Esculetin alleviates murine lupus nephritis by inhibiting complement activation and enhancing Nrf2 signaling pathway

Coumarin glycosides from Hydrangea paniculata slow down the progression of diabetic nephropathy by targeting Nrf2 anti-oxidation and smad2/3-mediated profibrosis

(2019) Zhang Sena et al.   PHYTOMEDICINE

Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes

(2019) Yifei Zhong et al.   Nature Communications

Identification of complement inhibitory activities of two chemotherapeutic agents using a high-throughput cell imaging-based screening assay

(2018) Lingjun Zhang et al.   MOLECULAR IMMUNOLOGY

Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways

(2018) Yuhei Mizunoe et al.   Redox Biology

Nicousamide attenuates renal dysfunction and glomerular injury in remnant kidneys by inhibiting TGF-β1 internalisation and renin activity

(2018) Zhang Sen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Pharmacological Activities and Synthesis of Esculetin and Its Derivatives: A Mini-Review

(2017) Chengyuan Liang et al.   MOLECULES

Esculetin Attenuates Th2 and Th17 Responses in an Ovalbumin-Induced Asthmatic Mouse Model

(2016) Long Hongyan   INFLAMMATION

Cytoprotective effects of esculetin against oxidative stress are associated with the upregulation of Nrf2-mediated NQO1 expression via the activation of the ERK pathway

(2016) Min Ho Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

NRF2, a novel target in steroid-refractory LN?

(2016) Caroline Barranco   Nature Reviews Rheumatology

Esculetin attenuates lipopolysaccharide (LPS)-induced neuroinflammatory processes and depressive-like behavior in mice

(2016) Lingpeng Zhu et al.   PHYSIOLOGY & BEHAVIOR

Complement in Kidney Disease: Core Curriculum 2015

(2015) Joshua M. Thurman   AMERICAN JOURNAL OF KIDNEY DISEASES

You-gui Pill ameliorates renal tubulointerstitial fibrosis via inhibition of TGF-β/Smad signaling pathway

(2015) Li Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nrf2 signaling modulates cigarette smoke-induced complement activation in retinal pigmented epithelial cells

(2014) Lei Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lupus autoimmunity altered by cellular methylation metabolism

(2012) Mei-Ling Yang et al.   AUTOIMMUNITY

Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats

(2012) Sen Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Detection of glomerular complement C3 fragments by magnetic resonance imaging in murine lupus nephritis

(2011) Siranush A. Sargsyan et al.   KIDNEY INTERNATIONAL

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Glutamate Receptor Biology and its Clinical Significance in Neuropsychiatric Systemic Lupus Erythematosus

(2010) Cynthia Aranow et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Synthesis of complement protein C3 in the kidney is an important mediator of local tissue injury

(2007) Neil S. Sheerin et al.   FASEB JOURNAL