Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity
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Title
Impaired V-ATPase leads to increased lysosomal pH, results in disrupted lysosomal degradation and autophagic flux blockage, contributes to fluoride-induced developmental neurotoxicity
Authors
Keywords
Fluoride, V-ATPase, Lysosomal pH, Lysosomal degradation capacity, Developmental neurotoxicity
Journal
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Volume 236, Issue -, Pages 113500
Publisher
Elsevier BV
Online
2022-04-12
DOI
10.1016/j.ecoenv.2022.113500
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