NFkB ‐signaling promotes glial reactivity and suppresses Müller glia‐mediated neuron regeneration in the mammalian retina

The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar

(2021) Federica Maria Conedera et al.   Molecular Neurodegeneration

HMGA Proteins in Stemness and Differentiation of Embryonic and Adult Stem Cells

(2020) Silvia Parisi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina

(2020) Nikolas L. Jorstad et al.   Cell Reports

Diverse Signaling by TGFβ Isoforms in Response to Focal Injury is Associated with Either Retinal Regeneration or Reactive Gliosis

(2020) Federica Maria Conedera et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina

(2020) Isabella Palazzo et al.   DEVELOPMENT

SingleCellSignalR: inference of intercellular networks from single-cell transcriptomics

(2020) Simon Cabello-Aguilar et al.   NUCLEIC ACIDS RESEARCH

Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration

(2020) Mi-Sun Lee et al.   eLife

Reprogramming Müller Glia to Regenerate Retinal Neurons

(2020) Manuela Lahne et al.   Annual Review of Vision Science

Microglia versus Monocytes: Distinct Roles in Degenerative Diseases of the Retina

(2020) Chen Yu et al.   TRENDS IN NEUROSCIENCES

Transgenic inhibition of astroglial NF-κB restrains the neuroinflammatory and neurodegenerative outcomes of experimental mouse glaucoma

(2020) Xiangjun Yang et al.   Journal of Neuroinflammation

Gene regulatory networks controlling vertebrate retinal regeneration

(2020) Thanh Hoang et al.   SCIENCE

Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout

(2020) Lei Xu et al.   Redox Biology

Microglia Suppress Ascl1-Induced Retinal Regeneration in Mice

(2020) Levi Todd et al.   Cell Reports

Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction

(2019) Federica Maria Conedera et al.   GLIA

Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification

(2019) Brian S. Clark et al.   NEURON

Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina

(2019) Levi Todd et al.   Journal of Neuroinflammation

Cellular Specificity of NF-κB Function in the Nervous System

(2019) Erica C. Dresselhaus et al.   Frontiers in Immunology

A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization

(2019) Paulina M. Wojnarowicz et al.   Cell Reports

Dynamic changes in microglial and macrophage characteristics during degeneration and regeneration of the zebrafish retina

(2018) Diana M. Mitchell et al.   Journal of Neuroinflammation

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Monocyte infiltration rather than microglia proliferation dominates the early immune response to rapid photoreceptor degeneration

(2018) Sarah J. Karlen et al.   Journal of Neuroinflammation

Inflammation-induced Id2 promotes plasticity in regulatory T cells

(2018) Sung-Min Hwang et al.   Nature Communications

BMP- and TGFβ-signaling regulate the formation of Müller glia-derived progenitor cells in the avian retina

(2017) Levi Todd et al.   GLIA

Microglia activation is essential for BMP7-mediated retinal reactive gliosis

(2017) Subramanian Dharmarajan et al.   Journal of Neuroinflammation

Activation inhibitors of nuclear factor kappa B protect neurons against the NMDA-induced damage in the rat retina

(2017) Kenji Sakamoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Stimulation of functional neuronal regeneration from Müller glia in adult mice

(2017) Nikolas L. Jorstad et al.   NATURE

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina

(2017) David T. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development

(2016) T.F. Sumter et al.   CURRENT MOLECULAR MEDICINE

Reactive gliosis in the adult zebrafish retina

(2016) Jennifer L. Thomas et al.   EXPERIMENTAL EYE RESEARCH

Lhx2 Is an Essential Factor for Retinal Gliogenesis and Notch Signaling

(2016) Jimmy de Melo et al.   JOURNAL OF NEUROSCIENCE

Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging

(2016) Scott J. Robbie et al.   NEUROBIOLOGY OF AGING

Inhibition of the TGFβ Pathway Enhances Retinal Regeneration in Adult Zebrafish

(2016) Christoph Tappeiner et al.   PLoS One

Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina

(2016) E. G. O’Koren et al.   Scientific Reports

Heparin-binding EGF-like growth factor (HB-EGF) stimulates the proliferation of Müller glia-derived progenitor cells in avian and murine retinas

(2015) Levi Todd et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Transgenic expression of the proneural transcription factor Ascl1 in Müller glia stimulates retinal regeneration in young mice

(2015) Yumi Ueki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive microglia and macrophage facilitate the formation of Müller glia-derived retinal progenitors

(2014) Andy J. Fischer et al.   GLIA

Müller glial cell reprogramming and retina regeneration

(2014) Daniel Goldman   NATURE REVIEWS NEUROSCIENCE

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

Chemokine Mediated Monocyte Trafficking into the Retina: Role of Inflammation in Alteration of the Blood-Retinal Barrier in Diabetic Retinopathy

(2014) Sampathkumar Rangasamy et al.   PLoS One

Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish

(2014) Jenny R. Lenkowski et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Regulation of NF-κB by TNF family cytokines

(2014) Matthew S. Hayden et al.   SEMINARS IN IMMUNOLOGY

A comparative analysis of Müller glia-mediated regeneration in the vertebrate retina

(2013) Donika Gallina et al.   EXPERIMENTAL EYE RESEARCH

Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling

(2013) Jenny R. Lenkowski et al.   GLIA

New functions of Müller cells

(2013) Andreas Reichenbach et al.   GLIA

Microglia: Scapegoat, Saboteur, or Something Else?

(2013) A. Aguzzi et al.   SCIENCE

TGF-β-Id1 Signaling Opposes Twist1 and Promotes Metastatic Colonization via a Mesenchymal-to-Epithelial Transition

(2013) Marko Stankic et al.   Cell Reports

Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis

(2012) Roberta Brambilla et al.   Journal of Neuroinflammation

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

(2012) Sandeep N. Shah et al.   PLoS One

Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina

(2011) Minhua Wang et al.   Journal of Neuroinflammation

The stem cell potential of glia: lessons from reactive gliosis

(2011) Stefanie Robel et al.   NATURE REVIEWS NEUROSCIENCE

Colony-Stimulating Factor-1 Receptor Inhibitors for the Treatment of Cancer and Inflammatory Disease

(2009) Sharmila Patel et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Mitogen-activated protein kinase-signaling regulates the ability of Müller glia to proliferate and protect retinal neurons against excitotoxicity

(2009) Andy J. Fischer et al.   GLIA

Serotonin released from amacrine neurons is scavenged and degraded in bipolar neurons in the retina

(2009) Kanika Ghai et al.   JOURNAL OF NEUROCHEMISTRY

Excitotoxic Death of Retinal Neurons In Vivo Occurs via a Non-Cell-Autonomous Mechanism

(2009) F. Lebrun-Julien et al.   JOURNAL OF NEUROSCIENCE

Cellular signaling and factors involved in Müller cell gliosis: Neuroprotective and detrimental effects

(2009) Andreas Bringmann et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration

(2008) Ryan Thummel et al.   EXPERIMENTAL EYE RESEARCH

The Proneural Basic Helix-Loop-Helix Gene Ascl1a Is Required for Retina Regeneration

(2008) B. V. Fausett et al.   JOURNAL OF NEUROSCIENCE