Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer’s disease of 3×Tg mice

The clinical promise of biomarkers of synapse damage or loss in Alzheimer’s disease

(2020) Martí Colom-Cadena et al.   Alzheimers Research & Therapy

Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances

(2020) Wenzhang Wang et al.   Molecular Neurodegeneration

Cognitive improvements and reduction in amyloid plaque deposition by saikosaponin D treatment in a murine model of Alzheimer's disease

(2020) Li Zhou et al.   Experimental and Therapeutic Medicine

Swimming exercise improves cognitive and behavioral disorders in male NMRI mice with sporadic Alzheimer-like disease

(2020) Hamideh Bashiri et al.   PHYSIOLOGY & BEHAVIOR

Beyond the neuron–cellular interactions early in Alzheimer disease pathogenesis

(2019) Christopher M. Henstridge et al.   NATURE REVIEWS NEUROSCIENCE

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

Multi-sensory Gamma Stimulation Ameliorates Alzheimer’s-Associated Pathology and Improves Cognition

(2019) Anthony J. Martorell et al.   CELL

Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients

(2019) Matthew K. Tobin et al.   Cell Stem Cell

Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection

(2019) Chinnakkaruppan Adaikkan et al.   NEURON

Leaving the Lights on Using Gamma Entrainment to Protect against Neurodegeneration

(2019) Ana Catarina Ferreira et al.   NEURON

Protective effect of exercise training against the progression of Alzheimer’s disease in 3xTg-AD mice

(2019) Donghyun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

Physical exercise ameliorates psychiatric disorders and cognitive dysfunctions by hippocampal mitochondrial function and neuroplasticity in post-traumatic stress disorder

(2019) Jin-Hee Seo et al.   EXPERIMENTAL NEUROLOGY

The effects of exercise on hypothalamic neurodegeneration of Alzheimer’s disease mouse model

(2018) Khoa Do et al.   PLoS One

Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model

(2018) Alfonso Grimaldi et al.   Cell Death & Disease

Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice

(2018) Yoelvis García-Mesa et al.   JOURNAL OF ALZHEIMERS DISEASE

Enhanced Expression of the Voltage-Dependent Anion Channel 1 (VDAC1) in Alzheimer's Disease Transgenic Mice: An Insight into the Pathogenic Effects of Amyloid-β

(2018) Mar Cuadrado-Tejedor et al.   JOURNAL OF ALZHEIMERS DISEASE

Microglia in neurodegeneration

(2018) Suzanne Hickman et al.   NATURE NEUROSCIENCE

Noninvasive 40-Hz light flicker to recruit microglia and reduce amyloid beta load

(2018) Annabelle C. Singer et al.   Nature Protocols

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Exercise Plays a Preventive Role Against Alzheimer's Disease

(2017) Zsolt Radak et al.   JOURNAL OF ALZHEIMERS DISEASE

Meta-analysis of synaptic pathology in Alzheimer's disease reveals selective molecular vesicular machinery vulnerability

(2016) Martijn C. de Wilde et al.   Alzheimers & Dementia

Mitochondrial DNA mutations increase in early stage Alzheimer disease and are inconsistent with oxidative damage

(2016) Jake G. Hoekstra et al.   ANNALS OF NEUROLOGY

Human tau increases amyloid β plaque size but not amyloid β-mediated synapse loss in a novel mouse model of Alzheimer's disease

(2016) Rosemary J. Jackson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The amyloid cascade hypothesis: are we poised for success or failure?

(2016) Eric Karran et al.   JOURNAL OF NEUROCHEMISTRY

Decreased peripheral brain-derived neurotrophic factor levels in Alzheimer’s disease: a meta-analysis study (N=7277)

(2016) X-Y Qin et al.   MOLECULAR PSYCHIATRY

Gamma frequency entrainment attenuates amyloid load and modifies microglia

(2016) Hannah F. Iaccarino et al.   NATURE

Apolipoprotein E4 Causes Age-Dependent Disruption of Slow Gamma Oscillations during Hippocampal Sharp-Wave Ripples

(2016) Anna K. Gillespie et al.   NEURON

Astrocytes in physiological aging and Alzheimer’s disease

(2016) J.J. Rodríguez-Arellano et al.   NEUROSCIENCE

Long-term exposure to ELF-MF ameliorates cognitive deficits and attenuates tau hyperphosphorylation in 3xTg AD mice

(2016) Yu Hu et al.   NEUROTOXICOLOGY

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Early detection of cognitive deficits in the 3xTg-AD mouse model of Alzheimer's disease

(2015) Kurt R. Stover et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Treadmill Running Reverses Cognitive Declines due to Alzheimer Disease

(2015) JINKYUNG CHO et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Standardized Herbal Formula PM012 Decreases Cognitive Impairment and Promotes Neurogenesis in the 3xTg AD Mouse Model of Alzheimer’s Disease

(2015) Minsook Ye et al.   MOLECULAR NEUROBIOLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers

(2015) I. Marques-Aleixo et al.   NEUROSCIENCE

Identification of neurotoxic cytokines by profiling Alzheimer’s disease tissues and neuron culture viability screening

(2015) Levi B. Wood et al.   Scientific Reports

Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease

(2014) Adi Shruster et al.   BEHAVIOURAL BRAIN RESEARCH

Microglial dysfunction in brain aging and Alzheimer's disease

(2014) Kira Irving Mosher et al.   BIOCHEMICAL PHARMACOLOGY

Amyloid- -Induced Action Potential Desynchronization and Degradation of Hippocampal Gamma Oscillations Is Prevented by Interference with Peptide Conformation Change and Aggregation

(2014) F. R. Kurudenkandy et al.   JOURNAL OF NEUROSCIENCE

Physical exercise improves synaptic dysfunction and recovers the loss of survival factors in 3xTg-AD mouse brain

(2014) Susana Revilla et al.   NEUROPHARMACOLOGY

Alterations in hippocampal network oscillations and theta-gamma coupling arise before Aβ overproduction in a mouse model of Alzheimer's disease

(2013) Romain Goutagny et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Amyloid beta deregulates astroglial mGluR5-mediated calcium signaling via calcineurin and Nf-kB

(2013) Dmitry Lim et al.   GLIA

Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice

(2013) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Role of Nuclear Receptor on Regulation of BDNF and Neuroinflammation in Hippocampus of β-Amyloid Animal Model of Alzheimer’s Disease

(2013) Atish Prakash et al.   NEUROTOXICITY RESEARCH

Motile Axonal Mitochondria Contribute to the Variability of Presynaptic Strength

(2013) Tao Sun et al.   Cell Reports

Apolipoprotein E4 effects in Alzheimer’s disease are mediated by synaptotoxic oligomeric amyloid-β

(2012) Robert M. Koffie et al.   BRAIN

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

(2012) B M Brown et al.   MOLECULAR PSYCHIATRY

Chronic exercise ameliorates the neuroinflammation in mice carrying NSE/htau23

(2011) Yea-Hyun Leem et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Impaired mitochondrial function abolishes gamma oscillations in the hippocampus through an effect on fast-spiking interneurons

(2011) R. G. Whittaker et al.   BRAIN

The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis

(2011) Jie Zhao et al.   Journal of Neuroinflammation

Physical Exercise, Aging, and Mild Cognitive Impairment

(2010) Yonas E. Geda et al.   ARCHIVES OF NEUROLOGY

Neuroinflammatory processes in Alzheimer’s disease

(2010) Michael T. Heneka et al.   JOURNAL OF NEURAL TRANSMISSION

Effect of Huprine X on β-Amyloid, Synaptophysin and α7 Neuronal Nicotinic Acetylcholine Receptors in the Brain of 3xTg-AD and APPswe Transgenic Mice

(2010) Monika M. Hedberg et al.   Neurodegenerative Diseases

Probing the Biology of Alzheimer's Disease in Mice

(2010) Karen H. Ashe et al.   NEURON

Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease

(2010) Hyun-Sub Um et al.   NEUROSCIENCE RESEARCH

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial permeability transition pore in Alzheimer's disease: Cyclophilin D and amyloid beta

(2009) Heng Du et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

(2009) P. Hemachandra Reddy   EXPERIMENTAL NEUROLOGY

The Alzheimer's disease mitochondrial cascade hypothesis: An update

(2009) Russell H. Swerdlow et al.   EXPERIMENTAL NEUROLOGY

Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease

(2009) Gjumrakch Aliev et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

Co-occurrence of Alzheimer's disease β-amyloid and tau pathologies at synapses

(2008) Reisuke H. Takahashi et al.   NEUROBIOLOGY OF AGING