Article
Green & Sustainable Science & Technology
Sulaman Muhammad, Yanchun Pan, Cosimo Magazzino, Yusen Luo, Muhammad Waqas
Summary: This paper analyzes the impact of the fintech industry on environmental efficiency in selected EU countries and finds that fintech industry and e-commerce have a positive effect on environmental efficiency, while high-tech industry reduces it. The results also show that economic growth and green finance investment promote environmental efficiency, while industrialization and R&D deteriorate it.
JOURNAL OF CLEANER PRODUCTION
(2022)
Article
Business
Chenguang Wang, Cuixia Qiao, Rahil Irfan Ahmed, Dervis Kirikkaleli
Summary: This study examines the impact of bank finance and institutional quality on technological innovation in BRICS countries, finding a positive correlation with high technology exports and GDP. The study suggests that easing finance access and strengthening institutions are important for promoting innovation.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Article
Business
Jianqiang Gu, Kostas Gouliamos, Oana-Ramona Lobont, Moldovan Nicoleta-Claudia
Summary: This study examines the impact of technological innovation and natural resources on financial development, finding that human capital strengthens the relationship between technological innovation-led financial development. Human capital, technological innovation, and continuous investment in R&D can shift natural resources into other productive sectors of the economy, turning the curse into a blessing.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Article
Business
Zhilun Jiao, Muhammad Shehryar Shahid, Nawazish Mirza, Zhixiong Tan
Summary: This study evaluates the success of fintech in different countries and cities, suggesting that countries should concentrate their efforts on developing a fintech ecosystem in fewer cities to improve their Global Fintech Scores and specialize in specific core areas. By focusing resources in specific cities, countries can accelerate the wave of the fourth industrial revolution.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Article
Business
Ravi S. Achrol, Philip Kotler
Summary: Interfirm networks are crucial for market organization, but the exponential growth in knowledge and technologies is leading to disruptive changes in the business environment and increasing uncertainty. This paper argues that networks are likely to reorganize around four strategic foci including distributed micro manufacturing, AI mediated consumption, distributed innovation, and distributed marketing. The analysis suggests that distributed networks will employ more polyarchic market mechanisms and marketing will develop a horizontal strategic posture, integrating production within a distributed micro-manufacturing framework.
JOURNAL OF BUSINESS RESEARCH
(2022)
Article
Green & Sustainable Science & Technology
Gabrielli do Livramento Goncalves, Walter Leal Filho, Samara da Silva Neiva, Andre Borchardt Deggau, Manoela de Oliveira Veras, Flavio Ceci, Mauricio Andrade de Lima, Jose Baltazar Salgueirinho Osorio de Andrade Guerra
Summary: The Fourth Industrial Revolution will impact various aspects of sustainable cities, including job creation, industries, innovation, environmental preservation, community involvement, and accessibility. Policymakers will face both opportunities and challenges in adapting to these changes.
Article
Green & Sustainable Science & Technology
David Mhlanga
Summary: Stakeholder capitalism is gaining traction in the Fourth Industrial Revolution, with the World Economic Forum and Business Roundtable endorsing it as a key principle guiding corporate management. While embracing stakeholder capitalism can lead to sustainable development, there are several challenges that need to be addressed, such as balancing stakeholder expectations and defining clear guidelines and theoretical foundation.
Review
Plant Sciences
Mohd Fadhli Hamdan, Siti Nurfadhlina Mohd Noor, Nazrin Abd-Aziz, Teen-Lee Pua, Boon Chin Tan
Summary: The evolution of technological applications in agriculture, including genetic engineering and genome editing techniques, is crucial for increasing crop yields and quality, addressing climate change and rising food demand. However, the development and application of these modern technologies also face challenges in regulation and standardization.
Article
Green & Sustainable Science & Technology
Love O. David, Nnamdi I. Nwulu, Clinton O. Aigbavboa, Omoseni O. Adepoju
Summary: This study evaluates the application of Fourth Industrial Revolution (4IR) technologies on the water, energy, and food (WEF) nexus and finds that most technologies have not been integrated, except for the Internet of Things and Big Data analytics. The study highlights the importance of data collection, accuracy, and analysis for the security of the WEF nexus.
JOURNAL OF CLEANER PRODUCTION
(2022)
Review
Food Science & Technology
Oluwatobi Esther Ayiti, Olubukola Oluranti Babalola
Summary: This review discusses the role of maize in the industrial revolution, progress toward sustainable production, and the potential of nitrifying bacteria and archaea to achieve sustainable intensification.
FRONTIERS IN SUSTAINABLE FOOD SYSTEMS
(2022)
Article
Computer Science, Information Systems
Wynand Lambrechts, Saurabh Sinha, Sarah Mosoetsa
Summary: Data gathering and information processing have reached an unprecedented level today, with the help of technologies like artificial intelligence, machine learning, and cognitive computing. It is crucial for digital algorithms to be aligned with human value systems and ethics to prevent exploitation of data sources. This approach ensures that technology serves society in a way that is ethical and respectful.
Article
Business
Gang-Gao Hu
Summary: The study aims to investigate the determinants of technological innovation in BRICS countries, the mediating role of human capital in the relationship between spillovers and technological progress, and the impact on total technological innovation. Results indicate that an increase in GDP, human capital, R&D expenditures, and FDI spillovers contribute to technological innovation in BRICS economies.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Review
Plant Sciences
Johan Rodriguez Melo, Florencia Mammarella, Federico Ariel
Summary: The increasing world population and global warming have significantly impacted agriculture, leading to the emergence of new pests and pathogens that threaten crop productivity. To address this, the scientific community is urgently developing innovative solutions, such as using RNA-based technologies as an alternative to synthetic pesticides. The stabilization and delivery of RNA through nanotechnology is crucial for its versatile applications in sustainable agriculture. This eco-friendly approach can also help plants adapt to extreme environmental conditions in the context of climate change.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Food Science & Technology
Gheorghe Adrian Martau, Lavinia-Florina Calinoiu, Dan Cristian Vodnar
Summary: The production of bio-vanillin has significant advantages over other methods, as it meets modern consumer trends, supports industrial production, and is considered natural and non-toxic. Biotechnological approaches offer a promising route for achieving high efficiency and sustainable production.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2021)
Article
Business
Ya Cheng, Usama Awan, Shabbir Ahmad, Zhixiong Tan
Summary: The deteriorating environmental quality poses a serious threat to life on earth, and China needs to formulate policies to reduce emissions and promote an energy-efficient system, as well as clarify the responsibilities at different levels of government to successfully achieve low carbon emissions and energy-saving expenditure targets.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2021)
Article
Chemistry, Inorganic & Nuclear
Thiruvenkataswamy Saranya, Sennimalai Ramya, Krishnamoorthy Kavithaa, Manickam Paulpandi, Yong-Pil Cheon, Sureshbabu Harysh Winster, Vellingiri Balachandar, Arul Narayanasamy
Summary: This study successfully synthesized selenium nanoparticles with antioxidant, antibacterial, and anticancer activities through green synthesis using the fruit extract of Solanum nigrum. The synthesized nanoparticles were characterized and confirmed to possess significant antioxidant, antibacterial, and anticancer properties.
JOURNAL OF CLUSTER SCIENCE
(2023)
Article
Medicine, Research & Experimental
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Pragya Bradu, Aarthi Sukumar, Megha Patil, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, Alex George, Raja Ganesan
Summary: This review provides a detailed study on pancreatic cancer and its association with different types of cancer related to diabetes. It discusses the combination of anti-diabetic drugs with other anti-cancer drugs and phytochemicals for the prevention and treatment of the disease. The migration and development of pancreatic cancer stem cells (CSCs) are also discussed. Additionally, it explores the mechanisms of diabetes development that enhance the proliferation of pancreatic CSCs, such as increased IGF factor levels, epigenetic modifications, DNA damage, and lifestyle factors like obesity and inflammation.
Review
Green & Sustainable Science & Technology
Anirban Goutam Mukherjee, Kaviyarasi Renu, Abilash Valsala Gopalakrishnan, Vishnu Priya Veeraraghavan, Sathishkumar Vinayagam, Soraya Paz-Montelongo, Abhijit Dey, Balachandar Vellingiri, Alex George, Harishkumar Madhyastha, Raja Ganesan
Summary: Heavy metal and metalloid poisoning in the environment and food, such as cadmium, lead, mercury, tin, manganese, aluminium, arsenic, antimony, and selenium, poses a severe threat to human health and ecological system. Accurate detection of even trace quantities of these toxic elements is of utmost importance to understand their risk. Several traditional and advanced technologies, including atomic absorption spectrometry (AAS), spectrofluorimetry, inductively coupled plasma spectrometry, e-tongues, electrochemical aptasensors, Raman spectroscopy, and fluorescence sensors, have proven highly beneficial in quantifying these elements in food and dietary supplements.
Review
Biochemistry & Molecular Biology
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Sandra Kannampuzha, Reshma Murali, Arunraj Namachivayam, Raja Ganesan, Abhijit Dey, Achsha Babu, Kaviyarasi Renu, Balachandar Vellingiri, Gnanasambandan Ramanathan, C. George Priya Doss, Nehal Elsherbiny, Amira M. Elsherbini, Alsamman M. Alsamman, Hatem Zayed, Abilash Valsala Gopalakrishnan
Summary: Polycystic ovarian syndrome (PCOS) is a complex endocrine and metabolic condition that affects women's reproductive health. The causes of PCOS are still unknown, but alterations in gut microbiota composition and disruptions in secondary bile acid production appear to be involved. PCOS is closely related to both enteric and vaginal bacteria, and patients with PCOS have changed microbiome compositions and decreased microbial diversity. The gut microbiota can interact with the environment to improve metabolic and immunological function, but dysbiosis in the gut microbiome may contribute to inflammation and insulin resistance in PCOS.
Review
Biochemistry & Molecular Biology
Uddesh Ramesh Wanjari, Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan, Reshma Murali, Abhijit Dey, Balachandar Vellingiri, Raja Ganesan
Summary: Prostate cancer (PCa) is the leading cause of mortality in men, with unclear pathophysiological factors. PCa cells adopt abnormal lipid signaling and metabolism to gain protection. They modify metabolism in response to excessive nutrient intake, facilitating disease progression. Metabolic syndrome (MetS) is closely linked to carcinogenesis in PCa, exacerbating disease severity. Changes in mitochondrial metabolism are hypothesized to contribute to PCa onset. Examining the metabolome of prostate tissue can help study specific alterations in PCa progression. Additional epidemiological research is needed to determine the relationship between MetS and PCa due to inconsistent initial findings. Multiple risk factors, including MetS, are correlated with PCa progression. This review focuses on analyzing and evaluating metabolic changes in PCa, assessing the impact of metabolic abnormalities on disease aggressiveness and metabolism.
Review
Immunology
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Sandra Kannampuzha, Reshma Murali, Arunraj Namachivayam, Raja Ganesan, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, D. S. Prabakaran
Summary: COVID-19 has potential detrimental effects on the male reproductive system, with evidence suggesting sexual transmission of the virus. Testicular cells express a high level of ACE2 receptor, facilitating viral entry. COVID-19 may lead to testicular dysfunction and oxidative stress. This study highlights the impact of COVID-19 on male reproductive system and raises unanswered questions about its link to men's health and fertility.
Review
Immunology
Reshma Murali, Uddesh Ramesh Wanjari, Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan, Sandra Kannampuzha, Arunraj Namachivayam, Harishkumar Madhyastha, Kaviyarasi Renu, Raja Ganesan
Summary: The novel SARS-CoV-2 virus causes COVID-19, a respiratory disorder, and has been found to result in kidney injuries, particularly kidney tubular injuries. Infection with the virus not only leads to new kidney disease, but also increases treatment difficulties and mortality rates in individuals with preexisting kidney diseases. Urinary metabolites from various metabolic pathways can be used to differentiate between COVID-19 patients with and without acute kidney injury (AKI). Metabolomics is expected to play a significant role in predicting outcomes for COVID-19 patients with kidney disease as the understanding of metabolic profiles expands rapidly.
Review
Immunology
Sandra Kannampuzha, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Reshma Murali, Arunraj Namachivayam, Kaviyarasi Renu, Abhijit Dey, Balachandar Vellingiri, Harishkumar Madhyastha, Raja Ganesan
Summary: Lung cancer is a major cause of cancer-related deaths. The altered metabolism of cancer cells results in changes in metabolite concentrations, which can be used to identify distinct metabolic patterns for cancer detection. Understanding and analyzing the variations in metabolites can provide early biomarkers and insights into the progression and type of lung cancer.
Review
Biochemistry & Molecular Biology
Hafiza Padinharayil, Jinsu Varghese, Mithun Chacko John, Golgodu Krishnamurthy Rajanikant, Cornelia M. Wilson, Minnatallah Al-Yozbaki, Kaviyarasi Renu, Saikat Dewanjee, Rupa Sanyal, Abhijit Dey, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Alex George
Summary: Continuous revision of the histologic and stage-wise classification of lung cancer by the World Health Organization (WHO) supports therapeutic advances and accurate diagnosis. Cancer epidemiologic data provide helpful information for cancer prevention and management. Global cancer mortality projections indicate that cancer will become the leading cause of death, particularly non-small cell lung cancer (NSCLC) which accounts for a significant portion of lung cancers. Early diagnosis and proper management play crucial roles in NSCLC therapies. Advanced techniques, such as immune checkpoint inhibitors (ICIs) and targeted molecular therapies, have improved the treatment of late-stage NSCLC. However, the improvement of cancer biomarkers and the development of prospective studies are needed for better therapeutic outcomes.
Review
Oncology
Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan
Summary: The Nrf2 protein plays a crucial role in protecting cells and tissues by preserving tissue integrity and safeguarding against various types of stress. It has potential implications in cancer prevention and treatment.
Review
Oncology
Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan, Rama Jayaraj, Raja Ganesan, Kaviyarasi Renu, Balachandar Vellingiri, Abhijit Dey, Mohamudha Parveen
Summary: Despite medical advancements in surgery and adjuvant therapies, brain tumors continue to be a leading cause of cancer-related death and illness in both children and adults. Metabolomics, the comprehensive analysis of small molecules, has emerged as a promising area for personalized medicine and drug discovery, offering insights into cellular activity and cancer biology. Advanced analytical techniques like nuclear magnetic resonance spectroscopy (MRS) and mass spectrometry (MS) allow for high-throughput analysis, enabling the study of human brain tumor metabolomics.
Review
Oncology
Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Abilash Valsala Gopalakrishnan, Rama Jayaraj, Ramkumar Katturajan, Sandra Kannampuzha, Reshma Murali, Arunraj Namachivayam, Sabina Evan Prince, Balachandar Vellingiri, Abhijit Dey, Kaviyarasi Renu
Summary: Cancer and related diseases rank second in global causes of death. Human papillomavirus (HPV) is an infectious agent primarily transmitted through sexual contact and is associated with various malignancies in both sexes. HPV is strongly linked to cervical cancer and also plays a role in head and neck cancer, particularly oropharyngeal cancer. Additionally, certain HPV-related cancers such as vaginal, vulvar, penile, and anal cancers are associated with the anogenital region. Extensive research has focused on HPV16 and HPV18 due to their significant carcinogenic potential, with the viral genes E6 and E7 identified as key players in cellular transformation and cancer progression. This review highlights the different types of cancers caused by HPV and discusses the signaling cascades involved.
Review
Oncology
Anirban Goutam Mukherjee, Abilash Valsala Gopalakrishnan
Summary: Male-specific reproductive disorders and cancers, including prostate cancer, have seen a significant increase in recent years, posing a major public health issue. Both genetic and epigenetic modifications play a role in the development and progression of prostate cancer, while the underlying cause is still unknown. Male infertility, believed to affect a significant portion of the male population, is also linked to prostate cancer. This article provides an overview of prostate cancer and spermatogenic abnormalities, investigating the underlying reasons, risk factors, and biological mechanisms contributing to the link between male infertility and prostate cancer.
Review
Oncology
Soumik Das, Achsha Babu, Tamma Medha, Gnanasambandan Ramanathan, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Reshma Murali, Sandra Kannampuzha, Abilash Valsala Gopalakrishnan, Kaviyarasi Renu, Debottam Sinha, C. George Priya Doss
Summary: Cervical cancer is a leading cause of cancer death among women, with a majority of deaths occurring in developing regions. Human papillomavirus is the main cause of cervical cancer, and the prophylactic vaccine is expected to eliminate HPV-associated cervical cancer. However, patients with advanced-stage cervical cancer have a high recurrence rate and drug resistance remains a challenge. Understanding the mechanisms of drug resistance and developing novel strategies is important for improving the quality of care for cancer patients.
Review
Oncology
Sandra Kannampuzha, Reshma Murali, Abilash Valsala Gopalakrishnan, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Arunraj Namachivayam, Alex George, Abhijit Dey, Balachandar Vellingiri
Summary: Cancer poses a significant threat to human life worldwide, and there is an urgent need for the discovery and application of novel biomolecules in cancer treatment. Precision medicine relies on targeted therapies, and the understanding of proteins has enabled researchers to develop more effective treatments. There is a diversification of targets and advancements in therapeutic antibodies and biotechnology that have expanded the possibilities of curative treatments. It is important to fully understand the mechanisms and significance of these novel drug targets and strategies to advance targeted cancer therapies.
