Explore the variation of MMP3, JNK, p38 MAPKs, and autophagy at the early stage of osteoarthritis

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis

(2015) Hyun Hwang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis

(2015) Giuseppe Musumeci et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pinocembrin inhibits matrix metalloproteinase expression in chondrocytes

(2015) Dawei Zhang et al.   IUBMB LIFE

Activation of MAPK Is Required for ROS Generation and Exocytosis in HMC-1 Cells Induced by Trichomonas vaginalis-Derived Secretory Products

(2015) Giimaa Narantsogt et al.   KOREAN JOURNAL OF PARASITOLOGY

Activate autophagy to prevent cartilage degeneration?

(2015) Caroline Barranco   Nature Reviews Rheumatology

Carnosol Inhibits Pro-Inflammatory and Catabolic Mediators of Cartilage Breakdown in Human Osteoarthritic Chondrocytes and Mediates Cross-Talk between Subchondral Bone Osteoblasts and Chondrocytes

(2015) Christelle Sanchez et al.   PLoS One

Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis

(2015) Konstantinos C Tsolis et al.   Clinical Proteomics

Signaling Pathways in Cartilage Repair

(2014) Erminia Mariani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bornyl acetate has an anti-inflammatory effect in human chondrocytes via induction of IL-11

(2014) He Yang et al.   IUBMB LIFE

Comments on “OARSI guidelines for the non-surgical management of knee osteoarthritis”

(2014) P. du Souich   OSTEOARTHRITIS AND CARTILAGE

Expression and significance of MMP3 in synovium of knee joint at different stage in osteoarthritis patients

(2014) Jun-Jie Chen et al.   Asian Pacific Journal of Tropical Medicine

Matrix metalloproteinase protein expression profiles cannot distinguish between normal and early osteoarthritic synovial fluid

(2012) Bryan J Heard et al.   BMC MUSCULOSKELETAL DISORDERS

Gene Expression Analyses of Subchondral Bone in Early Experimental Osteoarthritis by Microarray

(2012) RongKai Zhang et al.   PLoS One

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection

(2011) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Autophagy modulates osteoarthritis-related gene expression in human chondrocytes

(2011) Hiroshi Sasaki et al.   ARTHRITIS AND RHEUMATISM

Effects of a metalloproteinase inhibitor on osteochondral angiogenesis, chondropathy and pain behavior in a rat model of osteoarthritis

(2010) P.I. Mapp et al.   OSTEOARTHRITIS AND CARTILAGE

Metalloproteinases and their inhibitors—diagnostic and therapeutic opportunities in orthopedics

(2009) Björn Pasternak et al.   Acta Orthopaedica

Regulation of autophagy in human and murine cartilage: Hypoxia-inducible factor 2 suppresses chondrocyte autophagy

(2009) Jolene Bohensky et al.   ARTHRITIS AND RHEUMATISM

The Chondroprotective Agent ITZ-1 Inhibits Interleukin-1β–Induced Matrix Metalloproteinase–13 Production and Suppresses Nitric Oxide–Induced Chondrocyte Death

(2009) Haruhide Kimura et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase

(2008) Vickram Srinivas et al.   CELLS TISSUES ORGANS

Mitogen-activated protein kinases as therapeutic targets in osteoarthritis

(2008) Richard F Loeser et al.   CURRENT OPINION IN RHEUMATOLOGY