Coordinated activities of Myosin Vb isoforms and mTOR signaling regulate epithelial cell morphology during development

Grhl3 promotes retention of epidermal cells under endocytic stress to maintain epidermal architecture in zebrafish

(2021) Mandar Phatak et al.   PLoS Genetics

Defects in COG-Mediated Golgi Trafficking Alter Endo-Lysosomal System in Human Cells

(2019) Zinia D’Souza et al.   Frontiers in Cell and Developmental Biology

Loss of myosin Vb promotes apical bulk endocytosis in neonatal enterocytes

(2019) Amy C. Engevik et al.   JOURNAL OF CELL BIOLOGY

Scutoids are a geometrical solution to three-dimensional packing of epithelia

(2018) Pedro Gómez-Gálvez et al.   Nature Communications

Cell-size distribution in epithelial tissue formation and homeostasis

(2017) Alberto Puliafito et al.   Journal of the Royal Society Interface

Fatty acid synthase cooperates with protrudin to facilitate membrane outgrowth of cellular protrusions

(2017) Chuanling Zhang et al.   Scientific Reports

Intracellular Golgi Complex organization reveals tissue specific polarity during zebrafish embryogenesis

(2016) Diane S. Sepich et al.   DEVELOPMENTAL DYNAMICS

Srebp2: A master regulator of sterol and fatty acid synthesis

(2016) Blair B. Madison   JOURNAL OF LIPID RESEARCH

The zebrafish goosepimples/myosin Vb mutant exhibits cellular attributes of human microvillus inclusion disease

(2016) Jaydeep Sidhaye et al.   MECHANISMS OF DEVELOPMENT

Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3

(2015) Georg F. Vogel et al.   JOURNAL OF CELL BIOLOGY

Kidney growth and hypertrophy: the role of mTOR and vesicle trafficking

(2015) Qais Al-Awqati   JOURNAL OF CLINICAL INVESTIGATION

Unjamming and cell shape in the asthmatic airway epithelium

(2015) Jin-Ah Park et al.   NATURE MATERIALS

On being the right (cell) size

(2015) M. B. Ginzberg et al.   SCIENCE

Target of Rapamycin Complex 2 regulates cell growth via Myc in Drosophila

(2015) Ying Kuo et al.   Scientific Reports

De novo fatty acid synthesis at the mitotic exit is required to complete cellular division

(2014) Natalia Scaglia et al.   CELL CYCLE

Recapitulation of morphogenetic cell shape changes enables wound re-epithelialisation

(2014) William Razzell et al.   DEVELOPMENT

Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease

(2014) Byron C. Knowles et al.   JOURNAL OF CLINICAL INVESTIGATION

α-lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects

(2014) Marta Fernández-Galilea et al.   Obesity

The mTOR Inhibitor Rapamycin Synergizes with a Fatty Acid Synthase Inhibitor to Induce Cytotoxicity in ER/HER2-Positive Breast Cancer Cells

(2014) Chen Yan et al.   PLoS One

Myosin Vb Mediated Plasma Membrane Homeostasis Regulates Peridermal Cell Size and Maintains Tissue Homeostasis in the Zebrafish Epidermis

(2014) Sonal et al.   PLoS Genetics

The Regulation of Cell Size

(2013) Alison C. Lloyd   CELL

Polyploidization and Cell Fusion Contribute to Wound Healing in the Adult Drosophila Epithelium

(2013) Vicki P. Losick et al.   CURRENT BIOLOGY

The mechanical anisotropy in a tissue promotes ordering in hexagonal cell packing

(2013) Kaoru Sugimura et al.   DEVELOPMENT

Pou5f1-Dependent EGF Expression Controls E-Cadherin Endocytosis, Cell Adhesion, and Zebrafish Epiboly Movements

(2013) Sungmin Song et al.   DEVELOPMENTAL CELL

Tissue Repair through Cell Competition and Compensatory Cellular Hypertrophy in Postmitotic Epithelia

(2013) Yoichiro Tamori et al.   DEVELOPMENTAL CELL

A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells

(2013) Puneet Khandelwal et al.   MOLECULAR BIOLOGY OF THE CELL

Analysis Tool Web Services from the EMBL-EBI

(2013) Hamish McWilliam et al.   NUCLEIC ACIDS RESEARCH

Theory of epithelial sheet morphology in three dimensions

(2013) E. Hannezo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compensatory cellular hypertrophy: the other strategy for tissue homeostasis

(2013) Yoichiro Tamori et al.   TRENDS IN CELL BIOLOGY

Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon development

(2013) Yang Liu et al.   Nature Communications

Organ Size Control by Hippo and TOR Pathways

(2012) Karen Tumaneng et al.   CURRENT BIOLOGY

Localization and Substrate Selectivity of Sea Urchin Multidrug (MDR) Efflux Transporters

(2012) Tufan Gökirmak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zhenqing recipe alleviates diabetic nephropathy in experimental type 2 diabetic rats through suppression of SREBP-1c

(2012) Xiuying Wen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis

(2012) Marlen Knobloch et al.   NATURE

Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli

(2012) Z. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

The integral role of mTOR in lipid metabolism

(2011) Ghada A. Soliman   CELL CYCLE

Generation of Rab-based transgenic lines for in vivo studies of endosome biology in zebrafish

(2011) Brian S. Clark et al.   DEVELOPMENTAL DYNAMICS

Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization

(2011) J. T. Roland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis and Biosynthetic Trafficking of Membrane Lipids

(2011) T. Blom et al.   Cold Spring Harbor Perspectives in Biology

Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model

(2010) Frank M. Ruemmele et al.   HUMAN MUTATION

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

(2010) Qingsong Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apical trafficking in epithelial cells: signals, clusters and motors

(2009) O. A. Weisz et al.   JOURNAL OF CELL SCIENCE

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Rictor/TORC2 Regulates Caenorhabditis elegans Fat Storage, Body Size, and Development through sgk-1

(2009) Kevin T Jones et al.   PLOS BIOLOGY

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Alternative Splicing in Class V Myosins Determines Association with Rab10

(2008) Joseph T. Roland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wheat germ agglutinin stains dispersed post-golgi vesicles after treatment with the cytokinesis inhibitor psychosine

(2008) Takayuki Kanazawa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity

(2008) Thomas Müller et al.   NATURE GENETICS