In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease
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Title
In silico evaluation of particle transport and deposition in the airways of individual patients with chronic obstructive pulmonary disease
Authors
Keywords
Chronic obstructive pulmonary disease, Computational fluid dynamics, Computed tomography, Lagrangian multiphase model, Dry powder inhaler
Journal
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
Volume 174, Issue -, Pages 10-19
Publisher
Elsevier BV
Online
2022-03-27
DOI
10.1016/j.ejpb.2022.03.010
References
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Note: Only part of the references are listed.- Computational fluid dynamics of the airways after left‐upper pulmonary lobectomy: a case study
- (2021) Marta Tullio et al. International Journal for Numerical Methods in Biomedical Engineering
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- (2021) Kaveh Ahookhosh et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2020) Claudio Sorino et al. European Journal of Internal Medicine
- Development of human respiratory airway models: A review
- (2020) Kaveh Ahookhosh et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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- (2020) Mohammad S. Islam et al. International Journal of Environmental Research and Public Health
- Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract
- (2020) Fen Huang et al. ADVANCED DRUG DELIVERY REVIEWS
- Dry powder inhaler aerosol deposition in a model of tracheobronchial airways: Validating CFD predictions with in vitro data
- (2020) Kaveh Ahookhosh et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Airway Deposition of Extrafine Inhaled Triple Therapy in Patients with COPD: A Model Approach Based on Functional Respiratory Imaging Computer Simulations
- (2020) Omar S Usmani et al. International Journal of Chronic Obstructive Pulmonary Disease
- In silico optimization of targeted aerosol delivery in upper airways via Inhaled Volume Tracking
- (2020) Metar Heller-Algazi et al. CLINICAL BIOMECHANICS
- The effect of airway motion and breathing phase during imaging on CFD simulations of respiratory airflow
- (2020) Chamindu C. Gunatilaka et al. COMPUTERS IN BIOLOGY AND MEDICINE
- Estimating inter-patient variability of dispersion in dry powder inhalers using CFD-DEM simulations
- (2020) Benedict Benque et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Computational modeling of lung deposition of inhaled particles in chronic obstructive pulmonary disease (COPD) patients: identification of gaps in knowledge and data
- (2019) Koustav Ganguly et al. CRITICAL REVIEWS IN TOXICOLOGY
- Understanding Dry Powder Inhalers: Key Technical and Patient Preference Attributes
- (2019) Mark L. Levy et al. ADVANCES IN THERAPY
- CFD modelling of air and particle flows in different airway models
- (2019) Y.H. Kim et al. JOURNAL OF AEROSOL SCIENCE
- A particle technology approach toward designing dry-powder inhaler formulations for personalized medicine in respiratory diseases
- (2019) Kazunori Kadota et al. ADVANCED POWDER TECHNOLOGY
- Challenges and strategies in drug delivery systems for treatment of pulmonary infections
- (2019) Duy-Khiet Ho et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Numerical simulations of particle behaviour in a realistic human airway model with varying inhalation patterns
- (2019) Kazunori Kadota et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Regional flow and deposition variability in adult female lungs: A numerical simulation pilot study
- (2018) Kamran Poorbahrami et al. CLINICAL BIOMECHANICS
- In Vitro Evaluation of Optimal Inhalation Flow Patterns for Commercial Dry Powder Inhalers and Pressurized Metered Dose Inhalers With Human Inhalation Flow Pattern Simulator
- (2018) Daiki Hira et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Aerosol Delivery Devices for Obstructive Lung Diseases
- (2018) Roy A Pleasants et al. Respiratory Care
- Large eddy simulation of the flow pattern in an idealized mouth-throat under unsteady inspiration flow conditions
- (2018) Xinguang Cui et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Numerical investigation of deposition mechanism in three mouth–throat models
- (2018) F. Huang et al. POWDER TECHNOLOGY
- Evaluation of highly branched cyclic dextrin in inhalable particles of combined antibiotics for the pulmonary delivery of anti-tuberculosis drugs
- (2017) Kazunori Kadota et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Three-dimensional unsteady large eddy simulation of the vortex structures and the mono-disperse particle dispersion in the idealized human upper respiratory system
- (2017) Xinguang Cui et al. JOURNAL OF AEROSOL SCIENCE
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- (2017) Kazunori Kadota et al. Journal of the Taiwan Institute of Chemical Engineers
- Assistance for Predicting Deposition of Tranilast Dry Powder in Pulmonary Airways by Computational Fluid Dynamics
- (2017) Kazunori Kadota et al. Journal of Pharmaceutical Innovation
- Dry powder inhalable formulations for anti-tubercular therapy
- (2016) Thaigarajan Parumasivam et al. ADVANCED DRUG DELIVERY REVIEWS
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- (2016) P. Worth Longest et al. Journal of Aerosol Medicine and Pulmonary Drug Delivery
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- A new methodology for targeting drug-aerosols in the human respiratory system
- (2008) Clement Kleinstreuer et al. INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
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