Systematic comparison of activity and mechanism of antimicrobial peptides against nosocomial pathogens

An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P. aeruginosa and negligible toxicity in vitro and in vivo

(2021) Jingjing Zhou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antibiofilm activity of host defence peptides: complexity provides opportunities

(2021) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

Cationic Antimicrobial Peptides Are Leading the Way to Combat Oropathogenic Infections

(2021) Bruce Lin et al.   ACS Infectious Diseases

The Microbiologist’s Guide to Membrane Potential Dynamics

(2020) Jonatan M. Benarroch et al.   TRENDS IN MICROBIOLOGY

The value of antimicrobial peptides in the age of resistance

(2020) Maria Magana et al.   LANCET INFECTIOUS DISEASES

Antimicrobial Peptides: Classification, Design, Application and Research Progress in Multiple Fields

(2020) Yuchen Huan et al.   Frontiers in Microbiology

Design of N-Terminal Derivatives from a Novel Dermaseptin Exhibiting Broad-Spectrum Antimicrobial Activity against Isolates from Cystic Fibrosis Patients

(2019) Yuan Ying et al.   Biomolecules

Tuneable poration: host defense peptides as sequence probes for antimicrobial mechanisms

(2018) Marc-Philipp Pfeil et al.   Scientific Reports

A novel cecropin B-derived peptide with antibacterial and potential anti-inflammatory properties

(2018) Jiarong Wang et al.   PeerJ

Insight into the interactions, residue snorkeling, and membrane disordering potency of a single antimicrobial peptide into different lipid bilayers

(2017) Majid Jafari et al.   PLoS One

Membrane interactions of proline-rich antimicrobial peptide, Chex1-Arg20, multimers

(2016) Wenyi Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

C-Terminal Modification and Multimerization Increase the Efficacy of a Proline-Rich Antimicrobial Peptide

(2016) Wenyi Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Systematic Analysis of Intracellular-targeting Antimicrobial Peptides, Bactenecin 7, Hybrid of Pleurocidin and Dermaseptin, Proline–Arginine-rich Peptide, and Lactoferricin B, by UsingEscherichia coliProteome Microarrays

(2016) Yu-Hsuan Ho et al.   MOLECULAR & CELLULAR PROTEOMICS

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

PEP-FOLD3: fasterde novostructure prediction for linear peptides in solution and in complex

(2016) Alexis Lamiable et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of Antimicrobial Resistance in ESKAPE Pathogens

(2016) Sirijan Santajit et al.   Biomed Research International

Antimicrobial Peptides: An Emerging Category of Therapeutic Agents

(2016) Margit Mahlapuu et al.   Frontiers in Cellular and Infection Microbiology

C-Terminal Modifications Broaden Activity of the Proline-Rich Antimicrobial Peptide, Chex1-Arg20

(2015) Wenyi Li et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Multimerization of a Proline-Rich Antimicrobial Peptide, Chex-Arg20, Alters Its Mechanism of Interaction with the Escherichia coli Membrane

(2015) Wenyi Li et al.   CHEMISTRY & BIOLOGY

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

(2015) Jumin Lee et al.   Journal of Chemical Theory and Computation

A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells

(2015) Claudia Monteiro et al.   MOLECULAR PHARMACEUTICS

Proline-rich antimicrobial peptides: potential therapeutics against antibiotic-resistant bacteria

(2014) Wenyi Li et al.   AMINO ACIDS

Finding alternatives to antibiotics

(2014) Heather K. Allen et al.   Annals of the New York Academy of Sciences

Dye-release assay for investigation of antimicrobial peptide activity in a competitive lipid environment

(2014) Marc-Antoine Sani et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Improved PEP-FOLD Approach for Peptide and Miniprotein Structure Prediction

(2014) Yimin Shen et al.   Journal of Chemical Theory and Computation

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

PEP-FOLD: an updated de novo structure prediction server for both linear and disulfide bonded cyclic peptides

(2012) P. Thevenet et al.   NUCLEIC ACIDS RESEARCH

OPM database and PPM web server: resources for positioning of proteins in membranes

(2011) Mikhail A. Lomize et al.   NUCLEIC ACIDS RESEARCH

Broad-Spectrum Antimicrobial Peptides by Rational Combinatorial Design and High-Throughput Screening: The Importance of Interfacial Activity

(2009) Ramesh Rathinakumar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY