ATP-exhausted nanocomplexes for intratumoral metabolic intervention and photoimmunotherapy

The cancer metabolic reprogramming and immune response

(2021) Longzheng Xia et al.   Molecular Cancer

Immunostimulant hydrogel for the inhibition of malignant glioma relapse post-resection

(2021) Jing Zhang et al.   Nature Nanotechnology

Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

(2021) Chi Zhang et al.   Nature Communications

Self‐Mineralized Photothermal Bacteria Hybridizing with Mitochondria‐Targeted Metal–Organic Frameworks for Augmenting Photothermal Tumor Therapy

(2020) Qi‐Wen Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Engineering a Therapy‐Induced “Immunogenic Cancer Cell Death” Amplifier to Boost Systemic Tumor Elimination

(2020) Bei Li et al.   ADVANCED FUNCTIONAL MATERIALS

Metabolic Modulation of the Tumor Microenvironment Leads to Multiple Checkpoint Inhibition and Immune Cell Infiltration

(2020) David Kolb et al.   ACS Nano

Intervening Tumor Progression by Coupling Bacteria Respiration with Tumor Metabolism

(2020) Qi-Wen Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Eliciting Immunogenic Cell Death via a Unitized Nanoinducer

(2020) Zan Dai et al.   NANO LETTERS

IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

(2020) Ahmed Sadik et al.   CELL

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

(2020) Liyang Cui et al.   NATURE BIOTECHNOLOGY

GSH depletion liposome adjuvant for augmenting the photothermal immunotherapy of breast cancer

(2020) Zhanwei Zhou et al.   Science Advances

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

(2019) Michael Platten et al.   NATURE REVIEWS DRUG DISCOVERY

Dual ATP and pH responsive ZIF-90 nanosystem with favorable biocompatibility and facile post-modification improves therapeutic outcomes of triple negative breast cancer in vivo

(2019) Zhenqi Jiang et al.   BIOMATERIALS

Restraining Cancer Cells by Dual Metabolic Inhibition with a Mitochondrion-Targeted Platinum(II) Complex

(2019) Kun Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

(2019) Wei Li et al.   Nature Communications

Targeting T cell metabolism in the tumor microenvironment: an anti-cancer therapeutic strategy

(2019) Zhongping Yin et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Intra/Extracellular Lactic Acid Exhaustion for Synergistic Metabolic Therapy and Immunotherapy of Tumors

(2019) Fan Gao et al.   ADVANCED MATERIALS

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Zinc(II)-Dipicolylamine Coordination Nanotheranostics: Toward Synergistic Nanomedicine by Combined Photo/Gene Therapy

(2018) Chengchao Chu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

(2017) Yuanzeng Min et al.   Nature Nanotechnology

Surface chemistry governs cellular tropism of nanoparticles in the brain

(2017) Eric Song et al.   Nature Communications

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity

(2016) Tania Løve Aaes et al.   Cell Reports

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

The effect of hyperbranched polyglycerol coatings on drug delivery using degradable polymer nanoparticles

(2014) Yang Deng et al.   BIOMATERIALS

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

(2014) Kıvanç Birsoy et al.   NATURE