Bottom-up assembly of target-specific cytotoxic synthetic cells

Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

(2022) Oskar Staufer et al.   Nature Communications

Vesicle Induced Receptor Sequestration: Mechanisms behind Extracellular Vesicle‐Based Protein Signaling

(2022) Oskar Staufer et al.   Advanced Science

Bottom-up assembly of biomedical relevant fully synthetic extracellular vesicles

(2021) Oskar Staufer et al.   Science Advances

Bottom‐Up Assembly of Functional Intracellular Synthetic Organelles by Droplet‐Based Microfluidics

(2020) Oskar Staufer et al.   Small

Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts

(2020) Tarryn E. Miller et al.   SCIENCE

Interfacing Living and Synthetic Cells as an Emerging Frontier in Synthetic Biology

(2020) Yuval Elani   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Artificial cells drive neural differentiation

(2020) Ö. Duhan Toparlak et al.   Science Advances

Droplet-Based Cytotoxicity Assay: Implementation of Time-Efficient Screening of Antitumor Activity of Natural Killer Cells

(2020) Silvia Antona et al.   ACS Omega

Microfluidic production and characterization of biofunctionalized giant unilamellar vesicles for targeted intracellular cargo delivery

(2020) Oskar Staufer et al.   BIOMATERIALS

Synthetic cell division via membrane-transforming molecular assemblies

(2019) Simon Kretschmer et al.   BMC BIOLOGY

One-Pot Assembly of Complex Giant Unilamellar Vesicle-Based Synthetic Cells

(2019) Kerstin Göpfrich et al.   ACS Synthetic Biology

Research progress and design optimization of CAR‐T therapy for pancreatic ductal adenocarcinoma

(2019) Tianjiao Li et al.   Cancer Medicine

Mimicking Cellular Signaling Pathways within Synthetic Multicompartment Vesicles with Triggered Enzyme Activity and Induced Ion Channel Recruitment

(2019) Sagana Thamboo et al.   ADVANCED FUNCTIONAL MATERIALS

Engineered T Cell Therapy for Cancer in the Clinic

(2019) Lijun Zhao et al.   Frontiers in Immunology

Bottom-up synthetic biology: reconstitution in space and time

(2019) Haiyang Jia et al.   CURRENT OPINION IN BIOTECHNOLOGY

Engineering strategies to overcome the current roadblocks in CAR T cell therapy

(2019) Sarwish Rafiq et al.   Nature Reviews Clinical Oncology

Mastering Complexity: Towards Bottom-up Construction of Multifunctional Eukaryotic Synthetic Cells

(2018) Kerstin Göpfrich et al.   TRENDS IN BIOTECHNOLOGY

Charge-controlled microfluidic formation of lipid-based single- and multicompartment systems

(2018) Barbara Haller et al.   LAB ON A CHIP

TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation

(2018) Laura Faletti et al.   Cell Death & Disease

Light-Guided Motility of a Minimal Synthetic Cell

(2018) Solveig M. Bartelt et al.   NANO LETTERS

Synthetic beta cells for fusion-mediated dynamic insulin secretion

(2017) Zhaowei Chen et al.   Nature Chemical Biology

Anti-Fas Antibody Conjugated Nanoparticles Enhancing the Antitumor Effect of Camptothecin by Activating the Fas–FasL Apoptotic Pathway

(2016) Hongliang Yu et al.   ACS Applied Materials & Interfaces

Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8

(2016) Christina Helmke et al.   CELL RESEARCH

CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts

(2016) Laetitia Saint-Paul et al.   Oncotarget

Enhancing the antitumor efficacy of a cell-surface death ligand by covalent membrane display

(2015) Pradeep M. Nair et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network representations of immune system complexity

(2015) Naeha Subramanian et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

NK cell-mediated antibody-dependent cellular cytotoxicity in cancer immunotherapy

(2015) Wei Wang   Frontiers in Immunology

Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells

(2015) Baolin Zhang et al.   Oncotarget

Principles and mechanisms of CD95 activation

(2014) Harald Wajant   BIOLOGICAL CHEMISTRY

Polarized release of T-cell-receptor-enriched microvesicles at the immunological synapse

(2014) Kaushik Choudhuri et al.   NATURE

Synthesis of Nanostructured and Biofunctionalized Water-in-Oil Droplets as Tools for Homing T Cells

(2013) Ilia Platzman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Liposomes Decorated with Apo2L/TRAIL Overcome Chemoresistance of Human Hematologic Tumor Cells

(2013) Diego De Miguel et al.   MOLECULAR PHARMACEUTICS

Comparative studies of polyethylene glycol-modified liposomes prepared using different PEG-modification methods

(2012) Koji Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Synthesizing artificial cells from giant unilamellar vesicles: State-of-the art in the development of microfluidic technology

(2012) Sandro Matosevic   BIOESSAYS

Overview of the immune response

(2010) David D. Chaplin   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lipid map of the mammalian cell

(2010) G. van Meer et al.   JOURNAL OF CELL SCIENCE