Myoglobin: From physiological roles to potential implications in cancer

Expression of Myoglobin in Normal and Cancer Brain Tissues: Correlation With Hypoxia Markers

(2021) Marwa E. Elsherbiny et al.   Frontiers in Oncology

The peroxidatic activities of Myoglobin and Hemoglobin, their pathological consequences and possible medical interventions

(2021) Michael T. Wilson et al.   MOLECULAR ASPECTS OF MEDICINE

Myoglobin induces mitochondrial fusion thereby inhibiting breast cancer cell proliferation

(2019) Andrea Braganza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms

(2019) Halil Bagci et al.   NATURE CELL BIOLOGY

Structure and function of heme proteins regulated by diverse post-translational modifications

(2018) Ying-Wu Lin   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ectopic Myoglobin Expression Is Associated with a Favourable Outcome in Head and Neck Squamous Cell Carcinoma Patients

(2016) SEBASTIAN MELLER et al.   ANTICANCER RESEARCH

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Early dissemination seeds metastasis in breast cancer

(2016) Hedayatollah Hosseini et al.   NATURE

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

Reactive Oxygen Species in Cancer: A Dance with the Devil

(2015) Paul T. Schumacker   CANCER CELL

The Distinct Gene Regulatory Network of Myoglobin in Prostate and Breast Cancer

(2015) Anne Bicker et al.   PLoS One

Myoglobin functions in the heart

(2014) Ulrike B. Hendgen-Cotta et al.   FREE RADICAL BIOLOGY AND MEDICINE

Effect of hypoxia on angiogenesis related factors in glioblastoma cells

(2014) MARWAN EMARA et al.   ONCOLOGY REPORTS

Antioxidants Accelerate Lung Cancer Progression in Mice

(2014) V. I. Sayin et al.   Science Translational Medicine

Myoglobin expression in prostate cancer is correlated to androgen receptor expression and markers of tumor hypoxia

(2014) Sebastian Meller et al.   VIRCHOWS ARCHIV

Myoglobin expression in renal cell carcinoma is regulated by hypoxia

(2013) C.L. Behnes et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Extensive transcriptional complexity during hypoxia-regulated expression of the myoglobin gene in cancer

(2013) Anne Bicker et al.   HUMAN MOLECULAR GENETICS

Redox Reactions of Myoglobin

(2012) Mark P. Richards   ANTIOXIDANTS & REDOX SIGNALING

Myoglobin and mitochondria: A relationship bound by oxygen and nitric oxide

(2012) Christelle Kamga et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Assessment of the functional diversity of human myoglobin

(2012) Matthias Totzeck et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Endogenous Myoglobin in Breast Cancer Is Hypoxia-inducible by Alternative Transcription and Functions to Impair Mitochondrial Activity

(2011) Glen Kristiansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroglobin and myoglobin in non-small cell lung cancer: Expression, regulation and prognosis

(2011) Urszula Oleksiewicz et al.   LUNG CANCER

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells

(2010) T. A. Gorr et al.   Acta Physiologica

The Redox Activity of Hemoglobins: From Physiologic Functions to Pathologic Mechanisms

(2010) Brandon J. Reeder   ANTIOXIDANTS & REDOX SIGNALING

Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype

(2010) G Kristiansen et al.   BRITISH JOURNAL OF CANCER

Fatty acid synthase as a potential therapeutic target in cancer

(2010) Richard Flavin et al.   Future Oncology

Unmasking the Janus face of myoglobin in health and disease

(2010) U. B. Hendgen-Cotta et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Regulation of myoglobin expression

(2010) S. B. Kanatous et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Expression and Functional Regulation of Myoglobin in Epithelial Cancers

(2009) Simona Emilia Flonta et al.   AMERICAN JOURNAL OF PATHOLOGY

Both hypoxia and work are required to enhance expression of myoglobin in skeletal muscle. Focus on “Hypoxia reprograms calcium signaling and regulates myoglobin expression”

(2009) Beatrice A. Wittenberg   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nitric oxide stimulates myoglobin gene and protein expression in vascular smooth muscle

(2009) Benjamin S. Rayner et al.   BIOCHEMICAL JOURNAL

Myoglobin tames tumor growth and spread

(2009) Ulrich Flögel et al.   JOURNAL OF CLINICAL INVESTIGATION

Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis

(2009) Maria Galluzzo et al.   JOURNAL OF CLINICAL INVESTIGATION

Diverse cell-specific expression of myoglobin isoforms in brain, kidney, gill and liver of the hypoxia-tolerant carp and zebrafish

(2009) A. R. Cossins et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Non-enzymatic glycation induces structural modifications of myoglobin

(2009) Anjana Roy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hypoxia reprograms calcium signaling and regulates myoglobin expression

(2008) Shane B. Kanatous et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Systemic Spread Is an Early Step in Breast Cancer

(2008) Yves Hüsemann et al.   CANCER CELL

Cancer Cell Metabolism: Warburg and Beyond

(2008) Peggy P. Hsu et al.   CELL

Interaction of fatty acid with myoglobin

(2008) Renuka Sriram et al.   FEBS LETTERS