Tumor-associated macrophage derived IL-6 enriches cancer stem cell population and promotes breast tumor progression via Stat-3 pathway

Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression

(2021) Ramesh Butti et al.   ONCOGENE

Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

(2020) Jesse M. Jaynes et al.   Science Translational Medicine

The p38/MKP-1 signaling axis in oral cancer: Impact of tumor-associated macrophages

(2020) Zhenning Li et al.   ORAL ONCOLOGY

Macrophage Activation Markers, CD163 and CD206, in Acute-on-Chronic Liver Failure

(2020) Marlene Christina Nielsen et al.   Cells

Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells

(2020) Karina E. Gomez et al.   CANCER RESEARCH

Epimagnolin A inhibits IL‐6 production by inhibiting p38/NF‐κB and AP‐1 signaling pathways in PMA‐stimulated THP‐1 cells

(2019) Hyun‐Woo Chun et al.   ENVIRONMENTAL TOXICOLOGY

Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling

(2019) Xiaohong Ye et al.   Nature Communications

Inhibition of M2-like macrophages by all-trans retinoic acid prevents cancer initiation and stemness in osteosarcoma cells

(2019) Xue-jing Shao et al.   ACTA PHARMACOLOGICA SINICA

Immunomodulatory Effects of Colistin on Macrophages in Rats by Activating the p38/MAPK Pathway

(2019) Jin Wang et al.   Frontiers in Pharmacology

Ontogeny of Tumor-Associated Macrophages

(2019) Marie Laviron et al.   Frontiers in Immunology

Role of the Microenvironment in Regulating Normal and Cancer Stem Cell Activity: Implications for Breast Cancer Progression and Therapy Response

(2019) Vasudeva Bhat et al.   Cancers

Cancer Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Is Dispensable for the Progression of 4T1 Murine Breast Cancer

(2019) Teizo Yoshimura et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway

(2018) Dhiraj Kumar et al.   BMC CANCER

Differential expression of IL-6/IL-6R and MAO-A regulates invasion/angiogenesis in breast cancer

(2018) Rashmi Bharti et al.   BRITISH JOURNAL OF CANCER

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Tumor-associated macrophage-derived cytokines enhance cancer stem-like characteristics through epithelial–mesenchymal transition

(2018) Yongxu Chen et al.   OncoTargets and Therapy

Systematic literature review of IL-6 as a biomarker or treatment target in patients with gastric, bile duct, pancreatic and colorectal cancer

(2018) Noomi Vainer et al.   Oncotarget

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis

(2017) Mei Zhou et al.   Nature Communications

Cancer-associated fibroblasts enhance metastatic potential of lung cancer cells through IL-6/STAT3 signaling pathway

(2017) Limin Wang et al.   Oncotarget

Notch1-MAPK Signaling Axis Regulates CD133 + Cancer Stem Cell-Mediated Melanoma Growth and Angiogenesis

(2016) Dhiraj Kumar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The p38 MAPK inhibitor SB203580 differentially modulates LPS-induced interleukin 6 expression in macrophages

(2015) Qinghai Shi et al.   Central European Journal of Immunology

The good, the bad, and the ugly of interleukin-6 signaling

(2014) J. J. Fuster et al.   EMBO JOURNAL

Semaphorin 3A upregulates FOXO 3a-dependent MelCAM expression leading to attenuation of breast tumor growth and angiogenesis

(2014) R Mishra et al.   ONCOGENE

Interleukin-6 released by colon cancer-associated fibroblasts is critical for tumour angiogenesis: anti-interleukin-6 receptor antibody suppressed angiogenesis and inhibited tumour–stroma interaction

(2013) T Nagasaki et al.   BRITISH JOURNAL OF CANCER

Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin

(2013) S Kale et al.   ONCOGENE

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL