SifR is an Rrf2-family quinone sensor associated with catechol iron uptake in Streptococcus pneumoniae D39

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

(2022) Christopher JL Murray et al.   LANCET

Conjuring up a ghost: structural and functional characterization of FhuF, a ferric siderophore reductase from E. coli

(2021) I. B. Trindade et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

Contribution of a ZIP‐family protein to manganese uptake and infective endocarditis virulence in Streptococcus sanguinis

(2021) Tanya Puccio et al.   MOLECULAR MICROBIOLOGY

Manganese transport by Streptococcus sanguinis in acidic conditions and its impact on growth in vitro and in vivo

(2021) Tanya Puccio et al.   MOLECULAR MICROBIOLOGY

Functional asymmetry and chemical reactivity of CsoR family persulfide sensors

(2021) Joseph N Fakhoury et al.   NUCLEIC ACIDS RESEARCH

Host Stress Signals Stimulate Pneumococcal Transition from Colonization to Dissemination into the Lungs

(2021) Fayez Alghofaili et al.   mBio

Manganese Uptake, Mediated by SloABC and MntH, Is Essential for the Fitness of Streptococcus mutans

(2020) Jessica K. Kajfasz et al.   mSphere

Iron Acquisition by Bacterial Pathogens: Beyond Tris‐Catecholate Complexes

(2020) Yifan Zhang et al.   CHEMBIOCHEM

Novel Biochemical Properties and Physiological Role of the Flavin Mononucleotide Oxidoreductase YhdA from Bacillus subtilis

(2020) Luz I. Valenzuela-García et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

VuuB and IutB reduce ferric-vulnibactin in Vibrio vulnificus M2799

(2020) Naoko Okai et al.   BIOMETALS

1H, 13C, 15N backbone resonance assignments of the apo and holo forms of the ABC transporter solute binding protein PiuA from Streptococcus pneumoniae

(2020) Katherine A. Edmonds et al.   Biomolecular NMR Assignments

The Pneumococcal Iron Uptake Protein a (PiuA) Specifically Recognizes Tetradentate FeIII bis- and Mono-Catechol Complexes

(2020) Yifan Zhang et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural basis for persulfide-sensing specificity in a transcriptional regulator

(2020) Daiana A. Capdevila et al.   Nature Chemical Biology

The human innate immune protein calprotectin induces iron starvation responses in Pseudomonas aeruginosa

(2019) Emily M Zygiel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Crystal Structure of the Transcription Regulator RsrR Reveals a [2Fe-2S] Cluster Coordinated by Cys, Glu and His Residues.

(2019) Anne Volbeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Mn-sensing riboswitch activates expression of a Mn2+/Ca2+ ATPase transporter in Streptococcus

(2019) Julia E Martin et al.   NUCLEIC ACIDS RESEARCH

Staphylococcus aureus exhibits heterogeneous siderophore production within the vertebrate host

(2019) William J. Perry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial ABC transporters of iron containing compounds

(2019) Philippe Delepelaire   RESEARCH IN MICROBIOLOGY

Redox-Sensing Under Hypochlorite Stress and Infection Conditions by the Rrf2-Family Repressor HypR in Staphylococcus aureus

(2018) Vu Van Loi et al.   ANTIOXIDANTS & REDOX SIGNALING

Toward a mechanistic understanding of Feo-mediated ferrous iron uptake

(2018) Alexandrea E. Sestok et al.   Metallomics

Streptococcus pneumoniae: transmission, colonization and invasion

(2018) Jeffrey N. Weiser et al.   NATURE REVIEWS MICROBIOLOGY

RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization

(2018) David G. Glanville et al.   PLoS Pathogens

‘Democratized’ genomic enzymology web tools for functional assignment

(2018) Rémi Zallot et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Manganese acquisition is essential for virulence of Enterococcus faecalis

(2018) Cristina Colomer-Winter et al.   PLoS Pathogens

Dirhodium (II) complex interferes with iron-transport system to exert antibacterial action against Streptococcus pneumoniae

(2018) Xiao-Yan Yang et al.   Journal of Proteomics

Genome-Wide Characterization of the Fur Regulatory Network Reveals a Link between Catechol Degradation and Bacillibactin Metabolism in Bacillus subtilis

(2018) Hualiang Pi et al.   mBio

Vibrio cholerae VciB Mediates Iron Reduction

(2017) Eric D. Peng et al.   JOURNAL OF BACTERIOLOGY

Perturbation of manganese metabolism disrupts cell division inStreptococcus pneumoniae

(2017) Julia E. Martin et al.   MOLECULAR MICROBIOLOGY

Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding

(2017) Anne Volbeda et al.   Nature Communications

Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in Streptococcus pneumoniae D39

(2017) John P. Lisher et al.   mSphere

ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules

(2016) Haim Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Bacteria in an intense competition for iron: Key component of theCampylobacter jejuniiron uptake system scavenges enterobactin hydrolysis product

(2016) Daniel J. Raines et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Two distinct mechanisms of transcriptional regulation by the redox sensor YodB

(2016) Sang Jae Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated Translatomics with Proteomics to Identify Novel Iron–Transporting Proteins in Streptococcus pneumoniae

(2016) Xiao-Yan Yang et al.   Frontiers in Microbiology

Characterization of a putative NsrR homologue in Streptomyces venezuelae reveals a new member of the Rrf2 superfamily

(2016) John T. Munnoch et al.   Scientific Reports

Thiol-based redox switches in prokaryotes

(2015) Melanie Hillion et al.   BIOLOGICAL CHEMISTRY

Host stress hormone norepinephrine stimulates pneumococcal growth, biofilm formation and virulence gene expression

(2014) Sara Sandrini et al.   BMC MICROBIOLOGY

spxA2, encoding a regulator of stress resistance inBacillus anthracis, is controlled by SaiR, a new member of the Rrf2 protein family

(2014) Michiko M. Nakano et al.   MOLECULAR MICROBIOLOGY

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport

(2014) Ines A Ehrnstorfer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Structural and Functional Basis of Catalysis Mediated by NAD(P)H:acceptor Oxidoreductase (FerB) of Paracoccus denitrificans

(2014) Vojtěch Sedláček et al.   PLoS One

Interactions of a Periplasmic Binding Protein with a Tetradentate Siderophore Mimic

(2013) Daniel J. Raines et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Physical Characterization of the Manganese-Sensing Pneumococcal Surface Antigen Repressor from Streptococcus pneumoniae

(2013) John P. Lisher et al.   BIOCHEMISTRY

Catecholamine norepinephrine diminishes lung epithelial cell adhesion of Streptococcus pneumoniae by binding iron

(2013) X. F. Gonzales et al.   MICROBIOLOGY-SGM

Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity

(2013) Senapathy Rajagopalan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Manganese acquisition and homeostasis at the host-pathogen interface

(2013) John P. Lisher et al.   Frontiers in Cellular and Infection Microbiology

Characterization of the [2Fe-2S] Cluster of Escherichia coli Transcription Factor IscR

(2012) Angela S. Fleischhacker et al.   BIOCHEMISTRY

Siderocalins: Siderophore binding proteins evolved for primary pathogen host defense

(2012) Allyson K Sia et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A fine scale phenotype-genotype virulence map of a bacterial pathogen

(2012) T. van Opijnen et al.   GENOME RESEARCH

Interplay between Manganese and Iron in Pneumococcal Pathogenesis: Role of the Orphan Response Regulator RitR

(2012) Cheryl-Lynn Y. Ong et al.   INFECTION AND IMMUNITY

Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR inEscherichia coli

(2012) Jennifer L. Giel et al.   MOLECULAR MICROBIOLOGY

The Siderophore-Interacting Protein YqjH Acts as a Ferric Reductase in Different Iron Assimilation Pathways ofEscherichia coli

(2011) Marcus Miethke et al.   BIOCHEMISTRY

Insights into the Rrf2 repressor family - the structure of CymR, the global cysteine regulator of Bacillus subtilis

(2011) William Shepard et al.   FEBS Journal

Staphylococcus aureus Transporters Hts, Sir, and Sst Capture Iron Liberated from Human Transferrin by Staphyloferrin A, Staphyloferrin B, and Catecholamine Stress Hormones, Respectively, and Contribute to Virulence

(2011) Federico C. Beasley et al.   INFECTION AND IMMUNITY

The Bradyrhizobium japonicum frcB Gene Encodes a Diheme Ferric Reductase

(2011) S. K. Small et al.   JOURNAL OF BACTERIOLOGY

Fur and the Novel Regulator YqjI Control Transcription of the Ferric Reductase Gene yqjH in Escherichia coli

(2010) S. Wang et al.   JOURNAL OF BACTERIOLOGY

Instability of ackA (Acetate Kinase) Mutations and Their Effects on Acetyl Phosphate and ATP Amounts in Streptococcus pneumoniae D39

(2010) S. Ramos-Montanez et al.   JOURNAL OF BACTERIOLOGY

Nutritional immunity beyond iron: a role for manganese and zinc

(2009) Thomas E Kehl-Fie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A single intersubunit salt bridge affects oligomerization and catalytic activity in a bacterial quinone reductase

(2009) Alexandra Binter et al.   FEBS Journal

CymR, the master regulator of cysteine metabolism inStaphylococcus aureus, controls host sulphur source utilization and plays a role in biofilm formation

(2009) Olga Soutourina et al.   MOLECULAR MICROBIOLOGY

Biochemical characterization of l-DOPA 2,3-dioxygenase, a single-domain type I extradiol dioxygenase from lincomycin biosynthesis

(2008) Keri L. Colabroy et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The CymR Regulator in Complex with the Enzyme CysK Controls Cysteine Metabolism inBacillus subtilis

(2008) Catherine Tanous et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of the RitR DNA-binding domain by a Ser-Thr phosphokinase: implications for global gene regulation in the streptococci

(2008) Andrew T. Ulijasz et al.   MOLECULAR MICROBIOLOGY

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY