HIF-1α stimulates the progression of oesophageal squamous cell carcinoma by activating the Wnt/β-catenin signalling pathway

Advances in Drug Resistance of Esophageal Cancer: From the Perspective of Tumor Microenvironment

(2021) Siyuan Luan et al.   Frontiers in Cell and Developmental Biology

Targeting the Wnt/β-catenin signaling pathway in cancer

(2020) Ya Zhang et al.   Journal of Hematology & Oncology

Hypoxia Dictates Metabolic Rewiring of Tumors: Implications for Chemoresistance

(2020) Dimas Carolina Belisario et al.   Cells

Hypoxia inducible factors in the tumor microenvironment as therapeutic targets of cancer stem cells

(2019) Farnaz Hajizadeh et al.   LIFE SCIENCES

Role of hypoxia in cancer therapy by regulating the tumor microenvironment

(2019) Xinming Jing et al.   Molecular Cancer

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages

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Hypoxia-induced TUFT1 promotes the growth and metastasis of hepatocellular carcinoma by activating the Ca2+/PI3K/AKT pathway

(2018) Changwei Dou et al.   ONCOGENE

The role of hypoxia-inducible factors in metabolic diseases

(2018) Frank J. Gonzalez et al.   Nature Reviews Endocrinology

EMT Transition States during Tumor Progression and Metastasis

(2018) Ievgenia Pastushenko et al.   TRENDS IN CELL BIOLOGY

Oesophageal cancer

(2017) Jesper Lagergren et al.   LANCET

Upregulation of Wnt signaling under hypoxia promotes lung cancer progression

(2017) Chun-Fu Hong et al.   ONCOLOGY REPORTS

Hypoxia-inducible factor-1α promotes cell survival during ammonia stress response in ovarian cancer stem-like cells

(2017) Shojiro Kitajima et al.   Oncotarget

Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma

(2017) Wei Xu et al.   Scientific Reports

Fra-1 Regulates the Expression of HMGA1, Which is Associated with a Poor Prognosis in Human Esophageal Squamous Cell Carcinoma

(2016) Takeshi Toyozumi et al.   ANNALS OF SURGICAL ONCOLOGY

Nuclear expression of TCF4/TCF7L2 is correlated with poor prognosis in patients with esophageal squamous cell carcinoma

(2016) Hideyuki Ishiguro et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis

(2016) Abdol-Hossein Rezaeian et al.   NATURE CELL BIOLOGY

APR-246 potently inhibits tumour growth and overcomes chemoresistance in preclinical models of oesophageal adenocarcinoma

(2015) David S H Liu et al.   GUT

Hypoxia-inducible factor-1α and Wnt/β-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells

(2015) HONG-LAN LIU et al.   Molecular Medicine Reports

Expression and Splice Variant Analysis of Human TCF4 Transcription Factor in Esophageal Cancer

(2015) Gang He et al.   Journal of Cancer

Down Regulation of Wnt Signaling Mitigates Hypoxia-Induced Chemoresistance in Human Osteosarcoma Cells

(2014) Donald J. Scholten et al.   PLoS One

Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint

(2013) Xiaoming Ju et al.   CANCER RESEARCH

Wnt/β-catenin signaling enhances hypoxia-induced epithelial–mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling

(2013) Qi Zhang et al.   CARCINOGENESIS

Oesophageal carcinoma

(2013) Arjun Pennathur et al.   LANCET

Metabolic preconditioning of mammalian cells: mimetic agents for hypoxia lack fidelity in promoting phosphorylation of pyruvate dehydrogenase

(2012) Apurva Borcar et al.   CELL AND TISSUE RESEARCH

Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression

(2012) Z.-Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opposing roles for HIF-1  and HIF-2  in the regulation of angiogenesis by mononuclear phagocytes

(2010) T. D. Eubank et al.   BLOOD

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

Melatonin modulates the expression of VEGF and HIF-1α induced by CoCl2in cultured cancer cells

(2007) Min Dai et al.   JOURNAL OF PINEAL RESEARCH