Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma

KLF4 transcriptionally activates non-canonical WNT5A to control epithelial stratification

(2016) Marie-Pier Tetreault et al.   Scientific Reports

Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis

(2015) Min-Zu Wu et al.   CANCER RESEARCH

HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine

(2015) T. Bishop et al.   CIRCULATION RESEARCH

HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells

(2015) Lihua Wu et al.   Oncotarget

HIF-1α pathway: role, regulation and intervention for cancer therapy

(2015) Georgina N. Masoud et al.   Acta Pharmaceutica Sinica B

miR-30-5p Functions as a Tumor Suppressor and Novel Therapeutic Tool by Targeting the Oncogenic Wnt/β-Catenin/BCL9 Pathway

(2014) Jian-Jun Zhao et al.   CANCER RESEARCH

WNT/β-catenin signaling and hepatocellular carcinoma

(2014) Jack R. Wands et al.   HEPATOLOGY

Hypoxia-inducible factor 1 and its role in viral carcinogenesis

(2014) Sean Cuninghame et al.   VIROLOGY

Wnt/β-catenin signaling enhances hypoxia-induced epithelial–mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling

(2013) Qi Zhang et al.   CARCINOGENESIS

Identification of a Novel Role of ZMIZ2 Protein in Regulating the Activity of the Wnt/β-Catenin Signaling Pathway

(2013) Suk Hyung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prognostic Significance of BCL9 Expression in Hepatocellular Carcinoma

(2013) Jiyeon Hyeon et al.   Korean Journal of Pathology

Links between metabolism and cancer

(2012) C. V. Dang   GENES & DEVELOPMENT

Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway

(2012) Hai-Xiang Sun et al.   HEPATOLOGY

Targeted Disruption of the BCL9/ -Catenin Complex Inhibits Oncogenic Wnt Signaling

(2012) K. Takada et al.   Science Translational Medicine

HIF-1 versus HIF-2 — Is one more important than the other?

(2012) Agnieszka Loboda et al.   VASCULAR PHARMACOLOGY

HIF-1α Confers Aggressive Malignant Traits on Human Tumor Cells Independent of Its Canonical Transcriptional Function

(2011) Young-Gun Yoo et al.   CANCER RESEARCH

MicroRNA-30c-2* Expressed in Ovarian Cancer Cells Suppresses Growth Factor-Induced Cellular Proliferation and Downregulates the Oncogene BCL9

(2011) W. Jia et al.   MOLECULAR CANCER RESEARCH

HIF-1α versus HIF-2α in endothelial cells and vascular functions: Is there a master in angiogenesis regulation?

(2010) Nicolas Skuli et al.   CELL CYCLE

Roles of hypoxia-inducible factor-1α (HIF-1α) versus HIF-2α in the survival of hepatocellular tumor spheroids

(2010) Heidi Menrad et al.   HEPATOLOGY

O2 regulates stem cells through Wnt/β-catenin signalling

(2010) Jolly Mazumdar et al.   NATURE CELL BIOLOGY

HIF-2  deletion promotes Kras-driven lung tumor development

(2010) J. Mazumdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial deletion of hypoxia-inducible factor-2  (HIF-2 ) alters vascular function and tumor angiogenesis

(2009) N. Skuli et al.   BLOOD

BCL9 Promotes Tumor Progression by Conferring Enhanced Proliferative, Metastatic, and Angiogenic Properties to Cancer Cells

(2009) M. Mani et al.   CANCER RESEARCH

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells

(2008) Marc de la Roche et al.   BMC CANCER

Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma

(2008) A Bengochea et al.   BRITISH JOURNAL OF CANCER

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION

Cell-Type-Specific Function of BCL9 Involves a Transcriptional Activation Domain That Synergizes with  -Catenin

(2008) C. Sustmann et al.   MOLECULAR AND CELLULAR BIOLOGY