Suppression of RNF213, a susceptibility gene for moyamoya disease, inhibits endoplasmic reticulum stress through SEL1L upregulation

Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection

(2021) Elsje G. Otten et al.   NATURE

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity

(2021) Fabien Thery et al.   Nature Communications

Mechanisms, regulation and functions of the unfolded protein response

(2020) Claudio Hetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism

(2020) Juraj Ahel et al.   eLife

Thapsigargin—From Traditional Medicine to Anticancer Drug

(2020) Agata Jaskulska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Moyamoya Disease Susceptibility Variant RNF213 p.R4810K Increases the Risk of Ischemic Stroke Attributable to Large-Artery Atherosclerosis

(2019) Shuhei Okazaki et al.   CIRCULATION

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids

(2019) Manuele Piccolis et al.   MOLECULAR CELL

Quality Control in the Endoplasmic Reticulum: Crosstalk between ERAD and UPR pathways

(2018) Jiwon Hwang et al.   TRENDS IN BIOCHEMICAL SCIENCES

Dysregulation of RNF213 promotes cerebral hypoperfusion

(2018) Takaaki Morimoto et al.   Scientific Reports

Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes

(2018) Beibei Xu et al.   Cell Reports

New Insights into the Physiological Role of Endoplasmic Reticulum-Associated Degradation

(2017) Ling Qi et al.   TRENDS IN CELL BIOLOGY

Rare variants of RNF213 and moyamoya/non-moyamoya intracranial artery stenosis/occlusion disease risk: a meta-analysis and systematic review

(2017) Xin Liao et al.   Environmental Health and Preventive Medicine

Significant association of RNF213 p.R4810K, a moyamoya susceptibility variant, with coronary artery disease

(2017) Takaaki Morimoto et al.   PLoS One

Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e

(2016) Masatoshi Hagiwara et al.   MOLECULAR CELL

A new horizon of moyamoya disease and associated health risks explored through RNF213

(2015) Akio Koizumi et al.   Environmental Health and Preventive Medicine

Effects of Oxidative Stress on the Solubility of HRD1, a Ubiquitin Ligase Implicated in Alzheimer’s Disease

(2014) Ryo Saito et al.   PLoS One

Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival

(2014) Shengyi Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ablation of Rnf213 retards progression of diabetes in the Akita mouse

(2013) Hatasu Kobayashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SEL1L Protein Critically Determines the Stability of the HRD1-SEL1L Endoplasmic Reticulum-associated Degradation (ERAD) Complex to Optimize the Degradation Kinetics of ERAD Substrates

(2011) Yasutaka Iida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knocking out the door to tunicamycin entry

(2011) M. C. Bassik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A genome-wide association study identifies RNF213 as the first Moyamoya disease gene

(2010) Fumiaki Kamada et al.   JOURNAL OF HUMAN GENETICS

GLP-1 receptor agonist attenuates endoplasmic reticulum stress-mediated β-cell damage in Akita mice

(2010) Shunsuke Yamane et al.   Journal of Diabetes Investigation

Moyamoya Disease and Moyamoya Syndrome

(2009) R. Michael Scott et al.   NEW ENGLAND JOURNAL OF MEDICINE