Free Cholesterol Bioavailability and Atherosclerosis

Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis

(2021) Huan Tao et al.   JOURNAL OF CLINICAL INVESTIGATION

The cellular function of SCAP in metabolic signaling

(2020) Sun Hee Lee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

SR-B1 drives endothelial cell LDL transcytosis via DOCK4 to promote atherosclerosis

(2019) Linzhang Huang et al.   NATURE

Rethinking reverse cholesterol transport and dysfunctional high-density lipoproteins

(2018) Baiba K. Gillard et al.   Journal of Clinical Lipidology

ApoM-S1P Modulates Ox-LDL-Induced Inflammation Through the PI3K/Akt Signaling Pathway in HUVECs

(2018) Zhi Zheng et al.   INFLAMMATION

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

(2018) Louise H. Wong et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intracellular Cholesterol Transport by Sterol Transfer Proteins at Membrane Contact Sites

(2018) Jie Luo et al.   TRENDS IN BIOCHEMICAL SCIENCES

NMR Structure of the C-Terminal Transmembrane Domain of the HDL Receptor, SR-BI, and a Functionally Relevant Leucine Zipper Motif

(2017) Alexandra C. Chadwick et al.   STRUCTURE

SR-BI: A Multifunctional Receptor in Cholesterol Homeostasis and Atherosclerosis

(2017) MacRae F. Linton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1

(2017) Karen Y. Fung et al.   Frontiers in Physiology

Cholesterol Biosynthesis: A Mechanistic Overview

(2016) Nuno M. F. S. A. Cerqueira et al.   BIOCHEMISTRY

Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion

(2016) Lily Jakulj et al.   Cell Metabolism

The role of cholesterol in membrane fusion

(2016) Sung-Tae Yang et al.   CHEMISTRY AND PHYSICS OF LIPIDS

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)CLINICAL PERSPECTIVE

(2016) Xiaoping Yang et al.   Circulation-Cardiovascular Genetics

S1P in HDL promotes interaction between SR-BI and S1PR1 and activates S1PR1-mediated biological functions: calcium flux and S1PR1 internalization

(2016) Mi-Hye Lee et al.   JOURNAL OF LIPID RESEARCH

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease

(2016) Paolo Zanoni et al.   SCIENCE

SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)CLINICAL PERSPECTIVE

(2016) Xiaoping Yang et al.   Circulation-Cardiovascular Genetics

Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis

(2015) Huan Tao et al.   JOURNAL OF LIPID RESEARCH

A new model of reverse cholesterol transport: enTICEing strategies to stimulate intestinal cholesterol excretion

(2015) Ryan E. Temel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice

(2015) Boris L. Vaisman et al.   Biomed Research International

The Effects of Diet on Occlusive Coronary Artery Atherosclerosis and Myocardial Infarction in Scavenger Receptor Class B, Type 1/Low-Density Lipoprotein Receptor Double Knockout Mice

(2014) Mark Fuller et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HDL and cardiovascular disease

(2014) Daniel J Rader et al.   LANCET

Key role for scavenger receptor B-I in the integrative physiology of host defense during bacterial pneumonia

(2014) K M Gowdy et al.   Mucosal Immunology

Scavenger receptor class B type I and immune dysfunctions

(2014) Zhong Zheng et al.   Current Opinion in Endocrinology Diabetes and Obesity

Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

(2013) Cédric Le May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice

(2013) Arne Dikkers et al.   HEPATOLOGY

Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice

(2013) Kanwardeep S. Bura et al.   JOURNAL OF LIPID RESEARCH

How Do Elevated Triglycerides and Low HDL-Cholesterol Affect Inflammation and Atherothrombosis?

(2013) Francine K. Welty   Current Cardiology Reports

Cholesterol Efflux and Atheroprotection

(2012) Robert S. Rosenson et al.   CIRCULATION

Biliary and nonbiliary contributions to reverse cholesterol transport

(2012) Ryan E. Temel et al.   CURRENT OPINION IN LIPIDOLOGY

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Is it time to revise the HDL cholesterol hypothesis?

(2012) Daniel J Rader et al.   NATURE MEDICINE

Heartache and heartbreak—the link between depression and cardiovascular disease

(2012) Charles B. Nemeroff et al.   Nature Reviews Cardiology

Effects of Dalcetrapib in Patients with a Recent Acute Coronary Syndrome

(2012) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI

(2011) Martin F. Brodde et al.   ATHEROSCLEROSIS

HDL scavenger receptor class B type I and platelet function

(2011) Jerzy-Roch Nofer et al.   CURRENT OPINION IN LIPIDOLOGY

Smith–Lemli–Opitz syndrome

(2011) Andrea E. DeBarber et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

PON-dering differences in HDL function in coronary artery disease

(2011) Chieko Mineo et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I diabetes mellitus decreases in vivo macrophage-to-feces reverse cholesterol transport despite increased biliary sterol secretion in mice

(2011) Jan Freark de Boer et al.   JOURNAL OF LIPID RESEARCH

Linking lipids to Alzheimer's disease: cholesterol and beyond

(2011) Gilbert Di Paolo et al.   NATURE REVIEWS NEUROSCIENCE

A Genetic Variant of the Scavenger Receptor BI in Humans

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Variant of the Scavenger Receptor BI in Humans

(2011) Menno Vergeer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways

(2010) Aishah Al-Jarallah et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Biliary Sterol Secretion Is Not Required for Macrophage Reverse Cholesterol Transport

(2010) Ryan E. Temel et al.   Cell Metabolism

Niemann–Pick type C pathogenesis and treatment: from statins to sugars

(2010) Moneek Madra et al.   Clinical Lipidology

Sterol Regulatory Element Binding Proteins in Fungi: Hypoxic Transcription Factors Linked to Pathogenesis

(2010) Clara M. Bien et al.   EUKARYOTIC CELL

Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice

(2010) Lily Jakulj et al.   FEBS LETTERS

Biliary Sterol Secretion Is Required for Functional In Vivo Reverse Cholesterol Transport in Mice

(2010) Niels Nijstad et al.   GASTROENTEROLOGY

ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis

(2010) Lily Jakulj et al.   JOURNAL OF LIPID RESEARCH

Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses

(2009) Laurent Yvan-Charvet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sphingosine-1-phosphate as a mediator of high-density lipoprotein effects in cardiovascular protection

(2009) K. Sattler et al.   CARDIOVASCULAR RESEARCH

High-Density Lipoprotein Transport Through Aortic Endothelial Cells Involves Scavenger Receptor BI and ATP-Binding Cassette Transporter G1

(2009) Lucia Rohrer et al.   CIRCULATION RESEARCH

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

(2009) M. J. Chapman et al.   EUROPEAN HEART JOURNAL

Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice

(2009) Harmen Wiersma et al.   HEPATOLOGY

Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus

(2009) Lars Fester et al.   HIPPOCAMPUS

Activation of the Liver X Receptor Stimulates Trans-intestinal Excretion of Plasma Cholesterol

(2009) Jelske N. van der Veen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered cholesterol and fatty acid metabolism in Huntington disease

(2009) Robert C. Block et al.   Journal of Clinical Lipidology

The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene

(2009) M. Junyent et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Regulation of direct transintestinal cholesterol excretion in mice

(2008) Astrid E. van der Velde et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Targeted Depletion of Hepatic ACAT2-driven Cholesterol Esterification Reveals a Non-biliary Route for Fecal Neutral Sterol Loss

(2008) J. Mark Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of reverse cholesterol transport in animals and humans and relationship to atherosclerosis

(2008) Daniel J. Rader et al.   JOURNAL OF LIPID RESEARCH

Lipid rafts, cholesterol, and the brain

(2008) Zeljka Korade et al.   NEUROPHARMACOLOGY