EZH2 expression is a prognostic factor in childhood intracranial ependymoma: A Canadian Pediatric Brain Tumor Consortium study

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

(2014) S. C. Mack et al.   NATURE

A phase I trial of MK-2206 in children with refractory malignancies: A Children's Oncology Group study

(2014) Maryam Fouladi et al.   PEDIATRIC BLOOD & CANCER

Efficacy of the dual PI3K and mTOR inhibitor NVP-BEZ235 in combination with nilotinib against BCR-ABL-positive leukemia cells involves the ABL kinase domain mutation

(2013) Seiichi Okabe et al.   CANCER BIOLOGY & THERAPY

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

(2013) Eunhee Kim et al.   CANCER CELL

Chromatin Regulator PRC2 Is a Key Regulator of Epigenetic Plasticity in Glioblastoma

(2013) A. Natsume et al.   CANCER RESEARCH

EZH2 and ALDH1 expression in ductal carcinoma in situ: Complex association with recurrence and progression to invasive breast cancer

(2013) Erik S. Knudsen et al.   CELL CYCLE

CDKN2A deletion in pediatric versus adult glioblastomas and predictive value of p16 immunohistochemistry

(2013) Suvendu Purkait et al.   NEUROPATHOLOGY

Differential Effects of Selective Inhibitors Targeting the PI3K/AKT/mTOR Pathway in Acute Lymphoblastic Leukemia

(2013) Susanne Badura et al.   PLoS One

A prognostic gene expression signature in infratentorial ependymoma

(2012) Khalida Wani et al.   ACTA NEUROPATHOLOGICA

Distinct disease-risk groups in pediatric supratentorial and posterior fossa ependymomas

(2012) Catherine Godfraind et al.   ACTA NEUROPATHOLOGICA

Polycomb Protein EZH2 Regulates Tumor Invasion via the Transcriptional Repression of the Metastasis Suppressor RKIP in Breast and Prostate Cancer

(2012) G. Ren et al.   CANCER RESEARCH

Correlation of p53 and KI-67 expression with grade and subtype of ependymoma

(2012) C Sundaram et al.   Indian Journal of Pathology and Microbiology

Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells

(2012) Junko Kikuchi et al.   LUNG CANCER

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysis

(2012) Piergiorgio Modena et al.   NEURO-ONCOLOGY

Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells

(2012) Irina Alimova et al.   NEURO-ONCOLOGY

Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy

(2011) Min-Yu Chen et al.   CANCER

Delineation of Two Clinically and Molecularly Distinct Subgroups of Posterior Fossa Ependymoma

(2011) Hendrik Witt et al.   CANCER CELL

Pediatric infratentorial ependymoma: prognostic significance of anaplastic histology

(2011) Ji Hoon Phi et al.   JOURNAL OF NEURO-ONCOLOGY

Dual Inhibition of PI3K and mTORC1/2 Signaling by NVP-BEZ235 as a New Therapeutic Strategy for Acute Myeloid Leukemia

(2010) N. Chapuis et al.   CLINICAL CANCER RESEARCH

Molecular Staging of Intracranial Ependymoma in Children and Adults

(2010) Andrey Korshunov et al.   JOURNAL OF CLINICAL ONCOLOGY

Cross-species genomics matches driver mutations and cell compartments to model ependymoma

(2010) Robert A. Johnson et al.   NATURE

Adult ependymal tumors: prognosis and the M. D. Anderson Cancer Center experience

(2010) T. S. Armstrong et al.   NEURO-ONCOLOGY

EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

(2009) M.-L. Suva et al.   CANCER RESEARCH

The genetic and epigenetic basis of ependymoma

(2009) Stephen C. Mack et al.   CHILDS NERVOUS SYSTEM

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

(2009) T. B. Miranda et al.   MOLECULAR CANCER THERAPEUTICS

Ki67 index in intracranial ependymoma: a promising histopathological candidate biomarker

(2008) M Preusser et al.   HISTOPATHOLOGY

Predictive Value of Tumor Ki-67 Expression in Two Randomized Trials of Adjuvant Chemoendocrine Therapy for Node-Negative Breast Cancer

(2008) Giuseppe Viale et al.   JNCI-Journal of the National Cancer Institute

Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

(2008) Yutaka Kondo et al.   NATURE GENETICS

Differentiation of Neural Stem Cells into Oligodendrocytes: Involvement of the Polycomb Group Protein Ezh2

(2008) Falak Sher et al.   STEM CELLS