Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death

The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

(2019) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Recent insights into the structure of TFIID, its assembly, and its binding to core promoter

(2019) Avinash B Patel et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK

(2018) Francine F.S. Ke et al.   CELL

Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy

(2018) Meaghan Van Alstyne et al.   GENES & DEVELOPMENT

Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA polymerase II transcription

(2018) Farrah El-Saafin et al.   HUMAN MOLECULAR GENETICS

BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome

(2018) Gabrielle Olley et al.   NATURE GENETICS

Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities

(2018) Stephanie Grabow et al.   Cell Reports

Mcl-1 and Bcl-xL are essential for survival of the developing nervous system

(2018) Lauren C. Fogarty et al.   CELL DEATH AND DIFFERENTIATION

Structure of human TFIID and mechanism of TBP loading onto promoter DNA

(2018) Avinash B. Patel et al.   SCIENCE

Structure of promoter-bound TFIID and model of human pre-initiation complex assembly

(2016) Robert K. Louder et al.   NATURE

MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond

(2016) Jean-Christophe Marine et al.   Cold Spring Harbor Perspectives in Medicine

TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations

(2015) Jason A. O’Rawe et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes

(2015) Bo Yuan et al.   JOURNAL OF CLINICAL INVESTIGATION

An interconnected hierarchical model of cell death regulation by the BCL-2 family

(2015) Hui-Chen Chen et al.   NATURE CELL BIOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Cytoplasmic TAF2–TAF8–TAF10 complex provides evidence for nuclear holo–TFIID assembly from preformed submodules

(2015) Simon Trowitzsch et al.   Nature Communications

Accelerating Novel Candidate Gene Discovery in Neurogenetic Disorders via Whole-Exome Sequencing of Prescreened Multiplex Consanguineous Families

(2015) Anas M. Alazami et al.   Cell Reports

Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity

(2014) B Bardot et al.   ONCOGENE

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation

(2014) Daniil Alpern et al.   eLife

Core promoter factor TAF9B regulates neuronal gene expression

(2014) Francisco J Herrera et al.   eLife

Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery

(2013) M. Bezzi et al.   GENES & DEVELOPMENT

The architecture of human general transcription factor TFIID core complex

(2013) Christoph Bieniossek et al.   NATURE

The Subread aligner: fast, accurate and scalable read mapping by seed-and-vote

(2013) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Microcephaly Thin Corpus Callosum Intellectual Disability Syndrome Caused by Mutated TAF2

(2013) Shlomit Hellman-Aharony et al.   PEDIATRIC NEUROLOGY

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal

(2012) S. A. Fietz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights into the function of transcription factor TFIID from recent structural studies

(2011) Gabor Papai et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

ROAST: rotation gene set tests for complex microarray experiments

(2010) Di Wu et al.   BIOINFORMATICS

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

MDM4 (MDMX) and its Transcript Variants

(2009) F. Mancini et al.   CURRENT GENOMICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Neural Differentiation of Embryonic Stem Cells In Vitro: A Road Map to Neurogenesis in the Embryo

(2009) Elsa Abranches et al.   PLoS One

Dominant and Redundant Functions of TFIID Involved in the Regulation of Hepatic Genes

(2008) Antonis Tatarakis et al.   MOLECULAR CELL

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH