The regulatory role of eosinophils in viral, bacterial, and fungal infections

Treatment Challenges in Severe Eosinophilic Asthma: Differential Response to Anti-IL-5 and Anti-IL-5R Therapy

(2021) Agamemnon Bakakos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Strategies for Choosing a Biologic for Your Allergy or Asthma Patient

(2021) Tara Saco et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

Biologic Therapies for Allergic Rhinitis and Nasal Polyposis

(2021) Bob Geng et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Eosinophils and Bacteria, the Beginning of a Story

(2021) Edna Ondari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Eosinophils in Health and Disease: A State-of-the-Art Review

(2021) Michael E. Wechsler et al.   MAYO CLINIC PROCEEDINGS

Eosinophils and helminth infection: protective or pathogenic?

(2021) E. Mitre et al.   Seminars in Immunopathology

Human Eosinophils Reduce Viral Titer, Secrete IL-8, and Increase RIG-I Expression in Response to Influenza A H1N1 pdm09

(2021) Armando S. Flores-Torres et al.   VIRAL IMMUNOLOGY

Protective effects of eosinophils against COVID-19: More than an ACE(2) in the hole?

(2021) Matthew G. Drake et al.   Journal of Allergy and Clinical Immunology-In Practice

AVEXIS technology identifies novel platelet-leukocyte binding partners including CD148-CD300a

(2021) Ruben Barroso et al.   Blood Advances

Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan. A Retrospective Observational Study

(2020) Yingzhen Du et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Structure of mouse coronavirus spike protein complexed with receptor reveals mechanism for viral entry

(2020) Jian Shang et al.   PLoS Pathogens

COVID-19, asthma, and biological therapies: What we need to know

(2020) Mário Morais-Almeida et al.   World Allergy Organization Journal

Immunoglobulin A and the microbiome

(2020) Yi Yang et al.   CURRENT OPINION IN MICROBIOLOGY

Antibacterial antibiotic-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a literature review

(2020) Shiva Sharifzadeh et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities

(2019) Chamutal Gur et al.   OncoImmunology

Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF

(2019) Matthew L. Brewer et al.   Journal of Oral Microbiology

Contribution of Fcγ Receptor-Mediated Immunity to the Pathogenesis Caused by the Human Respiratory Syncytial Virus

(2019) Orlando A. Acevedo et al.   Frontiers in Cellular and Infection Microbiology

Siglec-7 on peripheral blood eosinophils: Surface expression and function

(2019) Fanny Legrand et al.   ALLERGY

GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation

(2019) Michael Dougan et al.   IMMUNITY

Adverse events of benralizumab in moderate to severe eosinophilic asthma

(2019) Wanshu Liu et al.   MEDICINE

Charcot-Leyden Crystals in Eosinophilic Inflammation: Active Cytolysis Leads to Crystal Formation

(2019) Shigeharu Ueki et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Gold nanoparticle‐adjuvanted S protein induces a strong antigen‐specific IgG response against severe acute respiratory syndrome‐related coronavirus infection, but fails to induce protective antibodies and limit eosinophilic infiltration in lungs

(2019) Hanako Sekimukai et al.   MICROBIOLOGY AND IMMUNOLOGY

Unaltered Fungal Burden and Lethality in Human CEACAM1-Transgenic Mice During Candida albicans Dissemination and Systemic Infection

(2019) Esther Klaile et al.   Frontiers in Microbiology

Eosinophils release extracellular DNA traps in response to Aspergillus fumigatus

(2018) Valdirene S. Muniz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation

(2018) Isabelle C. Arnold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Contemporary understanding of the secretory granules in human eosinophils

(2018) Rossana C. N. Melo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Eosinophils in fungal diseases: An overview

(2018) Rodrigo T. Figueiredo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Antifungal immune responses: emerging host–pathogen interactions and translational implications

(2018) Vinod Kumar et al.   Genome Medicine

Anti-IL5 in Mild Asthma Alters Rhinovirus-Induced Macrophage, B Cell and Neutrophil Responses (MATERIAL): A Placebo-Controlled, Double-Blind Study

(2018) Yanaika S. Sabogal Piñeros et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Charcot-Leyden crystal formation is closely associated with eosinophil extracellular trap cell death

(2018) Shigeharu Ueki et al.   BLOOD

CD300 receptor family in viral infections

(2018) Joana Vitallé et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Assessment of the long-term safety of mepolizumab and durability of clinical response in patients with severe eosinophilic asthma

(2018) Sumita Khatri et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus

(2017) Amali E. Samarasinghe et al.   JOURNAL OF IMMUNOLOGY

Granulocytes: New Members of the Antigen-Presenting Cell Family

(2017) Ang Lin et al.   Frontiers in Immunology

sCD48 is anti-inflammatory inStaphylococcus aureusEnterotoxin B-induced eosinophilic inflammation

(2016) R. S. Gangwar et al.   ALLERGY

Human and Mouse Eosinophils Have Antiviral Activity against Parainfluenza Virus

(2016) Matthew G. Drake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Activation of toll-like receptor signaling pathways leading to nitric oxide-mediated antiviral responses

(2016) Mohamed Sarjoon Abdul-Cader et al.   ARCHIVES OF VIROLOGY

Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders

(2016) Gilda Varricchi et al.   Current Opinion in Allergy and Clinical Immunology

Eosinophil extracellular trap cell death–derived DNA traps: Their presence in secretions and functional attributes

(2016) Shigeharu Ueki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lung-resident eosinophils represent a distinct regulatory eosinophil subset

(2016) Claire Mesnil et al.   JOURNAL OF CLINICAL INVESTIGATION

Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine

(2016) Peter Valent et al.   Journal of Innate Immunity

Parainfluenza Virus Infection

(2016) Angela Branche et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Eosinophils in Helminth Infection: Defenders and Dupes

(2016) Lu Huang et al.   TRENDS IN PARASITOLOGY

Microbiota-Regulated IL-25 Increases Eosinophil Number to Provide Protection during Clostridium difficile Infection

(2016) Erica L. Buonomo et al.   Cell Reports

Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis

(2016) Ian D Pavord et al.   Lancet Respiratory Medicine

The era of the immunoglobulin A Fc receptor FcαRI; its function and potential as target in disease

(2015) Esil Aleyd et al.   IMMUNOLOGICAL REVIEWS

Eosinophilia in Infectious Diseases

(2015) Elise M. O’Connell et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

IL-1β in eosinophil-mediated small intestinal homeostasis and IgA production

(2015) Y Jung et al.   Mucosal Immunology

The CD48 receptor mediatesStaphylococcus aureushuman and murine eosinophil activation

(2014) Y. Minai-Fleminger et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo

(2014) Derek K. Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Innate Antifungal Immunity of Human Eosinophils Mediated by a  2 Integrin, CD11b

(2014) J. Yoon et al.   JOURNAL OF IMMUNOLOGY

IgA Enhances NETosis and Release of Neutrophil Extracellular Traps by Polymorphonuclear Cells via Fc  Receptor I

(2014) E. Aleyd et al.   JOURNAL OF IMMUNOLOGY

Eosinophil Deficiency Compromises Lung Defense against Aspergillus fumigatus

(2013) Lauren M. Lilly et al.   INFECTION AND IMMUNITY

Fc gamma receptors in respiratory syncytial virus infections: implications for innate immunity

(2013) Jop Jans et al.   REVIEWS IN MEDICAL VIROLOGY

Inhaled corticosteroids in COPD and the risk of serious pneumonia

(2013) Samy Suissa et al.   THORAX

Pattern-recognition receptors in human eosinophils

(2012) Anne Månsson Kvarnhammar et al.   IMMUNOLOGY

Staphylococcus aureus directly activates eosinophils via platelet-activating factor receptor

(2012) Koa Hosoki et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Staphylococcus aureus Induces Eosinophil Cell Death Mediated by α-hemolysin

(2012) Lynne R. Prince et al.   PLoS One

The Soluble Serum Protein Gas6 Bridges Virion Envelope Phosphatidylserine to the TAM Receptor Tyrosine Kinase Axl to Mediate Viral Entry

(2011) Kouki Morizono et al.   Cell Host & Microbe

Eosinophils: multifaceted biological properties and roles in health and disease

(2011) Hirohito Kita   IMMUNOLOGICAL REVIEWS

Structure and function relationships in IgA

(2011) J M Woof et al.   Mucosal Immunology

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Increased Eosinophilic Cationic Protein in Nasal Fluid in Hospitalized Wheezy Infants with RSV Infection

(2011) Naoko Okamoto et al.   ALLERGOLOGY INTERNATIONAL

Phagocytosis of heat-killed Staphylococcus aureus by eosinophils: comparison with neutrophils

(2010) YASUKO HATANO et al.   APMIS

Murine lung eosinophil activation and chemokine production in allergic airway inflammation

(2010) C Edward Rose et al.   Cellular & Molecular Immunology

Eosinophil Survival and Apoptosis in Health and Disease

(2010) Yong Mean Park et al.   Allergy Asthma & Immunology Research

Pneumoviruses infect eosinophils and elicit MyD88-dependent release of chemoattractant cytokines and interleukin-6

(2009) K. D. Dyer et al.   BLOOD

Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors

(2009) B. S. Bochner   CLINICAL AND EXPERIMENTAL ALLERGY

Recognition of Fungal Protease Activities Induces Cellular Activation and Eosinophil-Derived Neurotoxin Release in Human Eosinophils

(2009) Y. Matsuwaki et al.   JOURNAL OF IMMUNOLOGY

TLR2-dependent eosinophil interactions with mycobacteria: role of  -defensins

(2008) V. Driss et al.   BLOOD

Eosinophils: Biological Properties and Role in Health and Disease

(2008) SIMON P. HOGAN et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Eosinophils and their interactions with respiratory virus pathogens

(2008) Helene F. Rosenberg et al.   IMMUNOLOGIC RESEARCH

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE