The peroxidatic activities of Myoglobin and Hemoglobin, their pathological consequences and possible medical interventions

βCysteine 93 in human hemoglobin: a gateway to oxidative stability in health and disease

(2020) Abdu I. Alayash   LABORATORY INVESTIGATION

Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers

(2018) Michelle Simons et al.   BIOSCIENCE REPORTS

Engineering tyrosine residues into hemoglobin enhances heme reduction, decreases oxidative stress and increases vascular retention of a hemoglobin based blood substitute

(2018) Chris E. Cooper et al.   FREE RADICAL BIOLOGY AND MEDICINE

2017 Military Supplement

(2017) Andres S. Benitez Cardenas et al.   SHOCK

Mechanisms of Toxicity and Modulation of Hemoglobin-Based Oxygen Carriers (HBOCs)

(2017) Abdu I. Alayash   SHOCK

Fetal hemoglobin is much less prone to DNA cleavage compared to the adult protein

(2017) Sandeep Chakane et al.   Redox Biology

Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design

(2016) G. G. A. Silkstone et al.   BIOCHEMICAL JOURNAL

Allopurinol attenuates rhabdomyolysis-associated acute kidney injury: Renal and muscular protection

(2016) Pedro H.F. Gois et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multicenter, Randomized, Placebo-Controlled Phase III Study of Pyridoxalated Hemoglobin Polyoxyethylene in Distributive Shock (PHOENIX)*

(2015) Jean-Louis Vincent et al.   CRITICAL CARE MEDICINE

Blood substitutes: why haven’t we been more successful?

(2014) Abdu I. Alayash   TRENDS IN BIOTECHNOLOGY

Selenium Inhibits Renal Oxidation and Inflammation But Not Acute Kidney Injury in an Animal Model of Rhabdomyolysis

(2012) Anu Shanu et al.   ANTIOXIDANTS & REDOX SIGNALING

Development of Recombinant Hemoglobin-Based Oxygen Carriers

(2012) Cornelius L. Varnado et al.   ANTIOXIDANTS & REDOX SIGNALING

Engineering Tyrosine-Based Electron Flow Pathways in Proteins: The Case of Aplysia Myoglobin

(2012) Brandon J. Reeder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Are Isofurans and Neuroprostanes Increased After Subarachnoid Hemorrhage and Traumatic Brain Injury?

(2011) Tomas B. Corcoran et al.   ANTIOXIDANTS & REDOX SIGNALING

The Redox Activity of Hemoglobins: From Physiologic Functions to Pathologic Mechanisms

(2010) Brandon J. Reeder   ANTIOXIDANTS & REDOX SIGNALING

Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure

(2010) O. Boutaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hemospan: Design Principles for a New Class of Oxygen Therapeutic

(2009) Kim D. Vandegriff et al.   ARTIFICIAL ORGANS

Correlation of F4-neuroprostanes levels in cerebrospinal fluid with outcome of aneurysmal subarachnoid hemorrhage in humans

(2009) Yu-Ping Hsieh et al.   FREE RADICAL BIOLOGY AND MEDICINE

All hemoglobin-based oxygen carriers are not created equally

(2008) Paul W. Buehler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Tyrosine Residues as Redox Cofactors in Human Hemoglobin

(2008) Brandon J. Reeder et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paracetamol (Acetaminophen): mechanisms of action

(2008) BRIAN J. ANDERSON   PEDIATRIC ANESTHESIA

Iron chelators can protect against oxidative stress through ferryl heme reduction

(2007) Brandon J. Reeder et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tyrosine as a redox-active center in electron transfer to ferryl heme in globins

(2007) Brandon J. Reeder et al.   FREE RADICAL BIOLOGY AND MEDICINE