Acute Kynurenine Exposure of Rat Thoracic Aorta Induces Vascular Dysfunction <i>via</i> Superoxide Anion Production

Correlation of Indoleamine-2,3-Dioxygenase and Chronic Kidney Disease: A Pilot Study

(2021) Binbin Pan et al.   Journal of Immunology Research

Uremic Toxins in the Progression of Chronic Kidney Disease and Cardiovascular Disease: Mechanisms and Therapeutic Targets

(2021) Yong Jin Lim et al.   Toxins

RAS inhibition modulates kynurenine levels in a CKD population with and without type 2 diabetes mellitus

(2020) Valeria Cernaro et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Kynurenine produced by indoleamine 2,3-dioxygenase 2 exacerbates acute liver injury by carbon tetrachloride in mice

(2020) Masato Hoshi et al.   TOXICOLOGY

Reactive Oxygen Species and Redox Signaling in Chronic Kidney Disease

(2020) Maria V. Irazabal et al.   Cells

The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis

(2020) Yurong Cheng et al.   Scientific Reports

Endothelial Dysfunction in Chronic Kidney Disease, from Biology to Clinical Outcomes: A 2020 Update

(2020) Stefanos Roumeliotis et al.   Journal of Clinical Medicine

Molecular Mechanisms Underlying the Cardiovascular Toxicity of Specific Uremic Solutes

(2020) Jonathan D. Ravid et al.   Cells

Indoxyl sulfate induces ROS production via the aryl hydrocarbon receptor-NADPH oxidase pathway and inactivates NO in vascular tissues

(2020) Keisuke Nakagawa et al.   LIFE SCIENCES

Tryptophan Metabolism as a Pharmacological Target

(2020) Morgane Modoux et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cyclic nucleotide phosphodiesterases (PDEs) and endothelial function in ischaemic stroke. A review

(2019) Saiqa Yasmeen et al.   CELLULAR SIGNALLING

Circulating active von Willebrand factor levels are increased in chronic kidney disease and end-stage renal disease

(2019) Lisa N van der Vorm et al.   Clinical Kidney Journal

Kynurenine, a Tryptophan Metabolite That Increases with Age, Induces Muscle Atrophy and Lipid Peroxidation

(2019) Helen Kaiser et al.   Oxidative Medicine and Cellular Longevity

Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans

(2018) Vijaya B. Kolachalama et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Redox regulation of soluble guanylyl cyclase

(2018) Rohan C. Shah et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

(2018) Rafael Radi   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human AHR functions in vascular tissue: Pro- and anti-inflammatory responses of AHR agonists in atherosclerosis

(2018) Karl Walter Bock   BIOCHEMICAL PHARMACOLOGY

Tryptophan-Derived Uremic Toxins and Thrombosis in Chronic Kidney Disease

(2018) Tawfik Addi et al.   Toxins

Cardiovascular events and death in Japanese patients with chronic kidney disease

(2017) Kenichi Tanaka et al.   KIDNEY INTERNATIONAL

Peripheral kynurenine/tryptophan ratio is not a reliable marker of systemic indoleamine 2,3-dioxygenase: A lesson drawn from patients on hemodialysis

(2017) Yuanhan Chen et al.   Oncotarget

Thirty Years of Saying NO

(2016) Paul M. Vanhoutte et al.   CIRCULATION RESEARCH

Kynurenine, by activating aryl hydrocarbon receptor, decreases erythropoietin and increases hepcidin production in HepG2 cells: A new mechanism for anemia of inflammation

(2016) Theodoros Eleftheriadis et al.   EXPERIMENTAL HEMATOLOGY

Indoleamine 2,3-Dioxygenase Is Involved in the Inflammation Response of Corneal Epithelial Cells to Aspergillus fumigatus Infections

(2015) Nan Jiang et al.   PLoS One

Chronic Renal Disease and Risk of Cardiovascular Morbidity-Mortality

(2014) Antonio Santoro et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Aryl Hydrocarbon Receptor and Kynurenine: Recent Advances in Autoimmune Disease Research

(2014) Nam Trung Nguyen et al.   Frontiers in Immunology

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

(2013) Ron T Gansevoort et al.   LANCET

l-Kynurenine-induced apoptosis in human NK cells is mediated by reactive oxygen species

(2011) Hyunkeun Song et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ascorbic acid or l-arginine improves cutaneous microvascular function in chronic kidney disease

(2011) Jennifer J. DuPont et al.   JOURNAL OF APPLIED PHYSIOLOGY

Chronic Kidney Disease, Dyslipidemia, and Atherosclerosis

(2011) Tetsuo Shoji et al.   Journal of Atherosclerosis and Thrombosis

Kynurenine pathway – a new link between endothelial dysfunction and carotid atherosclerosis in chronic kidney disease patients

(2010) K Pawlak et al.   Advances in Medical Sciences

Indoxyl Sulfate-Induced Endothelial Dysfunction in Patients with Chronic Kidney Disease via an Induction of Oxidative Stress

(2010) M. Yu et al.   Clinical Journal of the American Society of Nephrology

Oxidative Stress and Endothelial Dysfunction in Aortas of Aged Spontaneously Hypertensive Rats by NOX1/2 Is Reversed by NADPH Oxidase Inhibition

(2010) Sven Wind et al.   HYPERTENSION

Aryl hydrocarbon receptor-dependent induction of the NADPH oxidase subunit NCF1/p47phox expression leading to priming of human macrophage oxidative burst

(2009) Marie-Laure Pinel-Marie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms

(2009) J. C. Schefold et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Nitric Oxide, Tetrahydrobiopterin, Oxidative Stress, and Endothelial Dysfunction in Hypertension

(2008) Eberhard Schulz et al.   ANTIOXIDANTS & REDOX SIGNALING

The kynurenines are associated with oxidative stress, inflammation and the prevalence of cardiovascular disease in patients with end-stage renal disease

(2008) Krystyna Pawlak et al.   ATHEROSCLEROSIS

Aryl Hydrocarbon Receptor Is Activated by Glucose and Regulates the Thrombospondin-1 Gene Promoter in Endothelial Cells

(2008) Pankaj Dabir et al.   CIRCULATION RESEARCH