on Drug Discovery

The Physiology, Pathology, and Therapeutic Interventions for ROCK Isoforms in Diabetic Kidney Disease

(2020) Keiichiro Matoba et al.   Frontiers in Pharmacology

Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases

(2020) Marloes Sol et al.   Frontiers in Pharmacology

Molecular Mechanisms in Early Diabetic Kidney Disease: Glomerular Endothelial Cell Dysfunction

(2020) Emelie Lassén et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulation of MAP kinase-mediated endothelial dysfunction in hyperglycemia via arginase I and eNOS dysregulation

(2019) Safoura Mazrouei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cyclocarya paliurus triterpenic acids fraction attenuates kidney injury via AMPK-mTOR-regulated autophagy pathway in diabetic rats

(2019) Xuan-Xuan Zhang et al.   PHYTOMEDICINE

Berberine ameliorates renal impairment and inhibits podocyte dysfunction by targeting the PI 3K/Akt pathway in diabetic rat

(2019) Wei‐Jian Ni et al.   Journal of Diabetes Investigation

Cyclocarya paliurus Triterpenoids Improve Diabetes-Induced Hepatic Inflammation via the Rho-Kinase-Dependent Pathway

(2019) Cuihua Jiang et al.   Frontiers in Pharmacology

Tetramethylpyrazine alleviates diabetic nephropathy through the activation of Akt signalling pathway in rats

(2019) Uddipak Rai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Triterpenic acids-enriched fraction from Cyclocarya paliurus attenuates insulin resistance and hepatic steatosis via PI3K/Akt/GSK3β pathway

(2019) Xian Zheng et al.   PHYTOMEDICINE

Update on Diabetic Nephropathy: Core Curriculum 2018

(2018) Kausik Umanath et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Loss of CLOCK under high glucose upregulates ROCK1-mediated endothelial to mesenchymal transition and aggravates plaque vulnerability

(2018) Hanfei Tang et al.   ATHEROSCLEROSIS

EndMT: A promising and controversial field

(2018) Lei Hong et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Platelet Microparticles Mediate Glomerular Endothelial Injury in Early Diabetic Nephropathy

(2018) Yang Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bamboo leaf extract ameliorates diabetic nephropathy through activating the AKT signaling pathway in rats

(2017) Changjiang Ying et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases

(2017) Evangelia Pardali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antihyperlipidaemic effect of triterpenic acid-enriched fraction from Cyclocarya paliurus leaves in hyperlipidaemic rats

(2017) Zhengfeng Wu et al.   PHARMACEUTICAL BIOLOGY

The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells

(2017) Jialing Rao et al.   Scientific Reports

Sinomenine alleviates high glucose-induced renal glomerular endothelial hyperpermeability by inhibiting the activation of RhoA/ROCK signaling pathway

(2016) Qingqiao Yin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Notoginsenoside R1 ameliorates podocyte injury in rats with diabetic nephropathy by activating the PI3K/Akt signaling pathway

(2016) Guodong Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Barrier protective effect of asiatic acid in TNF-α-induced activation of human aortic endothelial cells

(2016) Lai Yen Fong et al.   PHYTOMEDICINE

The chloroform extract of Cyclocarya paliurus attenuates high-fat diet induced non-alcoholic hepatic steatosis in Sprague Dawley rats

(2016) Zi Lin et al.   PHYTOMEDICINE

Astragaloside IV ameliorates renal injury in db/db mice

(2016) Huili Sun et al.   Scientific Reports

Antihyperlipidemic effect of Cyclocarya paliurus (Batal.) Iljinskaja extract and inhibition of apolipoprotein B48 overproduction in hyperlipidemic mice

(2015) Yonglan Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

Molecular mechanisms of diabetic kidney disease

(2014) Kimberly Reidy et al.   JOURNAL OF CLINICAL INVESTIGATION

Antihyperglycemic, antihyperlipidemic and antioxidant effects of ethanol and aqueous extracts of Cyclocarya paliurus leaves in type 2 diabetic rats

(2013) Qingqing Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

The role of the glomerular endothelium in albumin handling

(2013) Simon Satchell   Nature Reviews Nephrology

The glomerular endothelium emerges as a key player in diabetic nephropathy

(2012) Simon C. Satchell   KIDNEY INTERNATIONAL

Endothelial–Mesenchymal Transition as a Novel Mechanism for Generating Myofibroblasts during Diabetic Nephropathy

(2009) Akane Kizu et al.   AMERICAN JOURNAL OF PATHOLOGY

Endothelial-Myofibroblast Transition Contributes to the Early Development of Diabetic Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice

(2009) Jinhua Li et al.   AMERICAN JOURNAL OF PATHOLOGY