The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer
Authors
Keywords
microbial metabolite, commensal microbiota, antitumor immunity, trimethylamine N-oxide, triple-negative breast cancer, pyroptosis, immunotherapy
Journal
Cell Metabolism
Volume 34, Issue 4, Pages 581-594.e8
Publisher
Elsevier BV
Online
2022-03-11
DOI
10.1016/j.cmet.2022.02.010
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity
- (2021) Yao He et al. Cell Metabolism
- Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer
- (2021) Maik Luu et al. Nature Communications
- Gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice
- (2020) Kunpeng Wu et al. BLOOD
- Gasdermin E suppresses tumour growth by activating anti-tumour immunity
- (2020) Zhibin Zhang et al. NATURE
- The human tumor microbiome is composed of tumor type–specific intracellular bacteria
- (2020) Deborah Nejman et al. SCIENCE
- Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy
- (2020) Lukas F. Mager et al. SCIENCE
- Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria
- (2020) José Carlos Santos et al. Nature Communications
- IL-18: throwing off the shackles to boost anti-tumor immunity
- (2020) Karen O. Dixon et al. CELL RESEARCH
- A defined commensal consortium elicits CD8 T cells and anti-cancer immunity
- (2019) Takeshi Tanoue et al. NATURE
- Impact of Different Types of Diet on Gut Microbiota Profiles and Cancer Prevention and Treatment
- (2019) Rainer J. Klement et al. Medicina-Lithuania
- Commensal Microbiota Promote Lung Cancer Development via γδ T Cells
- (2019) Chengcheng Jin et al. CELL
- Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies
- (2019) Yi-Zhou Jiang et al. CANCER CELL
- Innate immunity to intracellular LPS
- (2019) Vijay A. K. Rathinam et al. NATURE IMMUNOLOGY
- Current Landscape of Immunotherapy in Breast Cancer
- (2019) Sylvia Adams et al. JAMA Oncology
- Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2
- (2019) Evan Bolyen et al. NATURE BIOTECHNOLOGY
- Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes
- (2019) Erick Riquelme et al. CELL
- Trimethylamine N-Oxide Binds and Activates PERK to Promote Metabolic Dysfunction
- (2019) Sifan Chen et al. Cell Metabolism
- Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy
- (2019) Diego Chowell et al. NATURE MEDICINE
- The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients
- (2018) Vyara Matson et al. SCIENCE
- Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2’s q2-feature-classifier plugin
- (2018) Nicholas A. Bokulich et al. Microbiome
- Fecal microbiota transplantation: Review and update
- (2018) Jiunn-Wei Wang et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential
- (2018) Adam B. Roberts et al. NATURE MEDICINE
- Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
- (2018) Peter Schmid et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
- (2017) Yupeng Wang et al. NATURE
- Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
- (2017) V. Gopalakrishnan et al. SCIENCE
- Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
- (2017) Bertrand Routy et al. SCIENCE
- Short Chain Fatty Acids in the Colon and Peripheral Tissues: A Focus on Butyrate, Colon Cancer, Obesity and Insulin Resistance
- (2017) Sean McNabney et al. Nutrients
- Uncovering the trimethylamine-producing bacteria of the human gut microbiota
- (2017) Silke Rath et al. Microbiome
- Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
- (2016) Jianjun Gao et al. CELL
- Augmentation of Immune Checkpoint Cancer Immunotherapy with IL18
- (2016) Z. Ma et al. CLINICAL CANCER RESEARCH
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease
- (2016) Tina J. Hieken et al. Scientific Reports
- Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis
- (2015) Zeneng Wang et al. CELL
- PD-L1 Expression as a Predictive Biomarker in Cancer Immunotherapy
- (2015) S. P. Patel et al. MOLECULAR CANCER THERAPEUTICS
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer
- (2015) Hossein Borghaei et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma
- (2015) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis
- (2015) A. L. Geis et al. Cancer Discovery
- ER stress-induced cell death mechanisms
- (2013) Renata Sano et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- GSVA: gene set variation analysis for microarray and RNA-Seq data
- (2013) Sonja Hänzelmann et al. BMC BIOINFORMATICS
- Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
- (2013) Robert A Koeth et al. NATURE MEDICINE
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Host-Gut Microbiota Metabolic Interactions
- (2012) J. K. Nicholson et al. SCIENCE
- The Footprints of Gut Microbial–Mammalian Co-Metabolism
- (2011) Xiaojiao Zheng et al. JOURNAL OF PROTEOME RESEARCH
- Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
- (2011) Zeneng Wang et al. NATURE
- Metagenomic biomarker discovery and explanation
- (2011) Nicola Segata et al. GENOME BIOLOGY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors
- (2009) François Ghiringhelli et al. NATURE MEDICINE
- Pyroptosis: host cell death and inflammation
- (2009) Tessa Bergsbaken et al. NATURE REVIEWS MICROBIOLOGY
- From endoplasmic-reticulum stress to the inflammatory response
- (2008) Kezhong Zhang et al. NATURE
- Hepatitis B virus and hepatocellular carcinoma
- (2004) Patrick Arbuthnot et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started