IL‐1 receptor antagonist plus pentoxifylline and zinc for severe alcohol‐associated hepatitis

Design and rationale of a multicenter defeat alcoholic steatohepatitis trial: (DASH) randomized clinical trial to treat alcohol-associated hepatitis

(2020) Srinivasan Dasarathy et al.   Contemporary Clinical Trials

Endpoints and patient stratification in clinical trials for alcoholic hepatitis

(2019) Philippe Mathurin et al.   JOURNAL OF HEPATOLOGY

Inflammatory pathways in alcoholic steatohepatitis

(2019) Bin Gao et al.   JOURNAL OF HEPATOLOGY

Microbiome as a therapeutic target in alcohol-related liver disease

(2019) Shiv K. Sarin et al.   JOURNAL OF HEPATOLOGY

Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

(2019) Yi Duan et al.   NATURE

Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual Data

(2018) Alexandre Louvet et al.   GASTROENTEROLOGY

Application of prognostic scores in the STOPAH trial: Discriminant function is no longer the optimal scoring system in alcoholic hepatitis

(2018) Ewan H. Forrest et al.   JOURNAL OF HEPATOLOGY

In Patients With Severe Alcoholic Hepatitis, Prednisolone Increases Susceptibility to Infection and Infection-Related Mortality, and Is Associated With High Circulating Levels of Bacterial DNA

(2017) Nikhil Vergis et al.   GASTROENTEROLOGY

Main drivers of outcome differ between short term and long term in severe alcoholic hepatitis: A prospective study

(2017) Alexandre Louvet et al.   HEPATOLOGY

Intestinal fungi contribute to development of alcoholic liver disease

(2017) An-Ming Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-1 inhibition facilitates recovery from liver injury and promotes regeneration of hepatocytes in alcoholic hepatitis in mice

(2017) Arvin Iracheta-Vellve et al.   LIVER INTERNATIONAL

Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia

(2016) David W. Crabb et al.   GASTROENTEROLOGY

Combining Data From Liver Disease Scoring Systems Better Predicts Outcomes of Patients With Alcoholic Hepatitis

(2015) Alexandre Louvet et al.   GASTROENTEROLOGY

Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis

(2015) Siddharth Singh et al.   GASTROENTEROLOGY

Systemic inflammatory response and serum lipopolysaccharide levels predict multiple organ failure and death in alcoholic hepatitis

(2015) Javier Michelena et al.   HEPATOLOGY

Corticosteroids and occurrence of and mortality from infections in severe alcoholic hepatitis: a meta-analysis of randomized trials

(2015) Bashar S. Hmoud et al.   LIVER INTERNATIONAL

Prednisolone or Pentoxifylline for Alcoholic Hepatitis

(2015) Mark R. Thursz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Granulocyte Colony-Stimulating Factor in Severe Alcoholic Hepatitis: A Randomized Pilot Study

(2014) Virendra Singh et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Host-Microbiome Interactions in Alcoholic Liver Disease

(2014) Peng Chen et al.   Gut and Liver

Trends in Alcoholic Hepatitis-related Hospitalizations, Financial Burden, and Mortality in the United States

(2014) Raxitkumar Jinjuvadia et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Prednisolone With vs Without Pentoxifylline and Survival of Patients With Severe Alcoholic Hepatitis

(2013) Philippe Mathurin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Invasive aspergillosis in patients with severe alcoholic hepatitis

(2013) Thierry Gustot et al.   JOURNAL OF HEPATOLOGY

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice

(2012) Jan Petrasek et al.   JOURNAL OF CLINICAL INVESTIGATION

Prevention of hepatorenal syndrome in patients with cirrhosis and ascites

(2011) Pankaj Tyagi et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

The role of zinc deficiency in alcohol-induced intestinal barrier dysfunction

(2010) Wei Zhong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Clinical Characteristics and Mortality of Hospitalized Alcoholic Hepatitis Patients in the United States

(2010) Suthat Liangpunsakul   JOURNAL OF CLINICAL GASTROENTEROLOGY

Alcoholic liver disease and the gut-liver axis

(2010) Gyongyi Szabo   WORLD JOURNAL OF GASTROENTEROLOGY

Endotoxemia and gut barrier dysfunction in alcoholic liver disease

(2009) Radhakrishna Rao   HEPATOLOGY

Pentoxifylline versus prednisolone for severe alcoholic hepatitis: A randomized controlled trial

(2009) Binay Krishna De et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support

(2008) Paul A. Harris et al.   JOURNAL OF BIOMEDICAL INFORMATICS