KIFC1 is a novel potential therapeutic target for breast cancer

Discovery and Mechanistic Study of a Small Molecule Inhibitor for Motor Protein KIFC1

(2013) Jiaquan Wu et al.   ACS Chemical Biology

Design, Synthesis, and Biological Evaluation of an Allosteric Inhibitor of HSET that Targets Cancer Cells with Supernumerary Centrosomes

(2013) Ciorsdaidh A. Watts et al.   CHEMISTRY & BIOLOGY

Identification of Pim Kinases as Novel Targets for PJ34 with Confounding Effects in PARP Biology

(2012) Albert A. Antolín et al.   ACS Chemical Biology

Centrosome amplification in tumorigenesis

(2012) Simon J. Anderhub et al.   CANCER LETTERS

Let's huddle to prevent a muddle: centrosome declustering as an attractive anticancer strategy

(2012) A Ogden et al.   CELL DEATH AND DIFFERENTIATION

Role of PARP Inhibitors in Cancer Biology and Therapy

(2012) D. Davar et al.   CURRENT MEDICINAL CHEMISTRY

Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET

(2012) Julia Kleylein-Sohn et al.   JOURNAL OF CELL SCIENCE

A phenanthrene derived PARP inhibitor is an extra-centrosomes de-clustering agent exclusively eradicating human cancer cells

(2011) Asher Castiel et al.   BMC CANCER

The PARP inhibitor PJ34 causes a PARP1-independent, p21 dependent mitotic arrest

(2011) Dana L. Madison et al.   DNA REPAIR

Inhibition of ADP Ribosylation Prevents and Cures Helicobacter-Induced Gastric Preneoplasia

(2010) I. M. Toller et al.   CANCER RESEARCH

Overexpression of Kinesins Mediates Docetaxel Resistance in Breast Cancer Cells

(2009) S. De et al.   CANCER RESEARCH

The Expression of Three Genes in Primary Non-Small Cell Lung Cancer Is Associated with Metastatic Spread to the Brain

(2009) H. Grinberg-Rashi et al.   CLINICAL CANCER RESEARCH

Centrosome function in cancer: guilty or innocent?

(2009) Deborah Zyss et al.   TRENDS IN CELL BIOLOGY

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

(2008) M. Kwon et al.   GENES & DEVELOPMENT