Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy

Targeting cartilage EGFR pathway for osteoarthritis treatment

(2021) Yulong Wei et al.   Science Translational Medicine

Phospholipase A2 inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression

(2021) Yulong Wei et al.   Science Advances

Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

(2020) Jana Ghitman et al.   MATERIALS & DESIGN

Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

(2019) Shannon Brown et al.   Acta Biomaterialia

The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials

(2018) X. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Liposomes and polymersomes: a comparative review towards cell mimicking

(2018) Emeline Rideau et al.   CHEMICAL SOCIETY REVIEWS

Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage

(2018) Masato Koike et al.   PLoS One

Cartilage-penetrating nanocarriers improve delivery and efficacy of growth factor treatment of osteoarthritis

(2018) Brett C. Geiger et al.   Science Translational Medicine

Racial Variation in Total Knee Replacement in a Diverse Nationwide Clinical Trial

(2017) Lindsey A. MacFarlane et al.   JCR-JOURNAL OF CLINICAL RHEUMATOLOGY

Nanoparticle properties for delivery to cartilage: the implications of disease state, synovial fluid, and off-target uptake

(2017) Shannon Brown et al.   MOLECULAR PHARMACEUTICS

Superoxide Dismutase-Loaded Porous Polymersomes as Highly Efficient Antioxidants for Treating Neuropathic Pain

(2017) Sonia Kartha et al.   Advanced Healthcare Materials

Loading-Induced Reduction in Sclerostin as a Mechanism of Subchondral Bone Plate Sclerosis in Mouse Knee Joints During Late-Stage Osteoarthritis

(2017) Haoruo Jia et al.   Arthritis & Rheumatology

ROS/oxidative stress signaling in osteoarthritis

(2016) Panagiotis Lepetsos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future

(2016) M.A. Karsdal et al.   OSTEOARTHRITIS AND CARTILAGE

EGFR signaling is critical for maintaining the superficial layer of articular cartilage and preventing osteoarthritis initiation

(2016) Haoruo Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent Trends in Preparation of Poly(lactide-co-glycolide) Nanoparticles by Mixing Polymeric Organic Solution with Antisolvent

(2015) Edel Sah et al.   Journal of Nanomaterials

The Relationship of Autophagy Defects to Cartilage Damage During Joint Aging in a Mouse Model

(2015) Beatriz Caramés et al.   Arthritis & Rheumatology

Particle-based technologies for osteoarthritis detection and therapy

(2015) Taylor E. Kavanaugh et al.   Drug Delivery and Translational Research

Intracellular Implantation of Enzymes in Hollow Silica Nanospheres for Protein Therapy: Cascade System of Superoxide Dismutase and Catalase

(2014) Feng-Peng Chang et al.   Small

Avidin as a model for charge driven transport into cartilage and drug delivery for treating early stage post-traumatic osteoarthritis

(2013) Ambika G. Bajpayee et al.   BIOMATERIALS

Nanoparticles for Targeted Delivery of Antioxidant Enzymes to the Brain after Cerebral Ischemia and Reperfusion Injury

(2013) Xiang Yun et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The epidemiology and impact of pain in osteoarthritis

(2013) T. Neogi   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis: A disease of the joint as an organ

(2012) Richard F. Loeser et al.   ARTHRITIS AND RHEUMATISM

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Isolation and Characterization of Multipotential Mesenchymal Cells from the Mouse Synovium

(2012) Ippei Futami et al.   PLoS One

Superoxide dismutase downregulation in osteoarthritis progression and end-stage disease

(2010) J. L. Scott et al.   ANNALS OF THE RHEUMATIC DISEASES

SOD Antioxidant Nanoreactors: Influence of Block Copolymer Composition on the Nanoreactor Efficiency

(2010) Ozana Onaca et al.   MACROMOLECULAR BIOSCIENCE

The role of synovitis in osteoarthritis

(2010) Claire Y. J. Wenham et al.   Therapeutic Advances in Musculoskeletal Disease

Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

(2009) Beatrix Bartok et al.   IMMUNOLOGICAL REVIEWS

Mitochondrial Dysregulation of Osteoarthritic Human Articular Chondrocytes Analyzed by Proteomics

(2008) Cristina Ruiz-Romero et al.   MOLECULAR & CELLULAR PROTEOMICS

Joint fluid antioxidants are decreased in osteoarthritic joints compared to joints with macroscopically intact cartilage and subacute injury

(2008) E.A. Regan et al.   OSTEOARTHRITIS AND CARTILAGE