Urolithin A Inactivation of TLR3/TRIF Signaling to Block the NF-κB/STAT1 Axis Reduces Inflammation and Enhances Antioxidant Defense in Poly(I:C)-Induced RAW264.7 Cells

Immunomodulatory Role of Urolithin A on Metabolic Diseases

(2021) Ashley Mulcahy Toney et al.   Biomedicines

Diospyrin Modulates Inflammation in Poly I:C-Induced Macrophages via ER Stress-Induced Calcium-CHOP Pathway

(2020) Hyun-Ju Kim et al.   Processes

Extracellular RNAs-TLR3 signaling contributes to cognitive decline in a mouse model of postoperative cognitive dysfunction

(2019) Chan Chen et al.   BRAIN BEHAVIOR AND IMMUNITY

SARI attenuates colon inflammation by promoting STAT1 degradation in intestinal epithelial cells

(2019) Lei Dai et al.   Mucosal Immunology

Composition and Potential Health Benefits of Pomegranate: A Review

(2019) Vesna Vučić et al.   CURRENT PHARMACEUTICAL DESIGN

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways

(2018) Maciej Czerkies et al.   Nature Communications

Crosstalk of toll-like receptors signaling and Nrf2 pathway for regulation of inflammation

(2018) Shikha Mohan et al.   BIOMEDICINE & PHARMACOTHERAPY

NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches

(2018) Farzane Sivandzade et al.   Redox Biology

Poly (I:C) impairs NO donor-induced relaxation by overexposure to NO via the NF-kappa B/iNOS pathway in rat superior mesenteric arteries

(2017) Makoto Ando et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs

(2017) Nizar M. Yousif et al.   GLIA

TLR-7 agonist attenuates airway reactivity and inflammation through Nrf2-mediated antioxidant protection in a murine model of allergic asthma

(2016) Ahmed Nadeem et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Poly(I:C) increases the expression of mPGES-1 and COX-2 in rat primary microglia

(2016) Antonio Carlos Pinheiro de Oliveira et al.   Journal of Neuroinflammation

Toll-Like Receptor Signaling Induces Nrf2 Pathway Activation through p62-Triggered Keap1 Degradation

(2015) Shasha Yin et al.   MOLECULAR AND CELLULAR BIOLOGY

Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation

(2015) Wei Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transfection of poly(I:C) can induce reactive oxygen species-triggered apoptosis and interferon-β-mediated growth arrest in human renal cell carcinoma cells via innate adjuvant receptors and the 2-5A system

(2014) Nanae Harashima et al.   Molecular Cancer

Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

(2014) Naoki Takemura et al.   Nature Communications

IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C

(2013) Tyler C. Moore et al.   FEBS LETTERS

The high Nrf2 expression in human acute myeloid leukemia is driven by NF- B and underlies its chemo-resistance

(2012) S. A. Rushworth et al.   BLOOD

Cooperative Activation of CCL5 Expression by TLR3 and Tumor Necrosis Factor-α or Interferon-γ through Nuclear Factor-ĸB or STAT-1 in Airway Epithelial Cells

(2010) Tetsuya Homma et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

The TAK1-JNK cascade is required for IRF3 function in the innate immune response

(2009) Bianhong Zhang et al.   CELL RESEARCH

NADPH Oxidase 2 Interaction with TLR2 Is Required for Efficient Innate Immune Responses to Mycobacteria via Cathelicidin Expression

(2009) C.-S. Yang et al.   JOURNAL OF IMMUNOLOGY

Adenovirus Induction of IRF3 Occurs through a Binary Trigger Targeting Jun N-Terminal Kinase and TBK1 Kinase Cascades and Type I Interferon Autocrine Signaling

(2009) M. Nociari et al.   JOURNAL OF VIROLOGY

TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

(2008) M MATSUMOTO et al.   ADVANCED DRUG DELIVERY REVIEWS