Engineered exosome as targeted lncRNA MEG3 delivery vehicles for osteosarcoma therapy

Exosomes in the tumor microenvironment as mediators of cancer therapy resistance

(2019) Irene Li et al.   Molecular Cancer

microRNA‐16‐5p‐containing exosomes derived from bone marrow‐derived mesenchymal stem cells inhibit proliferation, migration, and invasion, while promoting apoptosis of colorectal cancer cells by downregulating ITGA2

(2019) Yan Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

cRGD-decorated biodegradable polytyrosine nanoparticles for robust encapsulation and targeted delivery of doxorubicin to colorectal cancer in vivo

(2019) Xiaolei Gu et al.   JOURNAL OF CONTROLLED RELEASE

Exosomes derived from microRNA-101-3p-overexpressing human bone marrow mesenchymal stem cells suppress oral cancer cell proliferation, invasion, and migration

(2019) Chun Xie et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Bone Marrow Mesenchymal Stem Cell-Derived Exosomal MicroRNA-126-3p Inhibits Pancreatic Cancer Development by Targeting ADAM9

(2019) Dong-Mei Wu et al.   Molecular Therapy-Nucleic Acids

cRGD-functionalized nanoparticles for combination therapy of anti-endothelium dependent vessels and anti-vasculogenic mimicry to inhibit the proliferation of ovarian cancer

(2019) Yifeng Wang et al.   Acta Biomaterialia

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

(2018) Gang Jia et al.   BIOMATERIALS

Association between long non-coding RNA polymorphisms and cancer risk: a meta-analysis

(2018) Xin Huang et al.   BIOSCIENCE REPORTS

Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN

(2018) Qidi Zheng et al.   Cell Death & Disease

GSH-Activated Light-Up Near-Infrared Fluorescent Probe with High Affinity to αvβ3 Integrin for Precise Early Tumor Identification

(2018) Zhenwei Yuan et al.   ACS Applied Materials & Interfaces

Long Non-Coding RNA MEG3 Functions as a Competing Endogenous RNA to Regulate HOXA11 Expression by Sponging miR-181a in Multiple Myeloma

(2018) Xuxing Shen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Enhancing Osteosacoma Killing and CT Imaging Using Ultrahigh Drug Loading and NIR-Responsive Bismuth Sulfide@Mesoporous Silica Nanoparticles

(2018) Yao Lu et al.   Advanced Healthcare Materials

Long noncoding RNA MEG3 regulates LATS2 by promoting the ubiquitination of EZH2 and inhibits proliferation and invasion in gallbladder cancer

(2018) Longyang Jin et al.   Cell Death & Disease

Knockdown of lncRNA MEG3 inhibits viability, migration, and invasion and promotes apoptosis by sponging miR-127 in osteosarcoma cell

(2017) Yang Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A systematic review and meta-analysis of the association between long non-coding RNA polymorphisms and cancer risk

(2017) Zhi Lv et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

MSCs-Derived Exosomes: Cell-Secreted Nanovesicles with Regenerative Potential

(2016) Ana Marote et al.   Frontiers in Pharmacology

Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21

(2015) Jun Zhang et al.   CANCER BIOLOGY & THERAPY

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

(2014) Charles P. Lai et al.   ACS Nano

Potential of Cancer Cell–Derived Exosomes in Clinical Application: A Review of Recent Research Advances

(2014) Yu Sun et al.   CLINICAL THERAPEUTICS

Extracellular vesicles: emerging targets for cancer therapy

(2014) Pieter Vader et al.   TRENDS IN MOLECULAR MEDICINE

Osteosarcoma treatment – Where do we stand? A state of the art review

(2013) Anja Luetke et al.   CANCER TREATMENT REVIEWS

The roles of extracellular vesicles in cancer biology: Toward the development of novel cancer biomarkers

(2013) Takeshi Katsuda et al.   PROTEOMICS

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

The functional role of long non-coding RNA in human carcinomas

(2011) Ewan A Gibb et al.   Molecular Cancer

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Osteosarcoma incidence and survival rates from 1973 to 2004

(2009) Lisa Mirabello et al.   CANCER

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL