Synthetic mammalian signaling circuits for robust cell population control

Macrophages employ quorum licensing to regulate collective activation

(2020) Joseph J. Muldoon et al.   Nature Communications

Communication codes in developmental signaling pathways

(2019) Pulin Li et al.   DEVELOPMENT

CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity

(2019) Bryan D. Choi et al.   NATURE BIOTECHNOLOGY

ilastik: interactive machine learning for (bio)image analysis

(2019) Stuart Berg et al.   NATURE METHODS

Rock-paper-scissors: Engineered population dynamics increase genetic stability

(2019) Michael J. Liao et al.   SCIENCE

Design and Analysis of a Proportional-Integral-Derivative Controller with Biological Molecules

(2019) Michael Chevalier et al.   Cell Systems

Circuit Design Features of a Stable Two-Cell System

(2018) Xu Zhou et al.   CELL

Programming self-organizing multicellular structures with synthetic cell-cell signaling

(2018) Satoshi Toda et al.   SCIENCE

Bistable emergence of oscillations in growingBacillus subtilisbiofilms

(2018) Rosa Martinez-Corral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of Evolutionarily Stable Microbial Kill Switches

(2018) Finn Stirling et al.   MOLECULAR CELL

Synthetic mammalian pattern formation driven by differential diffusivity of Nodal and Lefty

(2018) Ryoji Sekine et al.   Nature Communications

Biphasic response as a mechanism against mutant takeover in tissue homeostasis circuits

(2017) Omer Karin et al.   Molecular Systems Biology

Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18

(2017) Biliang Hu et al.   Cell Reports

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

(2016) Leonardo Morsut et al.   CELL

Synchronous long-term oscillations in a synthetic gene circuit

(2016) Laurent Potvin-Trottier et al.   NATURE

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Quorum sensing signal–response systems in Gram-negative bacteria

(2016) Kai Papenfort et al.   NATURE REVIEWS MICROBIOLOGY

Synthetic Morphogenesis

(2016) Brian P. Teague et al.   Cold Spring Harbor Perspectives in Biology

Quorum Sensing Communication Modules for Microbial Consortia

(2016) Spencer R. Scott et al.   ACS Synthetic Biology

Rapid Protein Depletion in Human Cells by Auxin-Inducible Degron Tagging with Short Homology Donors

(2016) Toyoaki Natsume et al.   Cell Reports

Characterization of an Indole-3-Acetamide Hydrolase from Alcaligenes faecalis subsp. parafaecalis and Its Application in Efficient Preparation of Both Enantiomers of Chiral Building Block 2,3-Dihydro-1,4-Benzodioxin-2-Carboxylic Acid

(2016) Pradeep Mishra et al.   PLoS One

Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations

(2015) Chih-Chiang Chen et al.   CELL

BMP gradients: A paradigm for morphogen-mediated developmental patterning

(2015) E. Bier et al.   SCIENCE

Cell–Cell Communication in Yeast Using Auxin Biosynthesis and Auxin Responsive CRISPR Transcription Factors

(2015) Arjun Khakhar et al.   ACS Synthetic Biology

Paradoxical Signaling by a Secreted Molecule Leads to Homeostasis of Cell Levels

(2014) Yuval Hart et al.   CELL

Modular Extracellular Sensor Architecture for Engineering Mammalian Cell-based Devices

(2014) Nichole M. Daringer et al.   ACS Synthetic Biology

Synthetic two-way communication between mammalian cells

(2012) William Bacchus et al.   NATURE BIOTECHNOLOGY

Rapid and orthogonal logic gating with a gibberellin-induced dimerization system

(2012) Takafumi Miyamoto et al.   Nature Chemical Biology

Segregation of molecules at cell division reveals native protein localization

(2012) Dirk Landgraf et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Synthetic Signal Propagation Through Direct Cell-Cell Interaction

(2012) M. Matsuda et al.   Science Signaling

Synthetic quorum-sensing circuit to control consortial biofilm formation and dispersal in a microfluidic device

(2012) Seok Hoon Hong et al.   Nature Communications

IL-12 Release by Engineered T Cells Expressing Chimeric Antigen Receptors Can Effectively Muster an Antigen-Independent Macrophage Response on Tumor Cells That Have Shut Down Tumor Antigen Expression

(2011) M. Chmielewski et al.   CANCER RESEARCH

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

(2011) Antonio Di Stasi et al.   NEW ENGLAND JOURNAL OF MEDICINE

The main auxin biosynthesis pathway in Arabidopsis

(2011) K. Mashiguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of the Optimal Concentration of Several Selective Drugs Useful for Generating Multi-Transgenic Porcine Embryonic Fibroblasts

(2011) M Sato et al.   REPRODUCTION IN DOMESTIC ANIMALS

Engineering the ABA Plant Stress Pathway for Regulation of Induced Proximity

(2011) F.-S. Liang et al.   Science Signaling

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

The segmentation clock mechanism moves up a notch

(2010) Sarah Gibb et al.   TRENDS IN CELL BIOLOGY

Globally optimal stitching of tiled 3D microscopic image acquisitions

(2009) S. Preibisch et al.   BIOINFORMATICS

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

(2009) Kohei Nishimura et al.   NATURE METHODS

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms

(2009) A Satyanarayana et al.   ONCOGENE