Activity of the novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 against osteosarcoma

Review of the Molecular Pathogenesis of Osteosarcoma

(2014) Jin-Peng He et al.   Asian Pacific Journal of Cancer Prevention

Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation

(2014) Yun-Rong Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New molecular insights into osteosarcoma targeted therapy

(2013) Jilong Yang et al.   CURRENT OPINION IN ONCOLOGY

Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing’s sarcoma

(2013) Xing Dai et al.   MEDICAL SCIENCE MONITOR

Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations

(2013) X Chen et al.   ONCOGENE

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Activation of AMP-Activated Protein Kinase Contributes to Doxorubicin-Induced Cell Death and Apoptosis in Cultured Myocardial H9c2 Cells

(2011) Min-Bin Chen et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Chemotherapeutic adjuvant treatment for osteosarcoma: Where do we stand?

(2011) Jakob K. Anninga et al.   EUROPEAN JOURNAL OF CANCER

Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors

(2011) E. Vilar et al.   MOLECULAR CANCER THERAPEUTICS

Network systems biology for targeted cancer therapies

(2011) Ting-Ting Zhou   Chinese Journal of Cancer

Allosteric and ATP-competitive kinase inhibitors of mTOR for cancer treatment

(2010) Carlos García-Echeverría   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Zoledronic Acid Potentiates mTOR Inhibition and Abolishes the Resistance of Osteosarcoma Cells to RAD001 (Everolimus): Pivotal Role of the Prenylation Process

(2010) G. Moriceau et al.   CANCER RESEARCH

The Efficacy of the Novel Dual PI3-Kinase/mTOR Inhibitor NVP-BEZ235 Compared with Rapamycin in Renal Cell Carcinoma

(2010) D. C. Cho et al.   CLINICAL CANCER RESEARCH

Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell

(2010) Min-Bin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia

(2009) A. M. Roccaro et al.   BLOOD

The Applicability of mTOR Inhibition in Solid Tumors

(2009) I.R. Konings et al.   CURRENT CANCER DRUG TARGETS

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway

(2008) Frédéric Stauffer et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

(2008) S.-M. Maira et al.   MOLECULAR CANCER THERAPEUTICS