Ligand stimulation of CD95 induces activation of Plk3 followed by phosphorylation of caspase-8

Tumor-infiltrating CD8+T lymphocytes associated with clinical outcome in anal squamous cell carcinoma

(2015) Wan-Hsiang Hu et al.   JOURNAL OF SURGICAL ONCOLOGY

The role of Plk3 in oncogenesis

(2015) C Helmke et al.   ONCOGENE

Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer Treatment

(2015) Xiaoqi Liu   Translational Oncology

Getting TRAIL back on track for cancer therapy

(2014) J Lemke et al.   CELL DEATH AND DIFFERENTIATION

Quantitative chemical proteomics reveals a Plk1 inhibitor-compromised cell death pathway in human cells

(2014) Monika Raab et al.   CELL RESEARCH

Human papillomavirus DNA load and p16INK4aexpression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy

(2014) Franz Rödel et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis

(2014) Christoph Reissfelder et al.   JOURNAL OF CLINICAL INVESTIGATION

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

(2014) Pratyusha Mandal et al.   MOLECULAR CELL

Polo-like kinases: structural variations lead to multiple functions

(2014) Sihem Zitouni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PADI4 acts as a coactivator of Tal1 by counteracting repressive histone arginine methylation

(2014) Stephan Kolodziej et al.   Nature Communications

Plk1: unexpected roles in DNA replication

(2013) Ranadip Mandal et al.   CELL RESEARCH

pERK 1/2 inhibit Caspase-8 induced apoptosis in cancer cells by phosphorylating it in a cell cycle specific manner

(2013) Ranadip Mandal et al.   Molecular Oncology

Structural basis for the inhibition of Polo-like kinase 1

(2013) Jun Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CD95 in cancer: tool or target?

(2013) Ana Martin-Villalba et al.   TRENDS IN MOLECULAR MEDICINE

Investigation on PLK2 and PLK3 substrate recognition

(2012) M. Salvi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mitochondria: master regulators of danger signalling

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival

(2011) Andrew Oberst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells

(2011) Monika Raab et al.   Nature Communications

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

RNAi screening of the kinome identifies modulators of cisplatin response in ovarian cancer cells

(2010) Shilpi Arora et al.   GYNECOLOGIC ONCOLOGY

Dbf4 Regulates the Cdc5 Polo-like Kinase through a Distinct Non-canonical Binding Interaction

(2010) Ying-Chou Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk1/Cyclin B1 Controls Fas-Mediated Apoptosis by Regulating Caspase-8 Activity

(2010) Y. Matthess et al.   MOLECULAR AND CELLULAR BIOLOGY

mRNA turnover rate limits siRNA and microRNA efficacy

(2010) Erik Larsson et al.   Molecular Systems Biology

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

PHOSIDA 2011: the posttranslational modification database

(2010) F. Gnad et al.   NUCLEIC ACIDS RESEARCH

SLP-65 Phosphorylation Dynamics Reveals a Functional Basis for Signal Integration by Receptor-proximal Adaptor Proteins

(2009) Thomas Oellerich et al.   MOLECULAR & CELLULAR PROTEOMICS

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

(2008) Susanne Kleber et al.   CANCER CELL

Sequestration of Polo kinase to microtubules by phosphopriming-independent binding to Map205 is relieved by phosphorylation at a CDK site in mitosis

(2008) V. Archambault et al.   GENES & DEVELOPMENT